Oropharynx and Larynx Flashcards
Often the _____ is a component
of a Upper Respiratory Infection (URI)
syndrome
pharyngitis
VIRAL PHARYNGITIS Etiology/Pathophysiology
○ Many different common viruses are known etiologic agents.
■ Rhinovirus (>100 different subtypes) - About 20% of cases
■ Adenovirus - Probably nearly as common as Rhinovirus
■ Epstein-Barr Virus - causal agent of Infectious Mononucleosis
● Will be discussed separately later
VIRAL PHARYNGITIS Clinical presentation
○ Throat pain/soreness
○ Nasal congestion
○ Fever, generally low-grade
○ Nonproductive cough is
common with URI syndrome
○ Hoarse voice is possible
Viral Pharyngitis Physical Exam
○ Edema and erythema of the
oropharynx
○ Scant exudate is possible
○ May see shallow vesicles
○ In URI, nasal mucosa
■ Erythematous
■ Rhinorrhea
○ Conjunctivitis sometimes
VIRAL PHARYNGITIS Diagnostic Evaluation
Generally, considered a clinical diagnosis based on H&P
■ Lab tests should be reserved for select cases based on suspicion.
○ Rapid testing available for some viruses
■ RSV, influenza
○ If H&P suggest it could be strep throat…
■ Strep testing could be considered
VIRAL PHARYNGITIS Management
○ Rest, time, reassurance, return precautions.
○ Hydration is very important!
○ Ibuprofen > Acetaminophen
■ Aspirin is not first choice
○ Topical anesthetics (gargles, lozenges)
VIRAL PHARYNGITIS Management IF Herpes simplex is the pathogen
■ Acyclovir or Valacyclovir can help
VIRAL PHARYNGITIS Management IF Influenza is the pathogen
■ Oseltamivir (Tamiflu) can help shorten duration of illness
If the patient has significant URI-associated nasal congestion, eustachian
tube dysfunction can result in _____
subsequent sinusitis and/or otitis media
Some patients with influenza may later develop secondary _____, which may then require antibiotic treatment
bacterial pneumonia
A common type of viral pharyngitis known as ____ is caused by the Epstein-Barr Virus (EBV)
Infectious Mononucleosis
(“mono”)
EBV is transmitted via intimate contact with ____
bodily secretions, primarily
oropharyngeal secretions (“kissing disease”)
Infection of B lymphocytes results in a humoral and cellular response with
EBV
EBV PHARYNGITIS History
○ Interestingly, most are actually
asymptomatic
○ Incubation period is 1-2 months
○ Fatigue.
○ Prolonged malaise.
○ Sore throat
EBV PHARYNGITIS Physical Exam
○ Early signs
■ Fever
■ Lymphadenopathy
● Commonly b/l Post Cervical
■ Pharyngitis
○ Later signs may include…
■ Hepatomegaly
■ Splenomegaly
■ Palatal petechiae
■ Jaundice (30% of elderly patients)
_____ is the most common confirmatory test in the presence of signs/symptoms of EBV pharyngitis
A rapid heterophile agglutination test (known commonly a Monospot test)
EBV PHARYNGITIS Management
○ Antibiotic treatment is not indicated.
○ Treatment approach is mostly the same as other viral pharyngitis.
■ Rest, hydration, NSAIDs, topical anesthetics
○ Patient education that symptoms of fatigue and malaise can persist for weeks or even months
○ Patients with extreme tonsillar
enlargement may be at risk of airway
obstructions. In this case, a short course of
steroids would be appropriate.
■ Ex: Prednisone PO for 5 days
Patients with extreme tonsillar
enlargement due to EBV may be at risk of airway obstructions. In this case, a short course of _____ would be appropriate
steroids
acute bacterial pharyngitis caused
by Group A Beta-Hemolytic Streptococci (GABHS)
STREPTOCOCCAL PHARYNGITIS
STREPTOCOCCAL PHARYNGITIS History
○ Rather sudden onset of sore throat
○ Fever, often high
○ Pain and difficulty with swallowing
○ “Swollen glands” in the neck
○ Usually no cough or rhinorrhea
STREPTOCOCCAL PHARYNGITIS Physical Exam
○ Oropharyngeal erythema and edema
○ Tonsillar exudate and swelling
■ Grayish white patchy exudate
○ Tender, enlarged anterior cervical lymph
nodes
○ Febrile
____ commonly accompanies strep throat
Scarlet fever
Scarlet Fever on H&P
Scarlet fever commonly accompanies strep throat.
■ Results from pyrogenic exotoxin released by GABHS
■ Scarlatiniform rash that blanches with pressure
■ Appears on the 2nd day of illness and fades within a week
■ Followed by extensive desquamation that lasts for several weeks
First line medication class for Strep is ____
Penicillin
● Penicillin VK or Amoxicillin for 10 days
● IM Bicillin (Penicillin G benzathine) x 1 is
also effective
Tx for strep if allergic to penicillins
■ Macrolides (azithromycin, clarithromycin)
■ Cephalosporins (cefdinir)
■ Clindamycin
When is a tonsillectomy warranted?
○ Surgical removal of the tonsils is a fairly common surgical procedure in
children and teens- Performed by ENT surgeon.
○ Generally reserved for those with recurrent cases.
■ 7 episodes of throat infection in 1 year OR
■ 5 episodes each year for 2 years OR
■ 3 episodes annually for 3 years
DIPHTHERIA Epidemiology
A form of bacterial pharyngitis cause by Corynebacterium diphtheria
● Uncommon the developed nations due to widespread immunization practices;
usually seen in those who are not fully vaccinated (TDaP and Td vaccines).