Oral Receptors Flashcards

1
Q

Why is it important to know about receptors in dentistry?

A

1) Malocclusion:
- CNS will detect + correct
- both upper and lower jaw
2) Bruxism:
- awareness of where jaw is
- drugs, iatrogenic
3) Orthodontics:
- chewing pattern must be re- programmed
You have to move teeth and do things so slowly, not only because you may destroy structure but your brain needs time to reprocess that.

4) TMJ disorders:
- trigeminal (sensory V3)
5) Pain!
- oral cavity a common site for pain

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2
Q

What are exteroreceptors, proprioceptors, and interoceptors?

A

Classified depending on their physical location throughout the body

Exteroceptors - just beneath the skin
Proprioceptors - within muscles and joints
Interoceptors - within the viscera

Exteroceptors - 1° for pain, touch temperature and pressure (nociceptor, mechanoreceptor, thermoreceptor)

Proprioceptors - position & movement, vibration and pressure, pain

Interoceptors - pressure (distention), pain

All of them can transmit pain.
Fastest neurotransmition for proprioceptors, NOT FASTEST FOR PAIN

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3
Q

How are receptors differentiated?

A

Receptors are differentiated on the basis of whether they are encapsulated or not

Encapsulated

Meissner's (mechanoreceptors)
Pacinian (mechanoreceptors)
Ruffini's (mechanoreceptors)
Golgi Tendon (proprioceptors)
Muscle spindle (proprioceptors)

Non-encapsulated

Merkel’s Disks (mechanoreceptors)
Free nerve endings

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4
Q

How are peripheral nerves classified?

A
Characteristics of peripheral nerves:
They are classified according to different criteria:
	size
	conduction velocity
	whether possess a myelin covering

Basic Rule
Fibres that are required to transmit important information do so at much faster rates
Applies to both sensory and motor nerves

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5
Q

What are the motor and sensory neurons?

A

Only sensory nerves get numeric names (e.g. type 2 affterent)
If you’re using alphabetic it can be either motor or sensory.
Group 1 is faster because it has more myelin.
C type fibers have no myelin so they’re the slowest.
Most autonomic fibers are B type fibers, they are all motor (they aren’t on this chart!!!!!)

ABC motor and sensory. 
A alpha (Group I) is proprioceptors of skeletal muscle. 

Abeta (group II) is mechanoreceptors of skin.

Adelta (Group III) is pain, temperature

C (group IV) are temperature, pain, and itch. Unmyelinated and therefore the slowest.

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6
Q

So once again Sensory fibres from the soma (Somatic afferents) have been classified according to where the information comes from (basically this is a physiological distinction), so what do types I - IV deliver?

A

Type I - muscle spindle / Golgi tendon endings
Type II - m. spindle / touch / pressure receptors
Type III - myelinated pain / temperature receptors
Type IV - unmyelinated pain / temp. receptors

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7
Q

What are the fastest transmitting fibers?

A

Muscle spindle and golgi tendon organ are the fastest transmitting.

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8
Q

What is the motor system and what is it divided into?

A

There is also a system that conveys motor information
This motor division is subdivided into
somatic efferent (muscles) and
visceral efferents (controlling glands, smooth muscle)
What is an example of a visceral efferent motor nucleus that is important for dentistry?
Inf. / Sup. Salivatory Nucl.

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9
Q

What is the most complicated/complex receptor and why?

A

The most complicated / complex receptor is the muscle spindle
This is because it has both a sensory component and a motor component
All other receptors have only the sensory component

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10
Q

What do neuromuscular spindles provide sensory data for?

A

Provide sensory data for

  • reflex adjustments of muscle tonus
  • contribution of cerebellum to motor function
  • sensory / motor integration at cortical level
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11
Q

What is the organization of a muscle spindle?

A

Organization:(Fig 5 -1)

  • C.Tissue capsule surrounding a group (2 - 10) of specialized muscle fibres (intrafusal fibres)
  • Spindles exist in the body of the muscle itself amongst the extrafusal fibres (in parallel)
  • Each spindle is expanded at its central region into a fluid filled bag
  • have both motor input and sensory output
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12
Q

What are the two types of intrafusal fibers?

A

Nuclear - bag

Nuclear – bag
Thicker
3 - 4 nuclei clustered in the bag region
more centrally located within spindle

Nuclear - chain

Nuclear – chain
Thin
Nuclei distributed down the equatorial plane of each cell
more peripherally located in spindle

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13
Q

What is an intrafusal fiber?

A

But What is an Intrafusal fibre?
It is a specialized muscle / receptor cell, shaped like a spindle that has contractile regions on either end and a relatively more central region that is contacted by sensory nerve fibres and is non-contractile

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14
Q

What are the two different types of sensory nerve endings associated with the intrafusal fibers?

A

primary endings (annulospinal); and
secondary endings (flowerspray)
Report the length of muscle spindle back to the CNS
- under resting conditions, these sensory axons send ongoing information to the CNS that is mostly unconscious
these axons increase their firing rate when the muscle spindle is stretched )

Difference between the two endings is that the annulospinal are faster than the flowerspray.

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15
Q

What are primary endings in neuromuscular spindles?

A

Primary endings
Also called annulospiral endings

Classified as Type Ia afferent endings - very rapid conduction velocities

Associated with the central portions of both the nuclear - bag and nuclear - chain fibres
Annulospiral Endings - Ia afferents - Very rapid conduction velocities of sensory information – more centrally located and innervates both bag and chain

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16
Q

What are secondary endings in neuromuscular spindles?

A

Secondary endings
Also called flowerspray endings

Classified as Type II afferent endings - fast conduction velocities

Associated mainly with the peripheral portions of the nuclear - chain fibres
Flower Spray Endings – Type II afferents - Rapid conduction velocities of sensory information-
Peripheral and primarily associated with chain

17
Q

Associated with the intrafusal fibres there are also different types of motor nerve endings
called?

A

Gamma motor fibers (may be up to 4 different types)

18
Q

What are group Agamma efferent fibers (of gamma motor fibers)?

A

Gamma motor fibres- Group Agamma efferent fibres
- rapid conduction velocities
- maintain tone in muscle
Subdivided into
dynamic gamma and beta: enhance sensitivity of Ia fibres to respond to activities that require rapid changes in muscle length
static gamma and beta: posture, slow movements

19
Q

What is the summary of extrafusal and intrafusal muscle fibers?

A

Extrafusal muscle fibres  Aα motor efferent = innervates the muscle
Intrafusal muscles fibres  sensory and motor
Sensory: 1 = Group Ia = annulospiral
2 = Group II = flowerspray
Motor: Group Aγ motor fibres: fusimotor
- dynamic vs. static

20
Q

What are the very sensitive receptors located within the tendon of muscle?

A

These are also very sensitive receptors

  • located within the tendon of muscle
  • encapsulated receptor
  • spindle shaped
  • comprised of many collagen fibres
21
Q

How are these golgi tendon organs arranged?

A

Anatomical arrangement of up to 50 GTO’s at the junction between a muscle and its joining tendon

Differences (cf neuromuscular spindle)
- organized in series with a muscle, location
- no contractile element in the receptor
- innervated by a single large-diameter sensory (afferent) nerve - Type Ib
(still very fast conduction)

22
Q

What do golgi tendon organs do?

A

GTO in tendon (to muscle border)

Ib sensory fibres weave btwn the collagen fibres of the GTO

  • pull on capsule = tension created btwn tendon and muscle fibre b/c axons squeezed = axons activated, myelinated as leaves GTO)

Tension or looseness is detected by the axons.

Basic Action -
When skeletal muscle fibres (extrafusal) contract, they shorten and cause a tension increase in the collagen bundles
This leads to a compression of the unmyelinated nerve which ramifies throughout the encapsulated ending

23
Q

What does the amount of firing of the golgi tendon organ depend on?

A

Basic Action -
The size of the generator potential and the frequency of action potential discharge is proportional to the rate and magnitude of the applied force
(Fig 5 - 7)
The amount of force required to generate a response varies due to stiffness/elasticity of the connective tissue capsule of the GTO

As you get older and the collagen gets stiff, you can activate it easily.

24
Q

Are golgi tendon organs referred to as an “on/off switch”?

A

More stretch force = more AP’s for a longer time and a greater difference in voltage