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micro 450 viruses > Orthomyxovirus > Flashcards

Orthomyxovirus Flashcards

1
Q

What factors are used to name viruses?

A
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2
Q

What is the genome structure and organization of influenza

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3
Q

How many segments does the flu have? WHat do they encode for?

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4
Q

How do avian influenza and human influenza binding differ?

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5
Q

WHat is the influenza receptor?

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6
Q

How does orthomyxovirus uncoating occur? What protein forms the channel?
What about orthomyxovirus nuclear import is unique?

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7
Q

What mechanism does orthomyxovirus perform to initiate mRNA synthesis?

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8
Q

What proteins are associated with mRNA synthesis? How is it synthesized?

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9
Q

What dictates which RNA type is made?

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10
Q

How is cRNA initiated?

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11
Q

Where are HA and NA translated?

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12
Q

What is an essential component of egress?
How has HA matured to a fusogenic state?

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13
Q

What are the main types of transmission for this virus?

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14
Q

What causes flu seasonality?

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15
Q

What are the flu vaccine types? How are they made?

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16
Q

What is the orthomyxovirus reservoir?

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17
Q

Why are pigs so crucial in transmission?

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18
Q

What occurs during binding during human to human transmission?

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19
Q

Why are people worried about H5N1?

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20
Q

WHat is antigenic drift?

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21
Q

What is shift?

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22
Q

What is reassortment?

A
23
Q

Why was the 2009 swine flu unusual? What caused this?

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24
Q

What happened with the flu of 1918?

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micro 450 viruses (4 decks)

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