Orthomyxoviruses/ Influenza

Question 1

Influenzaviruses have segmented genome

Answer 1

T

Question 2

HPAI and LPAI strains differ in the number of basal amino acids in the HA protein

Answer 2

T

Question 3

HA protein of influenza viruses is responsible for the attachment to the cell

Answer 3

T

Question 4

The M2 protein of influenza viruses serves as an ion channel important in the decapsidation

Answer 4

T

Question 5

Antigenic drift means serials of point mutations in the HA and NA genes

Answer 5

T

Question 6

The NA protein in the influenza virus is responsible for the release from the infected cells

Answer 6

T

Question 7

Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the
cell

Answer 7

T

Question 8

Genetic reassortment of human and animal influenza viruses result in the occurrence of new
human influenza strains

Answer 8

T

Question 9

Bats have an important role in the epidemiology of influenza

Answer 9

F

Question 10

Antigenic shift is behind the influenza pandemics

Answer 10

T

Question 11

Influenza viruses are classified into genera by their HA and NA proteins

Answer 11

F

Question 12

Influenza causes persistent infection in donkey

Answer 12

F

Question 13

The serotype of influenza viruses is determined by their HA and NA proteins

Answer 13

T

Question 14

The influenza viruses cause respiratory signs in sea mammals

Answer 14

T

Question 15

The host range of influenza virus is determined by the NA protein

Answer 15

F

Question 16

The bird to human host switch of influenza virus is mediated by swine

Answer 16

T
But rare

Question 17

The main host of influenza is the swine

Answer 17

F

Question 18

In humans inactivated vaccines are used for the immunisation against influenza

Answer 18

T

Question 19

Antigenic drift is behind the seasonal influenza epidemics

Answer 19

T

Question 20

Antigenic shift means the reassortment of the influenzavirus genome segments

Answer 20

T

Question 21

Influenzaviruses are sensitive to drying out

Answer 21

T

Question 22

For the in vitro propagation of influenza viruses embryonated eggs is used

Answer 22

F

IN VIVO

Question 23

The high virulence of some influenza A viruses is the result of mutations in the HA gene

Answer 23

T

Question 24

Influenza viruses are classified into genera by their HA and NA proteins

Answer 24

F

Question 25

Dogs are susceptible to horse origin influenza strains

Answer 25

T

Question 26

The HPAI strains can cause CNS Signs

Answer 26

T

Question 27

HPAI causes blood vessel damages and generalised infections

Answer 27

T

Question 28

The HPAI strains are usually developed from the H5 and H7 influenza viruses

Answer 28

T

Question 29

The LPAI causes immunosuppression

Answer 29

T

Question 30

Cat is susceptible to human seasonal influenza

Answer 30

F

Question 31

HPAI strains are mutations of LPAI strains

Answer 31

T

Question 32

HPAI strains belong into a certain haemagglutinin types

Answer 32

F

Question 33

Influenzas Causes enteric symptoms in human.

Answer 33

T

Question 34

Anti-neuraminidase drugs inhibit the decapsidation of influenza viruses

Answer 34

F