Oral Surgery Flashcards
Give a definition of a cyst.
A cyst is a pathological cavity having fluid or semi-fluid contents, which has not been created by the accumulation of pus. These occur more only in the jaws than elsewhere are and often more epithelial lined.
What cells do radicular cysts arise from?
Cells of Malassez
What cells form dentigerous cysts?
Remnants for the CEJ in the follicular tissues.
At cellular level, what initiates a cyst to form?
- Epithelial remnants triggers an inflammatory response causing proliferaiton of these cells.
- Ball of growth forms and the central cells within this ball undergoes apoptosis therefore the peripheral cells continue to proliferate.
- This forms a fluid filled sac which slowly grows causing hydrostatic pressure on the bone which then results in osteoclasts being activated resulting in resorption.
Can a cyst erode the overlying cortical bone due to hydrostatic pressure?
Yes
Name some signs and symptoms of cysts.
- Asymptomatic - chance finding of radiographs
- Bony exapansion (egg shell crackling)
- Fluctuant swelling
- Missing teeth
- Carious, discoloured, fractured teeth
- Tilted/displaced teeth
- Discharge sinus
- Loose teeth
- Mental hypoesthesia
- Hollow percussion note
- Pain and swelling if secondarily infected
- Pathological fracture.
What are some investigations you would carry out if suspected a cyst?
- Vitality test
- Radiology
- Aspiration of cyst contents
- Biopsy
What are 3 management aims for cysts?
- To eradicate the pathology
- To minimise surgical damage
- To restore function quickly
Name 6 treatment options of cysts?
- Enucleation - first line
- Marsupialisation
- Enucleation and marsupialisation
- Enucleation and curretage/excision
- En bloc resection jaw- continuity maintained
- partial resection- continuity lost.
What is enucleation?
- This is the complete removal of the cyst lining
- Following enucleation closure can be primarily or secondarily by packing defect
- This maybe contraindicated if the cyst is large, involving a number of vital teeth, in a difficult anatomical site or involving a potentially useful unerupted tooth.
What would you need to consider when planning your flap for enucletion?
- Doesn’t directly rest of the osteotomy site e.g crestal incision, well away from the tissues caused the by the cyst.
Name 2 reasons why you would want to eliminate a dead space after removal of cyst?
- To reduce reactionary haemorrhage
- To reduce post op infection
Name examples of how you could eliminate dead space clinically?
- Drain placement
- Procedure to collapse bony walls e.g make cavity slightly more saucer shape
- Use of biological and other materials to fill the space
- Use layered soft tissue closure e,g suturing muscles
Name some advantages of enucleation
- Complete removal of pathology for histopathology
- Cavity heals without complication
Name some disadvantages of enucleation.
- Infection
- Incomplete removal of lining
- Damages to adjacent teeth or antrum
- Weakening of bone
What is marsupialisation?
This involves creating a window or pouch in the cyst lining, suturing the flap to the remaining lining to allow shrinkage of the lesion which may become self cleansing or be subsequently removed
When would you consider marsupialisation for cysts rather than enucleation?
- When the cyst is very large involving many teeth
- Complex medical history or old/frail patients
- Cyst involves an unerupted tooth
What is the difference in surgical technique between enucleation and marsupialisation?
Marsupialisation you cut flap over the osteotomy site.
Why do you make an acrylic bung in marsupialisation
Not easily self cleansable therefore food and debris can get stuck in wound- acrylic bung acts as a stopper preventing large debris from entering.
What are some advantages of marsupialisation?
- Avoids pathological fracture
- Treatment for medically compromised patients
- Avoids damage to adjacent structures
- Allows potentially useful teeth to erupt
Name some disadvantages of enucleation?
- Orifice closes and cyst reforms
- Repeat visits
- Manual dexterity and compliance
- Complete lining not available for histology
List the most common to least common 5 odontogenic cysts?
- Radicular cyst (60-75%)
- Dentigerous cysts (10-15%)
- Odontogenic keratocyst (5-10%)
- Paradental cyst (3-5%)
- Lateral periodontal cyst/gingival cyst (<1%)
Name the most common non-odontogenic cyst?
- Nasopalatine cyst (5-10%)
What % of radicular cysts remain after the tooth has been xla e.g to form a residual cyst?
20%
What is the treatment for a radicular cyst?
Enucleation of cyst and endodontic surgery.
What is the treatment for a residual cyst?
Marsupialise if cyst is very large then enucleate.
What would you see radiographically in a paradental cyst?
Usually distal to lower 8’s - doughnut shaped which is attached to the CEJ. Treatment would be xla and enucleate.
What are lateral periodontal cyst and gingival cyst associated with in which radicular cysts are not?
Vital teeth
What is the treatment for a dentigerous cyst?
- Enucleation with removal of associated tooth
- marsupialisation if unerupted is potentially functional and can be aligned orthodontically.
What does an odontogenic keratocyst arise from and where is the most common area?
- Remnants from the dental lamina
- Posterior mandible
Why is an odontogenic keratocysts difficult when treating with enucleation?
- Lining is very fragile
- Grows in an antero-posterior direction
- Has finger-like projections
- Have daughter/satellite cysts
What are the treatment options for odontogenic keratocysts?
- Enucleation
- Curettage of cavities with cryotherapy?
- en bloc resection an option previously??
If radiograph showed root resorption of other teeth then what would this suggest?
More likely to be a malignancy rather than a cyst - this would need to be biopsied to confirm.
What is Gorlin-Goltz syndrome?
Genetic autosomal dominant condition
- Mutations of PTCH gene found on chromosome 9.
What is clinical features of Gorlin-Goltz syndrome/multiple basal cell naevoid syndrome?
- Multiple odontogenic keratocysts
- Skeletal abnormalities
- Frontal bossing - supra-orbital ridging
- Wide space between eyes
- Multiple basal cell carcinomas.
What is the treatment for lateral periodontal/gingival cyst?
Enucleation.
Name 2 non-odontogenic cysts.
- Nasopalatine duct cyst
- Nasolabial cyst.
What do non-odontogenic cysts form from?
Epithelium from the embryonic arches
What is the common clinical and radiographic presentation of a nasopalatine cyst?
- salty discharge
- slow painless swelling
- positive vitality on teeth
- heart shaped radiolucency in incisive canal.
What is the treatment for a nasopalatine cyst?
- confirm vitality of teeth
- Enucleation via envelope flat palatally.
What is Staphnes idiopathic bone cyst?
- Development anomaly
- Ectopic salivary tissue in concavity in the medial aspect of the mandible below the IAN
- No active treatment required
What are the 2 types of bone cysts?
- Solitary bone cyst
- Aneurysmal bone cysts
What is the treatment for aneurysmal bone cyst?
- Raise a flap, removal of bone to access cyst, curettage of cyst to send for histopathology
- Often curettage for biopsy triggers healing, therefore usually find this resolves post biopsy.
What would you find in the histology of an aneurysmal bone cysts?
Consists of a mass blood-filled space with scattered giant cells.
What are solitary bone cysts?
- Large radiolucency arching up between roots of teeth
- Tend to resolve spontaneously.
What is an ameloblastoma?
- Odontogenic tumour (most common) - arising from tooth forming structures
- Essentially benign but can be locally aggressive and invasive
- Uni or multilocular, defined or diffuse edged, usually displaces adjacent structures.
- 40-50 years 80% mandible
- Need to biopsy
What would your differential diagnoses be if there was a large radiolucency in the posterior mandible and what would you do?
- Odontogenic keratocyst
- Aneurysmal or solitary bone cyst
- Ameloblastoma??
Need to take biopsy here to confirm diagnosis.
What does the management of an ameloblastoma involve?
En bloc resection
How do you differentiate between at radicular cyst and a periapical granuloma?
Periapical granuloma <6mm
>6mm can then be defined as a cyst.
Give examples of conditions in which you would carry out an excisional biopsy to send for histopathology.
- Mucocoele
- Denture induced hyperplasia
- Epulis e.g pyogenic granuloma
- Fibroepithelial poylp
What is mapping biopsys?
Multiple biopsies in different areas
When carrying out an incisional biopsy what part of a white lesion would you want to biopsy?
The worst looking part.
What are some problems that can occur when taking a biopsy?
- inappropriate specimen
- specimen too small or macerated
- cant orientate specimen
- tissues distorted by diathermy or LA
- Lab not informed of need for frozen section
- Lack of clinical detail on form
- Specimen gone up aspirator
When are frozen sections used and what is the disadvantges of this?
- mostly used in hospital setting for intra-operative to determine if got clear margins for cancer
- can be used to diagnose immunobullous disorders
- disadvantage is cannot be used to determine degree of dysplasia.
What is exfoliative cytology?
- removal of surface cells by scraping with a spatula or cytobrush
- widely used in cervical cancer screening
- research continues in its application in diagnosis in oral carcinoma.
What is fine needle aspiration FNAC?
- Determines whether lesion is solid or cystic/fluid filled
- simple to perform - just insert needle into area/swelling
- interpretation difficult but experienced cytopathologist have high success rate
- cyst contents can undergo further test e.g microbiology or protein electrophoresis
- Very useful with lumps in the parotid glands and neck lumps to determine whether the lump is a tumour
What kind of biopsy would you carry out to diagnose with Sjogrens syndrome?
Labial gland biopsys.
What is toluidine blue?
A dye that binds to abnormal tissues to help aid in biopsys. Not frequently used as requires high sensitivity/specificity.
If a lesions is >2cm has a greater potential of being a malignant lesion. True or false?
True.
Where are the 2 places in the mouth where you dont have salivary glands.
- Gingivae
- Hard palate
When do the major saliva glands only produce saliva.
When you eat. The rest of the time when fasting they do not produce saliva which can sometimes cause bacteria from the mouth to enter the duct and cause an infection.
Where anatomically is the parotid gland, what is the parotid duct called and what type of saliva does it produce?
Parotid gland is located anterior to the ear, behind the ramus of the mandible
- Stensons duct which opens opposite the second maxillary molar tooth.
- Produces predominantly serrous saliva.
What are the different parts/lobes of the parotid gland?
- superficial parotid sits above the facial nerve accounts for 4/5 of the parotid
- deep lobe sits below the facial nerve
- Tail of the parotid sits behind the angle of the mandible
- Accessory lobe individual gland that sits above the gland.
What important structures run through the parotid gland?
- Facial nerve
- Terminal branches of external carotid artery
- superficial temporal artery
- Maxillary artery
- Greater auricular nerve?
Where is the submandibular gland located anatomically, what is the duct called and what type of saliva does it produce?
- paired glands located in the submandibular triangles. Encapsulated and covered by cervical fascia and stylohyoid ligament.
- Whartons duct drains into the floor of the mouth
- Mixed seromucous glands.
Where is the sublingual gland located anatomically, what is the duct called and what type of saliva does it produce?
- smallest, lies on the floor of mouth covered only by oral mucosa.
- Drains via tiny ducts (Rivinis duct) on the plica sublingualaris or a common duct which joins the submandibular duct (Bartholins duct)
- Mucous gland