Organizers Flashcards

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1
Q

Organizer that induces dorsal polarity…

A

Spemann’s organizer

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2
Q

Spemann’s organizer: the morphogen is…

A

chordin protein (toolkit gene & signaling protein)

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3
Q

Spemann’s organizer: location it acts during development is…

A

dorsal lip of the blastopore

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4
Q

Spemann’s organizer: induces…

A

dorsal polarity

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5
Q

Organizer that induces forelimb…

A

AER (apical ectoderm ridge)

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6
Q

AER: the morphogen is…

A

fgf-8 protein

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7
Q

AER: location it acts during development…

A

Hox 5/6 boundary

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8
Q

AER: induces…

A

arm below elbow (forelimb)

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9
Q

Organizer that induces fingers (not the thumb)…

A

ZPA (zone of polarizing activity)

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10
Q

ZPA: the morphogen is…

A

sonic hedgehog protein

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11
Q

ZPA: location it acts during development…

A

hand (pinky side)

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12
Q

ZPA: induces…

A

fingers (not the thumb)

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13
Q

The morphogen is always…

A

a protein

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14
Q

From the name alone, how can you tell if it is a gene?

A

genes are always uppercase (example: Sonic Hedgehog)

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15
Q

From the name alone, how can you tell if it is a protein?

A

proteins are always lowercase (example: sonic hedgehog)

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