Oral Pathology - Logan Flashcards
What are the 8 different bacterial infections?
Syphilis, tuberculosis, gonorrhoea, leprosy, ANUG, cancrum oris, actinomyces, osteomyelitis
What are the viral infectious diseases?
Herpes simplex virus, zaricella-zoster virus, human herpes virus 8, epstein barr virus, cytomegalovirus, coxsackie virus, human papilloma virus
What are the 4 types of human papilloma virus?
Squamous papilloma, condyloma accuminatum, focal epithelial hyperplasia, oropharyngeal carcinoma
What are the developmental lesions (epithelial) in the oral cavity?
Leukoedema, white sponge nevus
What are the developmental lesions (CT) in the oral cavity?
Gingival fibromatosis, haemangioma, lymphangioma
What are the developmental lesions (ectopic) in the oral cavity?
Fordyce spots, lingual thyroid tissue, lingual tonsils
What are the developmental lesions (miscellaneous) in the oral cavity?
Benign migratory glossitis, melanotic macule, melanocytic nevus, amalgam tattoo
What are the epithelial hyperplastic lesions in the oral cavity?
Linear alba, cheek biting, smoker’s keratosis, chronic hyperplastic candidiasis, oral HPV
What are the hyperplastic lesions (CT) in the oral cavity?
Denture associated (fibroblastic epithelium, papillary hyperplasia of the palate), localised soft tissue lesions (fibroepithelial polyp, condyloma accuminatum, peripheral giant cell granuloma, calcifying fibroblastic granuloma), generalised gingival enlargement
What are the hyperplastic (mucosal) lesions in the oral cavity?
Giant cell fibroma, benign lymphoid hyperplasia, traumatic neuroma, verruciform xanthoma
What is the TNM staging?
T1: <2cm
T2: 2-4cm
T3: >4cm
T4: >4cm and invasion into local tissue
N0: no LN involvement
N1: ipsilateral involvement of LN
N2: contralateral/bilateral involvement
N3: fixed palpable nodes
M0: no metastases
M1: metastases present
Stage 1: T1N0M0
Stage 2: T2N0M0
Stage 3: T3N0M0, any T with N1
Stage 4: any T, any N, M1; any T with N2/3
How do you differentiate leukoedema from white sponge nevus histologically?
Thickened parakeratin layer, no dysplasia
Which lesion is associated with large stellate and multi-nucleated giant fibroblast?
Giant cell fibroma
Which diseases are associated with chronic inflammatory cell infiltrate?
Gingival fibromatosis (mild), chronic hyperplastic candidiasis, papillary hyperplasia of the palate
Which condition has good prognosis but leave severe facial deformities?
Cancrum oris
What are the 7 differential diagnosis for lichen planus?
Lichenoid drug reactions, lupus erythematosus, candidiasis, Cheek biting, GvHD, idiopathic leukoplakia, SCC
What are the differential diagnosis for fibroepithelial hyperplasia?
Clinical: neoplasm, haemangioma, peripheral giant cell granuloma, calcifying fibroblastic granuloma
Histological: granulation tissue, haemangioma
What are the differential diagnosis for leukoedema?
White sponge nevus, smoker’s keratosis, frictional keratosis
What are the differential diagnosis for primary and secondary herpes?
Primary: ANUG, pharyngitis, erythema multiforme
Secondary: aphthous ulcer, developmental lesions, vesiculobullous diseases
Differential diagnosis for squamous papilloma?
Verruciform xanthoma, papillary hyperplasia, condyloma accuminatum
