Organogenesis Flashcards
1
Q
what is organogenesis?
A
organized integrated processes that transforms amorphous mass of cells into complete organ
2
Q
what are the minimal requirements to build an organ?
A
self-organisation
cell adhesion
cell signalling
3
Q
what is differential adhesiveness?
A
sorting out different cell types carrying different amounts of adhesion molecules on their surfaces
ingredient in organogenesis
4
Q
describe the development of the liver bud
A
mesodermal BMP and FGF signalling specifies liver bud in foregut endoderm
5
Q
what is an organoid?
A
multiple organ-specific cell types capable of recapitulating some specific function of the organ
grouped together and spatially organized similar to an organ