Ortho Flashcards
osteoporosis is caused by these 3 things:
age-related (elderly)
post-menopausal
hypothyroidism
increased risk of fractures in elderly is due to these hormonal changes:
increased PTH & cortisol
decreased vit D3, growth hormone, & insulin-like growth factors
______ compression fractures are most common with falls in the elderly
LUMBAR
Pts on fosamax, actonel, boniva, or reclast should hint to what pathophysiology?
osteoporosis
Arthritic disorder that is associated with inflammation, pain in weight bearing joints, and sx that worsen throughout the day (evening stiffness):
OA - osteoarthritis
swelling/spurring of DISTAL interphalangeal joints
Heberden’s nodes
swelling/spurring of PROXIMAL interphalangeal joints
Bouchard’s nodes
When should OA pts stop taking glucosamine prior to surgery?
2 wks – inhibits plt aggregation/risk bleeding
Arthritic disorder associated with morning stiffness that improves with activity:
RA - rheumatoid arthritis
What lab values are elevated in the RA pt?
rheumatoid factor
anti-immunoglobulin antibody
C-reactive protein (CRP)
erythrocyte sedimentation rate (ESR)
When reviewing home medications, you notice your elderly patient is taking methotrexate (MTX), what should you start thinking?
RED FLAG –> elderly + MTX = think RA, positioning & airway issues
What medications should the RA patient receive preop?
pain –> NSAIDs, opioids
Stress dose 100mg hydrocortisone IV
Airway considerations for RA pts:
limited TMJ movement, narrowed glottic opening, & cricoarytenoid arthritis = awake fiberoptic intubation &/or regional anes
What are some preop Qs to ask your RA pt to assess possible difficult airway (prior to the physical exam)?
hoarseness in voice, dysphagia, stridor, neck tenderness
Atlantoaxial instability in RA involves what 2 vertebrae?
C1 - atlas
C2 - axis
** displaces odontoid process (dens)
atlantoaxial instability in RA pts can result in impingement/compression of the:
C-spine, medulla, & vertebral arteries
Symptoms of atlantoaxial subluxation:
HA
neck pain
Upper & lower extremity paresthesia with movement
bladder/bowel dysfunction
vertebral artery occlusion/compression symptoms:
N/V
dysphagia
blurred vision
transient loss of consciousness
Sjogren’s syndrome is associated with RA and results in:
dry eyes & mouth
An RA patient has what type of ventilation issues? (obstructive or restrictive)
RESTRICTIVE – d/t diffuse interstitial fibrosis
What is a safe vent setting for the RA patient per Dr. Castillo?
PC-Volume guarantee
Vt = 5ml/kg IBW
RA + elderly + NSAID use can result in:
gastric ulcers & renal insufficiency
What does MILS/MILI stand for?
manual in-line stabilization/immboilization
If pt is confused or uncooperative, then this type of anes is not appropriate:
neuraxial or regional
Stabilization of head, neck, & torso in neutral position for pts who have not been cleared by x-ray is referred to as:
MILS/MILI
What airway maneuver is acceptable in trauma/c-spine pts?
chin lift – results in slight c-spine movement, but is allowed to open up airway
How does aging affect FEV1?
FEV1 decreases 10% for each decade
What is the target HR for elderly?
< 80 bpm
Which NMB reversal agent is safest for elderly?
sugammadex – avoids the HR changes seen with neostigmine & glyco)
When do symptoms of FES start to present?
12-72 hrs after trauma or surgery
FES symptoms triad:
dyspnea + confusion + petechiae 12-72 hrs after trauma or surgery
Which triad symptoms is the most definitive finding of FES?
PETECHIAE - conjunctiva, oral mucosa, skin folds of chest, neck, & axilla
Normal SED rate male:
0-22 mm/hr
Normal SED rate female:
0-29 mm/hr
long bone trauma (femur) and pelvic fractures can commonly cause:
FES - fat embolism syndrome
best preventative management of FES:
early recognition
fracture stabilization/immobilization ASAP
FES symptoms can resolve in _____ if managed appropriately.
3-7 days
When can you perform neuraxial anes after a patient has received LMWH (once daily dosing)?
10-12 hrs after previous LMWH dose (if there is no indwelling catheter)
if LMWH is given twice daily dosing, what should you consider with neuraxial anes?
NO indwelling catheter — must remove 2+ hrs before next LMWH dose
How soon after a neuraxial block can a patient resume LMWH dose?
4 hrs
without prophylaxis, risk of thrombosis is ____%
40-80%
Neuraxial anesthesia is ok if a patient is on warfarin as long as the INR is:
1.5 or less
What are the 3 advantages of neuraxial anesthetics in preventing VTE formation?
increased lower extremity venous blood flow (d/t sympathectomy)
LA = systemic anti-inflammatory properties
decreased platelet reactivity
When can neuraxial block be performed after aspirin & NSAIDs are stopped?
no additional precautions with these 2 medications
When can neuraxial block be performed after CLOPIDOGREL (PLAVIX) is stopped?
5-7 days
When can neuraxial block be performed after PRASUGREL (EFFIENT) is stopped?
7-10 days
When can neuraxial block be performed after TICLOPIDINE (TICLID) is stopped?
10 days
When can neuraxial block be performed after TICAGRELOR (BRILINTA) is stopped?
5-7 days
When can neuraxial block be performed after CANGRELOR (KANGREAL) is stopped?
3 hrs
When can neuraxial block be performed after ABCIXIMAB (REOPRO) is stopped?
24-48 hrs
When can neuraxial block be performed after TIROFIBAN (AGGRASTAT) is stopped?
4-8 hrs
When can neuraxial block be performed after EPTIFIBATIDE (INTEGRILIN) is stopped?
4-8 hrs
When can neuraxial block be performed after DIPYRIDAMOLE (PERSANTINE) is stopped?
24 hrs for ER formulation