organisation Flashcards
this is a massive topic, i'm so sorry
what are cells?
the basic building blocks of all living organisms.
what is a tissue?
a group of similar cells that work together to carry out a particular function.
- e.g. muscle cells form muscle tissue. they contract and relax to move different parts of the body.
what is an organ?
a group of different tissues that work together to carry out a particular function.
- e.g. epithelial, muscle, and glandular tissue all work together to form the stomach, which has the function of killing microorganisms and breaking down proteins.
what is the next step of organisation above organs?
organs are organised into organ systems, which work together to form organisms.
what are the three main nutrients in food, and how are they absorbed into the bloodstream?
- carbohydrates (e.g. starch), protein, and lipids (fats)
- all of these are large molecules and are too large to be absorbed into the bloodstream, and so have to be digested.
- enzymes break down these molecules into smaller molecules, which can then be absorbed into the bloodstream.
what is the pathway of food through the digestive system?
(this is a really massive flashcard with a lot of content on it, so if you don’t get it straight away, don’t worry, you will eventually)
- food is chewed in the mouth. amylase enzymes in the saliva begin to digest the starch into smaller sugar molecules.
- the food then passes down the oesophagus and into the stomach. in the stomach, protease enzymes begin the digestion of proteins. the food spends several hours in the stomach.
> the stomach also contains hydrochloric
acid, helping the digestion of large
molecules and killing bacteria.
> the churning action of the stomach
muscles turns the food into fluid,
increasing the surface area and making
it quicker for enzymes to digest. - the fluid now passes into the small intestine. the pancreas releases chemicals into the small intestine which continue the digestion of starch and protein. it also begins the digestion of lipids.
> the liver releases bile, which helps to
speed up the digestion of lipids. bile also
neutralises the acid released from the
stomach. - the fluid continues down the small intestine, and its walls release more enzymes to continue the digestion of protein and lipids.
> here, the small food molecules
produced by digestion are absorbed
into the bloodstream, either by diffusion
or active transport. - the fluid then makes its way into the large intestine, where water is absorbed into the bloodstream.
- the faeces is released from the body.
what are the different large molecules broken down into, and what are the names of the enzymes that break them down?
- carbohydrates (including starch) - simple sugars
CARBOHYDRASE (E.G. AMYLASE BREAKS
DOWN STARCH) - proteins - amino acids
PROTEASE
> proteins are long chains of amino
acids. in digestion, they’re broken down
into individual amino acids, and once
absorbed into the bloodstream, they’re
joined together in a different order to
make human proteins. - lipids (fats) - 1 molecule of glycerol attached to 3 molecules of fatty acids.
LIPASE
describe enzymes and how they work:
- enzymes catalyse chemical reactions.
- they are large protein molecules, with a groove on their surface called the active site.
- the active site is where the substrate attaches to - the substrate is the molecule that the enzyme breaks down.
describe the ‘lock and key’ theory:
enzymes are specific. the substrate must fit perfectly into the active site of the enzyme.
where are the different enzymes secreted?
amylase - salivary glands, pancreas
protease - stomach, pancreas, small intestine
lipase - pancreas, small intestine
describe bile:
- made in the liver, stored in the gallbladder.
- speeds up the digestion of lipids BUT is not an enzyme.
- bile emulsifies lipids, increasing the surface area of lipid droplets and increasing the rate of digestion by lipase.
- bile is alkaline. neutralises the acidic conditions (from hydrochloric acid) in the small intestine and the stomach. the alkaline conditions and large surface area increase the rate of lipid digestion by lipase.
what is the effect of temperature on enzymes?
- initially, the activity of the enzyme increases as the temperature increases - the enzyme and the substrate are moving faster, so there are more collisions per second between the enzyme and the active site.
- however, the enzyme will reach the optimum temperature (37 degrees celsius for more human enzymes). after this temperature has been surpassed, the activity of the enzyme rapidly decreased to 0.
- these high temperatures have denatured the enzyme, and the changed the shape of its active site. now the substrate doesn’t fit perfectly anymore, and enzyme can no longer catalyse the reaction.
what is the effect of pH on enzymes?
- the enzyme has an optimum pH, where the activity is maximum.
- if we make the pH more acidic or more alkaline, then the activity drops to 0, as the enzyme has denatured.
- each enzyme has a specific optimum pH. protease enzymes, for example, work best at an acidic pH.
how is the small intestine adapted to absorb the products of digestion into the bloodstream?
- very long. provides a large surface area for absorption of the products of digestion.
how are villi adapted to absorb the products of digestion into the bloodstream?
- the interior of the small intestine is covered with millions of villi, which increase the surface area for the absorption of molecules.
> the villi are covered with micro-villi,
increasing the surface area even more.
> villi have a good blood supply, so the
bloodstream rapidly removes the
products of digestion. this maintains a
high concentration gradient, and
increases the rate of diffusion/active
transport.
> very thin membrane, ensuring a short
diffusion path.
what is the structure and function of the heart?
function: an organ that pumps blood around the body in a double circulatory system.
structure:
- four chambers (left and right atrium, left and right ventricle). the atria are separated from the ventricles by valves.
- four main blood vessels.
> vena cava. brings deoxygenated
blood from the body.
> pulmonary artery. deoxygenated
blood passes from the heart to the
lungs.
> pulmonary vein. oxygenated blood
passes from the lungs to the heart.
> aorta. oxygenated blood pumped
from the heart to the body.
what is the path of blood through the heart?
- blood enters through the vena cava into the right atrium.
- the atrium contracts, forcing blood through a valve into the right ventricle.
- the blood is taken from the right ventricle, through the pulmonary artery, to the lungs, where it becomes oxygenated.
- the now oxygenated blood enters into the left atrium through the pulmonary vein.
- the atrium contracts again, forcing it through the valve into the right atrium.
- the blood is carried out of the right atrium and pumped into the body by the aorta.
what is the purpose of a valve in the heart?
prevents the blood from flowing back into the atria during contraction.
why does the left side of the heart have a thicker, muscular wall than the right side?
the left ventricle pumps blood around the entire body, so it needs to provide a greater force. the right ventricle only needs to pump blood to the lungs.
what are coronary arteries?
- branch out of the aorta and spread across the heart muscle.
- provides oxygen to the muscle cells of the heart (this oxygen is used in respiration to provide energy for contraction).
how is the natural, resting heartrate controlled?
controlled by a group of cells in the top of the right atrium, called the ‘pacemaker’.
- if the natural pace maker stops working, doctors can plant an artificial pacemaker, which corrects irregularities in the heart rate.
describe the lungs:
- provide an exchange surface adapted for:
- absorbing oxygen (for respiration) into the blood from the air.
- transferring carbon dioxide (produced by respiration) from the blood, into the lungs, then the air. - this transfer of gases is called gas exchange.
describe the structure of the respiratory system:
- adapted to allow air to pass in and out of the body, and to allow efficient gas exchange to occur.
- lungs enclosed in the thorax, protected by 12 pairs of ribs.
- ribs are moved by two sets of intercostal muscles.
- there is a muscular diaphragm beneath the lungs.
- the trachea branches into two bronchi. rings of cartilage in the walls of the lungs help to keep it open as air draws in.
- the bronchi split into smaller branches and then into smaller tubes called bronchioles - these all end in a cluster of microscopic air sacs called alveoli.
describe the process of gaseous exchange in the alveoli:
- occurs between the alveoli and the blood in the capillaries that supply the lungs. capillaries cover 70% of the outside of the alveoli, providing a large surface area for gases to diffuse across.
- each of the alveoli is a small sphere about 300 micrometres in diameter, giving it a large surface area : volume ratio. there are around 700 million alveoli. the total surface area of the alveoli is 70 square metres.
- blood flows from the heart across the alveoli, carbon dioxide diffuses out of the blood and into the alveoli, and oxygen diffuses out of the alveoli and into the blood - the blood then returns to the heart.