Oral topics Flashcards

1
Q

List the periods of the history of surgery! What were the milestones!

A

3 periods
I. From the primeval times until the middle of the 19th century
*Only removal of injured parts was used

II. From the discovery of narcosis (16.10.1846) until the 1960s
* Included not only removal of the injured parts, but also their reconstruction
* The milestone was the initiation and application of the principles of
asepsis and antisepsis, discovery of blood groups and the development of intensive therapy

III. Lasted from the 1960s until today
* The development of instruments, natural science, researchers, as well as technical development

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2
Q

When was the “Ether Day”? Who did and what on this day?

A

On October 16. 1846 Dr. William T. G. Morton anesthetized a patient with ethyl ether for
the first time

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3
Q

When and by whom was the chlorinated lime hand-­‐washing introduced? What were his
findings?

A

Ignaz Semmelweis 1847

Doctors went from autopsy to child-delivery, maternal mortality went from 30%→1%

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4
Q

Who created the “antiseptic theory”?

A

Joseph Lister

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5
Q

Who introduced the “antiseptic theory” in hungarian surgery?

A

Hümer Hütl

(note that Marius and Stine were wrong on this answer! Check the department book and you can find it. However, this question on the topic list has now changed to not include “in hungarian surgery,” so it’s not totally clear)

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6
Q

Name 4 surgical instruments which refer to doctors involved in the development of
surgery!

A
  1. Kocher clamp
  2. Lumnitzer clamp
  3. Hagar needle holder
  4. Péan clamp
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7
Q

What does the acronym “NOTES” mean?

A

NOTES

Natural Orifice Transluminal Endoscopic Surgery

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8
Q

What is the definition of surgical intervention?

A

A procedure performed on a living body usually with instruments for the repair of damage or the restoration of health and especially one that involves incision, excision, or suturing

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9
Q

What do the septic and aseptic operating theatres stand for?

A

In the septic operating room the infected parts of the body are operated (e.g. purulent wounds, gangrenes)

In the aseptic operating rooms the danger of bacterial infection does not usually exist (e.g. varicectomy)

(There is no need to build the aseptic operating room in a separate area; the two different types can even share a common corridor)

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10
Q

How shall the staff and the patient enter the operating room?

A

Before entering into the operating room you should change your clothes in the locker
room and wear the surgical cap and the face mask
Following this, you can enter into the surgical territory
The patients are brought into the operating room after passing through a separate locker
room

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11
Q

Describe the structure of the operating room!

A

The operating room is 50-70 m2 , and does usually not have any windows
It is lighted and its walls are covered with light-colored tiles up to the ceiling
There is artificial ventilation and air-conditioning
The operating complex must be architecturally separated from the wards and the intensive care unit, but should be in the vicinity of the ICU

The complex consists of:

  • Locker rooms
  • Scrub-­‐up area
  • Preparing rooms
  • Operating theatres

The walls and floor of the operating room have no gaps, so they can be cleaned easily (antiseptic gap-­‐free floors)
The doors are automatic, and the rooms are equipped with central and portable vacuum systems, as well as pipes for gases

Main layout:
Operating lamp, operating table, Sonnenburg’s table, supplementary instrument stand, kickbucket, suction apparatus, diathermy, microwave oven, portable X-ray, anesthesia machine, and other instruments required during anesthesia

The central supply of electricity is automatically connected to batteries

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12
Q

List 8 equipments /instruments within the operating room!

A

Operating lamp, operating table, Sonnenburg’s table, supplementary instrument stand,
kick bucket, suction apparatus, diathermy, microwave oven, portable X-ray, anesthesia
machine, and other instruments required during anesthesia

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13
Q

Explain the rules of behaviour in the operating room!

A

1) Only those people whose presence is absolutely necessary should stay in the OR
2) Activity causing superfluous air flow (talking, laughter, or walking around) should be avoided

3) Entry into the OR is allowed only in operating room outfit and shoes worn exclusively in the OR
a. This complete change to the clothes used in the OR should also apply for the patient placed in the holding area (i.e. locker room)

4) Leaving the OR in surgical outfit is forbidden
5) The doors of the OR must be closed
6) Movement into the OR out of the holding area (locker room) is allowed only in a cap and mask covering the hair, mouth, and nose

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14
Q

Describe the general rules of the aseptic operating room!

A

Only sterile instruments can be used to perform a sterile operation

Only Sterile personnel can handle sterile equipment

Instruments which are located below the waist arenot considered sterile

If a sterile instrument comes in contact with aninstrument of doubtful sterility, it will lose its sterility

The edges of boxes and pots can not be considered sterile

A surgical area can never be considered sterile
However, the applications of aseptic rules of operations are mandatory

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15
Q

Explain the definition of asepsis!

A

Includes all the procedures, activities and behaviors designed to keep away the microorganisms from the patient’s body and the surgical wound

In other words, the purpose of asepsis is to prevent contamination (maintain sterility)
In a wider sense, asepsis means such an ideal state when the instruments, the skin, and the surgical territory do not contain microorganisms (prevention)

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16
Q

Explain the definition of antisepsis!

A

Includes all those procedures and techniques designed to eliminate contamination (bacterial, viral, fungal) present on objects and skin by means of sterilization and disinfection

Because skin surfaces and so the operating field and the surgeon’s hands cannot be considered sterile, in these cases we do not talk about superficial sterilization

In a wider sense, antisepsis includes all those prophylactic procedures designed to ensure surgical asepsis (treatment)

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17
Q

How to prevent the evolution of postoperative wound infections before the surgery?

A

Careful scrub and preparation of the operative site (cleansing and removal of hair) is necessary

Wearing sterile clothes in the OR

Knowledge and control of risk factors (e.g. normalization of the serum glucose level in case of diabetes mellitus)

In septic and high-­‐risk patients: perioperative antibiotic prophylaxis

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18
Q

How to prevent the evolution of postoperative wound infections during the surgery?

A

Appropriate surgical techniques must be applied

Change of gloves and rescrub if necessary

Optimize body temperature of the patient

Narcosis may worsen thermoregulation
Hypothermia and general anesthesiabothinduce vasodilation, and thus the core temperature will decrease

The oxygen tension must be maintained

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19
Q

How to prevent the evolution of postoperative wound infections after the surgery?

A

Wound infection generally evolves shortly (within 2 hours) after contamination

Hand washing is mandatory and the use of sterile gloves is compulsory while handling wound dressings and changing bandages during postoperative care

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20
Q

What is the definition of sterilization!

A

To sterilize means to kill all microorganisms and spores to create a germ-­‐free environment

Methods:
o Autoclave (steam with high pressure)
o Gas sterilization with ethylene-­‐dioxide
o Cold sterilization with sprecide chemicals
o Gamma and electron radiation
o Plasma sterilization (low temperature
hydrogenperoxidegasplasma - effect of free radicals)

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21
Q

What is the definition of disinfection!

A

The aim is to decrease the number of or inactivate live microbes

Methods:
o Low temperature steam
o Chemical disinfectants (phenol, chloride containing compounds, alcohols)
Surgical hand-scrubbing is considered a disinfectingprocedure.

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22
Q

Explain the steps of the two-­‐phase surgical hand scrub!

A

1st Phase: Mechanical cleansing
o Wash the hands and forearms thoroughly with soap and warm water
o The first phase has no time limit, only until we are satisfied
o Make sure to wash off all the soap, the disinfectant used in phase two is not
supposed to foam, so if during phase 2 foam appears on your hands, you have not
washed properly in phase 1 and will lose points
o Use tissue paper to dry carefully

2nd phase: Disinfectant phase 
o Disinfectant hand scrub should be rubbed on your hands 5 x 1 min 
o The disinfectant area should extend to the elbow and get shorter and shorter for 
each scrub 
1st time: Whole forearm
2nd time: 2/3 of the forearm 
3rd time:  1/2 of the forearm 
4th time: 1/3 of the forearm 
5th time: only hands and wrists
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23
Q

What is the purpose of isolation? How do we do it?

A

After skin preparation the operating area must be isolated from the non-­‐disinfected skin surfaces, and body areas by application of sterile linen textile or sterile water proof paper drapes

The main aim is to prevent contamination from the patients skin
It is generally done with the help of 4 pieces
The scrub nurse and the assistant use a special specially folded first, big sheet to isolate the patient’s legs
The second, horizontal sheet is used to isolate thehead, and is fixed to the guard
Placement of the two sided sheets then follows
The isolated area is always smaller than thescrubbed area
4 Backhaus towel clips will fix the isolating sheets

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24
Q

List the basic surgical instrument groups!

A
  1. Cutting and dissecting instruments
  2. Grasping, clamping and occluding instruments
  3. Hemostatic instruments
  4. Refracting and exposing instruments
  5. Wound-­‐closing instruments and material
  6. Special instruments
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25
What  is  the  function  of  the  dissecting  instruments?  List  some  of  these  dissecting instruments!
Their  function  is  to  cut  or  dissect  the  tissue  and  remove  the  unnecessary  tissues  during surgery Scalpel Scissors (straight/curved blunt/sharp) Hemostats used for tissue preparation (can be dissecting, grasping, or hemostasis) Dissector Diathermy  knife Ultrasonic  cutting  device CUSA  (cavitron  ultrasonic  surgical  aspirator) LASER  (light  amplification  by  stimulated  emission radiation) Amputating  knifes,  saws  and  raspatories
26
Explain  the  use  of  electric/diathermy  knife!  What  kind  of  diathermy  knifes  do  you  know?
Dissects  tissue  with  the  help  of  heat  which  is generated  by  electrical  current During  the  dissection  the  heat  can  also  coagulate  the  blood  from  vessels,  giving  it  a strong advantage  by  cutting  and  hemostasis simultaneously They  can  be  either  mono- or  bipolar Bipolar:  the  electric  current  is  passing  between  two  parts  of  the  instrument e.g.  bipolar  forceps * There  is  a  need  for  smaller  voltage  and amperages  making  it  possible  to perform  more  precise  work  and  smaller  size  of  burned  area Monopolar:  the  electric  current  is  passing  between  the  instrument  and  an indifferent  electrode  placed  beneath  the  back  or  one  of  the  limbs  of  the patient  e.g.  electrocauter  or  electrocautery  knife More  common  in  general  surgery (OBS: pacemakers)
27
Is  it  accepted  to  use  electric  knife  on  patients  with  pacemaker?
regarding monopolar electric knives In  patients  with  old  pacemakers  the  electrical  current  may  cause  arrhythmias,  and  it must  therefore  be  adjusted  prior  to  surgery
28
What  do  you  know  about  the  ultrasonic  cutting  device?
Ultrasonic  cutting  device  (Ultracision)  is  using ultrasound  to  cut  and  coagulate  the tissues It  is  working  similarly  to  the  diathermy  but  it  does  not  cause  thermic  injury It  makes  possible  to  have  more  precise  movements  during  surgery
29
Name  the  non‐locking  grasping  instruments!  Explain  their  functions!
``` The  non-­‐locking  grasping  tools  are  the  Thumb  forceps A. Smooth forceps B. Toothed forceps C. Splinter forceps D. Ring forceps (brain tissue forceps) E. Dental forceps ``` o The  simplest  form  of  grasping  tools  made  of  different  sizes o They  can  have  blunt  (smooth),  sharp  (splinter)  or  ring  tips o They  are  used  to  hold  tissue  during  cutting  and  suturing o The  smooth  forceps  is  also  called  anatomical  forceps,  the  toothed  forceps  is  also called  surgical  forceps  and  the  splinter  forceps  is  also  called  ophthalmic  forceps o The  forceps  should  be  held  like  a  pencil,  compressed  between  the  thumb  and index  finger o For  holding  skin  and  subcutaneous  tissue  the  toothed  forceps  is  most  used o For  holding  of  sponges,  bandages,  vessels  and  hollow  organs  use  the  anatomical forceps o The  forceps  is  not  suitable  for  long  continuous  grasping  and  the  tissue  graspers should  be  used  for  this  purpose
30
List  organ  clamps!
These  are  instruments  used  for  delicate  grasping  and  holding  of  the  organ 1. Klammer intestinal  clamp, 2. Gallbladder  clamp 3. Babcock  forceps (gallbladder) 4. Allis  clamp (lungs)
31
List  the  hemostatic  instruments!  Explain  their  functions!
Vascular  clamps  (Péan,  mosquito,  abdominal  Péan,  Kocher,  Lumnitzer,  Satinsky, bulldog), Electrocautery  knife,  various  ligation  needles  and  directing  probes  (e.g. Deschamp  ligation  needle,  and  Payr  probe),  and  argon  beam  coagulator
32
List  the  retracting  instruments!  Explain  their  functions!
Retractors  are  sued  to  hold  tissues  and  organs  aside  during  surgery  in  order  to  improve the  exposure,  visibility  and  accessibility   Hand-­‐held  retractors o Skin  hook,  rake,  Roux,  Langenback,  visceral  and abdominal  wall  retractors o Held  by  assistant o Cause  minimal  tissue  damage  because  tension  is maintained  only  for  as  long  as necessary Self-­‐retaining  retractors o Weitlaner  self-­retaining  retractor,  Gosset  self-retaining  retractor o Of  great  help  when  applied  correctly o Damage  to  tissues  can  occur  if  not  used  carefully  when  placed  and  removed
33
Explain  the  application  area  of  metallic  clips!
The  Michel  clips  can  be  used  with  the  help  of  a  Michel  clip  applicator  or  remover They  are  used  to  close  a  skin  wound  and  any  luminal  structure,  vessel,  duct  etc. Other  uses: In  the  wound  stapler  making  it  possible  with  atraumatic  and  fast  wound  closure In  hemostasis  (can  occlude  lumen) As  a  marker  because  it  can  be  seen  on  the  X-­‐ray  (e.g.  bed  of  a  tum0er
34
What  do  you  know  about  the  CT  and  MRI  examination  of  patient  carrying  metalic  clips?
CT:   The  clip  disturbs  the  picture  only  in  the  vicinity  of  it  and  so  examination  can  be  done MRI: The  clips  make  it  impossible  to  perform  the  examination  because  these  metals can  move  in  the  magnetic  field The  clips  can  become  wandering  within  the  body Due  to  this  it  has  become  more  common  to  use  the  non-­‐magnetic  clips  like titanium,  platinum  and  absorbable  clip
35
What  is  the  Steri-­Strip?  When  to  use  it?
Usually  produced  from  fibrin,  collagen  or  thrombin  and  induces  the  last  phase  of  blood coagulation  producing  fine  fibrin  mesh Application o Hemostasis  in  operations  done  on  solid  organs o Close  the  place  of  air  leakage  in  lung  surgeries o Wound  closure Disadvantage:  can  increase  the  degree  of  infection  in  infected  wounds  and  lead  to abscess  formation
36
List  special  instruments!
Volkmann  curette Main  application: *Skin  tags,  e.g.  condyloma,  warts,  removal *Clean  the  base  of  the  infected  wound *Remove  infected  bone  in  case  of  osteomyelitis Round-­‐ended  probe Use  to  gauge  depth  or  direction  of  a  sinus  or  cavity   Payr  clamp (crushing) Use  it  before  resecting  the  intestine Suction  set X-­‐raying  set The  metallic  screws  and  pins,  joint  prosthesis,  hernial  meshes,  vascular  grafts and  silicon  implants
37
Describe  the  conventional  (close-­eye,  French-­eyed)  needles!
Needs  to  be  threaded The  needle  and  two  arms  of  the  thread  goes through  the  tissue Danger  of  untying Re‐sterilization
38
Describe  the  atraumatic  needles!
Has  less  thickness  going  through  tissue  due  to  no  arms  of  the  thread,  resulting  in  less tissue  damage The  thickness  of  the  thread  is  slightly  thicker  than  the  whole  made  by  the  needle,  making the  tissue  pack  around  the  thread  and  avoiding  leakage -No  threading  time -No  re-­sterilization -­No  danger  for  corrosion  and  untying -­Be  careful  to  not  pull  to  hard,  the  thread  may  detach  from  the  needle
39
What  are  the  main  groups  of  the  circular  needles?
Has  3  main  groups;  taper-­point,  taper‐cutting  and  blunt  tape -­Circular  needle  classically  refers  to  taper-­‐point  circular  needle Both  the  tip  and  the  body  of  the  needle  are  circular. The  needles  are  so  thin  that  they  separate  tissue  fibers  without  cutting  them They  are  generally  used  in  easily  penetrable  tissue,  like  peritoneum,  abdominal  organs, myocardium,  and  subcutaneous  tissue At  the  tip  of  the  taper-­‐cutting  needle  there  are  3  cutting  edges - ­The  edges  gradually  becomes  more  flattened  and  are  finally  obliterated  at  the  body - ­They  are  developed  to  sew  sclerotic,  scarred  and  classified  tissues - ­The  diameter  caused  by  the  needle  is  smaller  than  the  thread The  blunt  taper  needles  have  a  circular  body  and  a  blunt  end It  serves  to  prevent  the  danger  of  needle  stick  and  is  used  a  lot  in  patients  with  HIV  or hepatitis The  tissues  are  pushed  aside  and  no  separating  in  their  structure  is  caused
40
Explain  the  difference  between  conventional  and  reverse  cutting  needles!
In  the  conventional  needle  the  third  edge  is  facing  the  internal  part  of  the  curving  body In  the  reverse  needle  the  third  edge  is  facing  the  external  part  of  the  curving  body
41
What  are  the  main  characteristics  of  the  surgical  suture  materials?
Physical:  caliber,  tensile  strength,  elasticity,  capillarity,  structure,  water absorbent  capacity,  sterilizability Application  properties:  flexibility,  capability  to  slip  in  tissue,  knotting  properties, knot  security Biological  properties:  absorbent  capacity
42
What  are  the  advantages  and  disadvantages  of  natural  and  synthetic  suture  materials?
Natural  materials  have  good  knotting properties  and  are  easy  to  handle The  main  disadvantage  with  natural substances  is  that  they  contain proteins,  which  our  immune  system  will  target  as  non-self They  are  absorbed  by  macrophages  and  other  phagocytic  cells  leading  to  a  strong inflammatory  response Most  synthetic  materials  cause  only  small  reactions  in  the  living  tissues Their  absorbance  is  done  by  hydrolysis  and  there will  be  no  cellular  response  and  tissue  damage  
43
What  does  the  term  “thread  memory”  stand  for?
Thread  memory  is  the  capacity  of  the  suture  thread  to return  to  its  former,  packaged  shape (monofilaments have thread memory)
44
What  are  the  advantages  of  monofilament  threads?
``` Smooth surface Smaller friction Smaller resistance Smaller tissue injury No spreading of bacteria No capillarity Not transporting the tumor cells ```
45
What  are  the  disadvantages  of  multifilament  (twisted  or  braided)  threads?
``` Stretching Tissue drag,serrating Tissue trauma Spreading of bacteria Capillarity Transporting the tumor cells ```
46
Which  one   is  better:  monofilament  or  multifilament  thread?
Monofilament  due  to  less  disadvantges,  less  tissue,  trauma,  no  spread  of  abcteria  and  no spread  of  oncotic  cells
47
Describe  the  enzymatic  and  hydrolytic  absorption  processes  of  suturing  materials!
Enzymatic  is  active  and  done  by  cellular  elements,  it  is  characteristic  for  natural  suture materials The  result  can  be  severe  tissue  reaction  and  activation  of  the  inflammatory  processes   The  hydrolysis  is  passive  and  done  without  participation  of  cellular  elements   It  is  characteristic  for  synthetic  suture  materials The  chemical  and  physical  bonds  located  between  the  thread  fibers  will  become  loose, disintegrating  the  thread,  which  will  be  excreted
48
What  do  you  know  about  the  size  classification  of  the  suturing  materials?
The  USP  (United  States  Pharmacopoeia) is used here in Hungary It  groups  the  suture  materials  I  groups  based  on  thickness Thinnest: 11/0 (= 0,01 - 0,019 mm) Thickest: 7 (1.0 - 1,09 mm) Metric system: Thinnest: 0,1 (= 0,01 - 0,019 mm) Thickest: 10 (1.0 - 1,09 mm) (christ the americans are retarded)
49
What  do  you  know  about   the  simple  interrupted  suture?
Frequently  used  to  suture  skin,  fascia  and  muscle After  each  stitch,  a  knot  is  tied All  sutures  must  be  under  equal  tension The  advantage  is  that  the  remaining  sutures  still ensure  an  appropriate  closure  and  the  wound  will  not  open  if  one  suture  breaks  or  is removed The  disadvantage  is  that  it  is  time-­consuming  since  each  individual  suture  must  be knotted  
50
What  do  you  know  about   the  vertical  mattress  suture?
It  is  a  2-­row  skin  suture It  consists  of  a  deep  suture  that  involves  the  skin  and  the  subcutaneous  layer  (which closes  the  wound)  and  of  a  superficial  back  stitch  placed  into  the  wound  edge  (this approximates  the  skin  edges) The  two  stitches  are  in  a  vertical  plane  perpendicular  to  the  wound  line
51
Where  do  we  use  the  simple  continuous  suture  line?
This  can  be  applied  to  suture  tissues  without  tension,  the  wall  of  internal  organs,  the stomach,  the  intestines,  and  the  mucosa
52
Where  do  we  use  the  purse-­sting  suture?
The  openings  of  the  GI  tract  (e.g.  in appendectomy)  are  closed  by  this  suture An  atraumatic  needle  and  thread  are  used It  is  a  suture  for  a  circular  opening,  running continuously  around  the  opening   The  wound  edges  are  then  inverted  into  the opening  with  dressing  forceps  and  the threads  are  pulled  and  knotted  
53
When  it  is  suggested  to  remove  the  stitches?  What  are  the  influencing  factors?
After  careful  disinfection  of  the  wound,  the  suture  is  grasped  and  gently  lifted  up  with  a thumb  forceps The  thread  should  be  cut  as  close  to  the  skin  as  possible  so  that  no  thread  which  was outside  the  skin  can  be  pulled  through  the  wound This  way,  infection  of  the  wound  can  be  avoided
54
What  is  a  wound?
A  wound  is  a  circumscribed  injury  which  is  caused  by  an  external  force,  and  it  can involve  any  tissue  or  organ It  can  be  mild,  severe,  or  even  lethal can  be  divided  into: o Simple wounds In  simple  wounds,  skin,  mucous  membrane,  subcutaneous  tissue, superficial  fascia,  and  the muscles  (partially)  can  be  injured o Compound  wounds In  compound  wounds,  there  are  additional  injury  to  the  muscles,  tendons, vessels,  nerves  or  bones o Acute  or  chronic  wounds
55
What  areas  are  injured  in  case  of  a  simple  wound?
Skin,  mucous  membranes,  subcutaneous  tissue,  superficial  fascia,  and  the  muscles (partially)
56
What  areas  are  injured  in  case  of  a  compound  wound?
The  components  of  the  simple  wound  +  additional  injury  to  the  muscles,  tendons, vessels,  nerves  or  bones
57
What  kind  of  wounds  do  you  know  based  on  their  origin?
``` Mechanical Chemical Wounds  caused  by  radiation Wounds  caused  by  thermal  force Special  wounds ```
58
List  the  wounds  of  mechanical  origin!
``` Abraded  wound  (vulnus  abrasum) Punctured  wound  (v.  punctum) Incised  wound  (v.  scissum) Cut  wound  (v.  caesum) Crush  wound  (v.  contusum) Torn  wound  (v.  lacerum) Bite  wound  (v.  morsum) Shot  wound  (v.  sclopetarium) ``` fucking latin piece of shit
59
What  do  you  know  about  the  incised  wound?
vulnus scissum Caused  by  a  sharp  object Best  healing  of  all  the  wounds
60
What  do  you  know  about   the  shot  wound?
vulnus  sclopetarium Consists of an aperture, a slot tunnel and a possible output. If  the  shot  is  close  (e.g.  contact  shot),  burn  injury may be  present Caused  by  foreign  materials  which  may  remain  in  the  patient
61
Classify  the  wounds   according  to  bacterial  contamination?
Clean - Normal skin flora, no inflamm Clean-­contaminated - endogenous or environment, the surgical team, or the patient’s skin surrounding the wound. Contaminated - (significant bacterial contamination): Dirty wounds - the contamination comes from an established infection. Examples include: residual nonviable tissues and chronic traumatic wounds.
62
What  does  the  primary  wound  managements  stand  for?
Surgical wound closure can be performed if maximum 12 hours is passed since the time of injury. – cleaning, – anesthesia, – excision (< 6–8 h, exception: face, hand),
63
What  does  the  term  „primary  delayed  suture”  stand  for?
In the following cases, after clearing of the wound and washing it with physiologic saline solution cover it with a sterile bandage and put it in rest. Four to six days later, you can apply the delayed sutures. – signs of inflammation, – the wound is strongly contaminated, – the removal of the foreign body was not successful, – shattered wounds with blind spaces, – injuries of persons with especial jobs (e.g. surgeon, butcher, veterinarian, pathologist), and – bite, shot, and deep punctured wounds. Need to do: cleaning + covering and after 3-8 days delayed primary wound closure.
64
What  is  the  „early  secondary  wound  closure”?
If following the first management of the wound, the excised wound -after inflammation and necrosis- starts to proliferate, then there is a need to refresh the wound edges. 2 weeks after the injury: anesthesia, excision (refreshment of the wound edges), suturing, and draining.
65
What  is  the  „late  secondary  wound  closure”?
The proliferating former wound parts and scars should be excised. With greater defects, plastic surgery solutions should also be considered. 4–6 weeks after the injury: anesthesia, excision (of the secondarily healing scar), suturing, and draining.
66
What  holding  positions  of  the  scalpel  do  you  know?
The  fiddle-­‐bow  holding  grip,  used  for  long,  straight  incisions   The  pencil  grip,  used  for  short  or  fine  incisions  
67
Describe  the  phases  of  wound  healing!
Hemostasis-­‐inflammation  (0‐2  days) Granulation-­‐proliferation  (3-­‐7  days) Remodeling  (lasts  from  day  8 →  months)
68
What  is  happening  in  the Hemostasis-­‐inflammation phase  of  wound  healing?
Initial  vasoconstriction The  wound  fills  with  blood  clot  and  platelet aggregates,  and  fibrin  production develops Signs  of  inflammation  are  present Blood  flow  increases,  macrophage  and  leukocyte  mediators  (pro-­‐inflammatory cytokines  and  growth  factors)  are  released ``` The  cytokines  promote: Angiogenesis Fibroblast-­‐,  T-­‐,  and  B-­‐cell  activation Keratinocyte  activation Wound  contraction Removal  of  bacterial  components ```
69
What  is  happening  in  the  granulation-­‐proliferation  phase  of  wound  healing?
Formation  of  granulation  tissue  and  fibroblasts Fibroblast  migration  à  collagen  deposition Angiogenesis Granulation  tissue  formation Epithelization Contraction
70
What  is  happening  in  the  remodeling  phase  of  wound  healing?
Regression  of  many  capillaries Physical  contraction  (by  myofibroblasts) Collagen  degeneration  and  synthesis  –  the  fibers  become  smaller  and  stronger New  epithelium  is  produced The  final  tensile  strength  of  the  wound  is  ∼80%  of  the  initial  strength  of  the  tissue
71
Describe  the  types  of  wound  healing!
Healing  by  primary  intention: The  wound  edges  are  brought  together  so  that they  are  adjacent  to  each  other Minimizes  scarring Most  surgical  wounds  heal  by  primary  intention Healing  by  secondary  intention: The  wound  is  allowed  to  granulate  –  the  wound  may  be  packed  with  a  gauze The  tissue  loss  is  compensated  by  granulation  tissue  „according  to  the second  potential  goal  of  the  doctor” Due  to  abacterial  or  purulent  inflammation,  the  wound  is  filled  with  connective tissue  which  transforms  into  scar  tissue Compared  to  healing  by  primary  intention: Larger  clot  is  formed Inflammation  is  more  intense  because  there  is more  necrotic debris,  exudate  and  fibrin  to  remove Larger  amounts  of  granulation  tissue  due  to  larger  defect Involves  wound  contraction Healing  by  tertiary  intention The  wound  is  initially  cleaned  and  observed,  typically  4-­‐5  days  before  closure The  wound  is  purposely  left  open Examples:  healing  of  wounds  by  use  of  tissue  grafts
72
List  the  influencing/delaying   factors  of  wound  repair!
``` Local  factors: o Ischemia o Infection o Foreign  bodies o Edema,  elevated  tissue  pressure ``` ``` Systemic  factors: o Age  and  gender o Sex  hormones o Stress o Ischemia o Diseases  (e.g.  DM) o Obesity o Medication  (e.g.  glucocorticoids  and  some  antibiotics) o Alcoholism  and  smoking o Immunocompromised  conditions o Nutrition ```
73
What  early  complications  of  wound  healing  do  you  know?
``` Seroma Hematoma Wound  disruption Superficial  wound  infection Deep  wound  infection Mixed  wound  infection ```
74
What  are  the  characteristics  of   the  seroma?
The  wound  cavity  is  filled  with  serous  fluid,  lymph,  or  blood Signs:  fluctuations,  swelling,  redness,  tenderness,  subfebrility
75
What  are  the  characteristics  of  the  hematoma?
Occurs  due  to  insufficient  bleeding  control,  short  draining  time,  or  anticoagulant  therapy Signs:  swelling,  fluctuations,  pain,  redness
76
What  are  the  characteristics  of  the  wound  disruption?
Subdivided  into  partial,  superficial  (dehiscence),  and  complete  separation  (disruption) First,  the  deeper  layers  are  involved  and  finally  the  skin Can  be  caused  by  surgical  error,  increased  intra‐abdominal  pressure,  wound  infection,  or hypoproteinemia
77
What  forms  of  superficial  wound  infection  do  you  know?
Diffuse:  a  diffuse  and  superficially  spreading inflammation  located  below  the  skin o E.g.  erysipelas  and  lymphangitis  (caused  by  hemolytic  streptococci) Localized:  localized  (circumscribed)  infection   o E.g.  abscess
78
List  the  local  and  general  symptoms  of  wound  infection!
Local  signs: o Rubor,  tumor,  calor,  dalor,  and  functio  laesa General  signs: o Rapid  sedimentation  rate  of  RBCs,  leukocytosis,  fever,  shivering,  depression
79
What  are  the  late  complications  of  wound  healing?
``` Hypertrophic  scars Keloid Necrosis Inflammatory  infiltration Abscesses Foreign  body-­‐containing  abscesses ```
80
What  are  the  characteristics  of  hypertrophic  scar?
Hypertrophic  scars  develop  in  areas  of  thick  chorium They  are  composed  of  non-­hyalinic  collagen  fibers  and  fibroblasts,  and  are  confined  to the  incision  line They  usually  regress  spontaneously  within  1-­‐2  years
81
What  are  the  characteristics  of  keloids?
Keloids  are  over-­‐proliferations  of  collagen  fibers  in  the  subcutaneous  tissue They  have  well-­‐defined  edges,  with  pinkish-­‐brown,  emerging  tough  structures They  particularly  affect  scars  o  the  presternal  and  deltoid  areas,  and  the  ear They  are  characterized  by  subjective  complaints  (e.g.  pain,  itching)  and  constant development
82
What  is  hemostasis  and  what  are  the  factors  of  it?
Hemostasis  is  the  process  which  causes  bleeding  to  stop -­‐ Factors: o Vascular  hemostasis  (vasoconstriction) o Platelet  hemostasis o Clotting what the actual fuck is this question
83
What  are  the  characteristics  of  diffuse  bleeding?
Oozing  of  blood  from  bare  (denuded)  or  cut  surfaces  (can  become  serious  if uncontrolled) o Capillary  bleeding o Parenchymal  bleeding
84
What  could  be  the  direction  of   bleeding  from  clinical  point  of  view?  
External  (e.g.  by  trauma  or  surgical  incision, resulting  in  visible  bleeding) Internal: Internal (e.g. urinary tract: hematuria, respiratory tract: hemoptoa, GIT: hematochezia or melena). Body cavities (intracranial hemorrhage, hemothorax, hemascos, hemopericardium, and hemarthros), Among tissues (e.g.hematoma and suffusion).
85
What  methods  of  surgical  haemostasis  do  you  know?  
Mechanical   Thermal Chemical Biological
86
List  the  mechanical  methods  of   surgical  haemostasis!
Digital  pressure  (direct  pressure) Tourniquet  (constricting  or  compressive  device,  specifically  a  bandage) Ligation Suturing Preventive  hemostasis  (occurs  in  ligatures) Clips Bone  wax
87
List  haemostatic  methods  based  on  thermal  effects!
Low  temperature: o Hypothermia o Cryosurgery ``` High  temperature: o Electrocauterization o Monopolar  diathermy o Bipolar  diathermy o Laser  surgery o Local  electrosurgery ```
88
What  are  the  mechanisms  of  haemostasis  based  on  chemical  and  biological  materials? List  3  materials!
Mechanisms: o Vasoconstriction  (e.g.  epinephrine,  oxytocin) o Coagulation  (microfibrillar  collagen,  thrombin) o Hygroscopic  effect  (absorbable  collagen,  absorbable  gelatin,  oxidized  cellulose)
89
Give  examples  of  vital,  absolute,  and  relative  indications!  
``` Vital  indications: o Ruptured  aortic  aneurysm Absolute  indications: o Mechanical  ileus,  ebolectomy Relative  indications: o Hernia  repair ```
90
What  are  the  components  of  surgical  risk?  
Risk  of  surgery  itself  +  anesthesiological  risks Low-risk surgery:(e.g. inguinal hernia repair), where the expected blood loss is less than 200 ml. Medium-risk surgery: (e.g. colon resection), where the expected blood loss is less than 1000 ml) High-risk surgery: Extended abdominal and thoracic operations (e.g. liver and lung resections). blood loss exceeds 1000 ml.
91
What  factors  increase  surgical  risk?  
Acute  surgery -­‐ Duration  >  2  hours -­‐ >  65  years  old -­‐ Pregnancy -­‐ Malignant  diseases -­‐ Malnutrition -­‐ Alcohol  consumption -­‐ Smoking -­‐ Acute  disturbances  (hypovolemia,  dehydration,  shock) Acute  inflammations  (respiratory,  urinary,  GI,  sepsis) -­‐ Thrombosis -­‐ Acute  organ  insufficiencies  (heart,  lung,  kidney,  liver) -­‐ Acute  endocrine  disorder -­‐ Organ  insufficiencies  (heart,  lung,  kidney,  liver) -­‐ Endocrine  disorder -­‐ Immunological  disorders -­‐ Hemophilia -­‐ Organ  alterations  (see  below) -­‐ Chronic  disorder  (hypovolemia,  anemia) -­‐ Chronic  inflammations  (respiratory,  urinary,  GI) -­‐ Allergy
92
What  kind  of  organ  alterations  increase  surgical  risk?  
``` Cardiorespiratory Hypertension Nervous  system  alterations Diabetes  mellitus Chromic  uremia Cirrhosis Susceptibility  for  infection Immunosuppression Thromboembolic  predisposition ```
93
In  what  way  does  overfeeding   increase  surgical  risk?
Respiratory  disturbance  (usually  restrictive): o Deteriorating  the  gas  exchange,  increased  respiratory  function -­‐ Decreased  cardiac  reservoirs -­‐ Difficulty  with  intubation  (regurgitation) -­‐ Disturbances  with  wound  healing -­‐ Thromboembolism
94
List  the  organs  and  systems  whose  preoperative  examination  is  essential  from  the  point of  view  of  the  assessment  of  surgical  risk!  
Cardiovascular  system - ­‐ Respiratory  system - ­‐ Metabolic  state - ­‐ Renal  function - ­‐ Liver  function - ­‐ Endocrine  balance - ­‐ Homeostasis - ­‐ Immune  system
95
What  can  be  applied  for  trombosis  prophylaxis  during  pre‐,  and  postoperative  phase?
Drugs: o Heparin  derivatives  (Na-­‐heparin,  Ca-­‐heparin,  low  molecular  weight  heparins) o Platelet  aggregation  inhibitors  (e.g.  Aspirin,  Colfarit) ``` Physical: o Early  mobilization o Compression  (elastic  bandages) o Bed­‐side  bicycle o Keeping  the  lower  extremities  at  a  high  level ```
96
List  the  forms  of  vertical   laparotomy!  
``` Medial  laparotomy Paramedian  laparotomy Vertical  transrectal  laparotomy Pararectal  laparotomy Inguinal  transmuscular  laparotomy ```
97
List  the  forms  of  transverse  and  oblique  laparotomy!  
Transverse: o Horizontal  transrectal  laparotomy o Pfannenstiel suprapubic Oblique: o McBurney  incision o Paracostal  (Kocher)  laparotomy o Subcostal  laparotomy
98
What  abdominal  approaches  would  you  suggest  in  case  of  open  cholecystectomy, appendectomy,  or  gynecological  surgery?  
Open  cholecystectomy: o Right  paracostal  laparotomy Appendectomy: o McBurney  incision Gynecological  surgery: o Lower  median  muscle-­splitting  incision  (Pfannenstiel  incision)
99
What  do  you  know  about  the  muscle-­‐splitting  incisions?  What  are  the  advantages  and disadvantages?
In  these  types  of  incisions  the  fibers  of  the  abdominal  wall  muscles  are  not  cut  but separated  from  each  other  alongside  their  courses Advantage: o The  possibility  for  development  of  postoperative  hernia  is  rare Disadvantage: o It  gives  a  limited  exposure  and  is  helpful  only  in  case  of  a  sure  diagnosis
100
What  does  thoracolaparotomy  mean?  When  it  is  used?
Creating  a  large  incision  from  the  lower  axilla  to  the  supra-­‐umbilical  area (thoracoabdominal  incision),  opening  the  thoracic  and  abdominal  cavities  and  exposing the  diaphragmatic  region o Used  in  case  of  big  tumors  of  the  liver,  renal  tumors,  possibly  total  gastrectomy, operations  around  the  cardia  region,  esophageal  tumors
101
What  factors  did  contribute  to  the  spreading  of  laparoscopic  operations?  
The  technical  development,  training  operations  and  the  patient’s  increased  demands  for the  minimally  invasive  surgeries  contributed  to  the  wide  spread  
102
What  are  the  disadvantages  of  open  surgery?
Big  exposure,  more  trauma Postoperative  pain  depends  mostly  on  the  size  of  the  surgical  wound It  is  harmful  to  keep  the  body  cavity  open  for  a  long  time  (due  to  vaporization,  drying, etc.) Danger  of  secondary  injuries  during  exposure  (e.g.  intestines,  spleen,  lungs) Increased  possibility  for  later  adhesions The  bigger  the  wound,  the  bigger  is  the  possibility  for  postoperative  complications  (e.g. infections,  hernias)
103
What  are  the  advantages  of   laparoscopic  surgery?  
``` Less  postoperative  discomfort Much  smaller  scars Less  internal  scarring Quicker  recovery  time Shorter  hospital  stays Earlier  return  to  full  activities ```
104
What  does  pneumoperitoneum  mean?  
Insufflating  the  peritoneum  with  gas  to  create  a  workspace  for  the  laparoscopic  surgeon
105
What  kind  of  gas  can  be  used  for  pneumoperitoneum?  
Carbon  dioxide  and  nitrous  oxide  are  the  preferred  gases  nowadays o The  first  gas  used  was  filtered  room  air,  but  this  supports  combustion,  and  so does  N2O  (so  it  is  not  used  for  prolonger  procedures) Helium  can  also  be  used,  but  it  does  not  have  any  advantages  over  CO 2
106
Introduce  the  usage  of  the  Veres  needle!  
The  Veres  needle  is  used  to  create  a  pneumoperitoneum  with  the  closed  access technique It  is  inserted  blindly  through  the  sub-­‐umbilical  area  and  then  used  to  create  the pneumoperitoneum
107
How  and  on  what  level  of  pressure  can  the  pneumoperitoneum  be  used  safely?  
The  best  operating  intra-­abdominal  pressure  is  between  10-­15  mmHg o 15-­20  mmHg  is  optimal,  and  actual  pressures  above  20  mmHg  are  dangerous (compression of IVC etc) The  insufflator  will  maintain  an  optimal  actual  pressure  by  constantly  monitoring  and make  small  changes  in  pressure  to  maintain  the  optimal  pressure
108
What  type  of  telescope  is  popular  in  laparoscopy?
Hopkins  rod  lens  system: o The  advantages  are  greater  light  transmission,  better  image  quality,  wider  field of  view  and  image  magnification o It  utilized  longer  rods  of  glass  and  smaller  air  spaces  between  the  lenses
109
What  do  you  know  about  the  laparoscopic  light  sources?  
Illumination  of  the  abdominal  cavity  is  important  for  orientation Currently  a  150-­‐300  W  fan-­‐cooled  xenon  light  source  is  used  to  provide  color-­‐corrected light  for  extended  period  of  time The  illumination  is  transmitted  to  the  laparoscope  via  a  flexible  fiber-­‐optic  light  guide The  camera  is  connected  to  the  optic,  which  transmits  it  to  the  monitor
110
List  the  difficulties  of  the  laparoscopic  technique!  
* Two-dimensional approach and three- dimensional activity * Eye-hand coordination * Feeling the depth * Coordinated use of the dominant and non-dominant hands * Lack of the tactile sensation * Limited movement * Continuous care of the technical equipment
111
In  which  surgical  fields  do  we  use   microsurgical  techniques?
``` Neurosurgery Traumatology Ophthalmology Maxillo-­‐facial  surgery Plastic  surgery ```
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What  kind  of  special  instruments  are  needed  for  microsurgical  interventions?  
The  iris  forceps Needle  holders Scissors  with  blunt  tips Approximator:  a  hemostat  with  two  tips,  which  can  be  slipped  along  a  single  axis  toward each  other  and  fixed Bipolar  coagulator o The  electricity  passes  only  through  the  tissue  located  between  the  tips  of  the forceps Microsurgical  needles  and  threads  (8/0,  9/0,  10/0  and  11/0)