Organogenesis Flashcards

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1
Q

what is organogenesis?

A

organized integrated processes that transforms amorphous mass of cells into complete organ

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2
Q

what are the minimal requirements to build an organ?

A

self-organisation
cell adhesion
cell signalling

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3
Q

what is differential adhesiveness?

A

sorting out different cell types carrying different amounts of adhesion molecules on their surfaces
ingredient in organogenesis

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4
Q

describe the development of the liver bud

A

mesodermal BMP and FGF signalling specifies liver bud in foregut endoderm

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5
Q

what is an organoid?

A

multiple organ-specific cell types capable of recapitulating some specific function of the organ
grouped together and spatially organized similar to an organ

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