Organelles and Associated Diseases Flashcards
1
Q
A failure in what organelle causes Tay-Sach’s Disease?
A
Lysosome
2
Q
In Tay-Sach’s disease, what is wrong with the affected organelle that causes the accumulation of white material around the retina?
A
A lysosomal enzyme (β-hexosaminidase) deficiency allows for the accumulation of Gangliosides.
3
Q
In general, what type of symptom would you expect to see in any patient with a lysosomal storage disorder?
A
The accumulation of lipids, glycoproteins, or mucoplysaccharides that would normally be digested by a lysosomal enzyme.
4
Q
In a patient with Zeiweger syndrome, what organelle is not properly functioning?
A
The peroxisomes
