Orthomyxoviruses/ Influenza Flashcards
Influenzaviruses have segmented genome
T
HPAI and LPAI strains differ in the number of basal amino acids in the HA protein
T
HA protein of influenza viruses is responsible for the attachment to the cell
T
The M2 protein of influenza viruses serves as an ion channel important in the decapsidation
T
Antigenic drift means serials of point mutations in the HA and NA genes
T
The NA protein in the influenza virus is responsible for the release from the infected cells
T
Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the
cell
T
Genetic reassortment of human and animal influenza viruses result in the occurrence of new
human influenza strains
T
Bats have an important role in the epidemiology of influenza
F
Antigenic shift is behind the influenza pandemics
T
Influenza viruses are classified into genera by their HA and NA proteins
F
Influenza causes persistent infection in donkey
F
The serotype of influenza viruses is determined by their HA and NA proteins
T
The influenza viruses cause respiratory signs in sea mammals
T
The host range of influenza virus is determined by the NA protein
F
The bird to human host switch of influenza virus is mediated by swine
T
But rare
The main host of influenza is the swine
F
In humans inactivated vaccines are used for the immunisation against influenza
T
Antigenic drift is behind the seasonal influenza epidemics
T
Antigenic shift means the reassortment of the influenzavirus genome segments
T
Influenzaviruses are sensitive to drying out
T
For the in vitro propagation of influenza viruses embryonated eggs is used
F
IN VIVO
The high virulence of some influenza A viruses is the result of mutations in the HA gene
T
Influenza viruses are classified into genera by their HA and NA proteins
F
Dogs are susceptible to horse origin influenza strains
T
The HPAI strains can cause CNS Signs
T
HPAI causes blood vessel damages and generalised infections
T
The HPAI strains are usually developed from the H5 and H7 influenza viruses
T
The LPAI causes immunosuppression
T
Cat is susceptible to human seasonal influenza
F
HPAI strains are mutations of LPAI strains
T
HPAI strains belong into a certain haemagglutinin types
F
Influenzas Causes enteric symptoms in human.
T
Anti-neuraminidase drugs inhibit the decapsidation of influenza viruses
F
