oral path Flashcards
Ludwig’s angina is infection of __________ space
submandibular
swollen hyperplastic fungiform papillae
+ strawberry tongue
scarlet fever
valveless facial veins
cavernous sinus thrombosis
external ear changes
Treacher Collins
ectopic sebaceous glands that are yellow papules/plaques
fordyce granules
results from local trauma or infection with developing tooth bud
Turner tooth
which type of aphthous ulcer is NOT preceded by a vesicle?
recurrent type
tx: corticosteroid
characterized by subepithelial separation at basement membrane zone ** subepithelial split
Benign mucous membrane Pemphigoid
autoimmune - antibody rxn at epi-CT interface
white “wipeable” patch with red underlying base
pseudomembranous candidiasis
atrophy of filiform papillae, red, midline of tongue at jxn of posterior third and anterior 2/3
median rhomboid glossitis
tx: antifungal nystatin or clotrimazole
wandering transected nerve with scar tissue
traumatic neuroma
painful
local reactive growth, usually on gingiva (interdental papillae), exophytic, bleeds easily, non painful, proliferative, grows fast
pyogenic granuloma
liver colored, MULTINUCLEATED GIANT CELLS, limited to alveolar ridge/gingiva, anterior to 1M
Peripheral giant cell granuloma
intrabony, MULTINUCLEATED GIANT CELLS, anterior to 1M, bone destruction 2* to chronic renal disease
central giant cell granuloma
epithelium, white or pink-white, rough cauliflower surface, elevated lesion , more frequent than some “oma”s ,
squamous papilloma
most common connective tissue tumor
fibroma
reactive, not a true tumor, hyperplasia (not neoplasia), firm smooth pink, common on tongue
fibroma
nodule with smooth papillate surface, granular cells in cytoplasm, often histo has PSEUDOEPITHELIOMATOUS HYPERPLASIA (resembles SCC)
granular cell tumor
1 site of granular cell tumor
dorsum of tongue
white patch that doesn’t wipe off, cytology doesn’t help, must biopsy, if 2+ areas then incisional biopsy
leukoplakia
red plaque that doesn’t wipe off, highly likely to undergo malignant transformation and severe dysplasia
erythroplakia
tx: incisional biopsy
intraoral site with highest risk of SCC
floor of mouth
most common intraoral site of SCC
mid lateral border of tongue
least likely site of SCC
hard palate
most common SCC in general
lower lip
can be preceded by actinic cheilitis
most common node with metastasis in SCC
submental node
SCC on radiograph shows as
poorly defined radiolucencies without reactive sclerotic border
common in posterior mandible, poorly defined radiolucency without sclerotic border, does NOT cause shift in occlusion
metastatic disease of jaw
benign neoplasm of salivary gland that is most common on UPPER lip, women, asymptomatic, can be multinodular
monomorphic or canalicular adenoma
stretches and disappears when you pull, intracellular edema of cells, often BILATERAL on buccal mucosa, no treatment necessary
leukoedema
seen with smokeless tobacco habit**, not likely to metastasize, buccal vestibule common (different from SCC), large elevated papillary lesion
verrucous carcinoma
p53 tumor suppressor gene
most common associated in field cancerization
most common salivary gland tumor
pleiomorphic adenoma
most common malignant salivary gland tumor and it is mainly where?
mucoepidermoid carcinoma
mainly in parotid
melanosis may be seen in ___________ insufficiency
adrenal
a TRUE CYST (epithelial lining), well circumscribed RL between roots of erupted, vital teeth - often mand premolars
lateral periodontal cyst
tumor common in posterior mandible but CAN CROSS MIDLINE, most common true odontogenic tumor (#1 odontogenic cyst), MULTILOCULAR RADIOLUCENCY, often associated w. impacted tooth
ameloblastoma
tx remove jaw
histology of ameloblastoma
reverse polarization of nuclei of columnar cells in periphery
has neoplastic epithelial AND mesenchymal tissue so true mixed tumor, younger patients, slight pain/swelling, not aggressive, pure lucency
ameloblastic fibroma
odontoma portion is radiopaque, rest is lucent, slight pain/swelling, not aggressive, posterior jaws, young
ameloblastic fibroodontoma
young people, radiopacity with lucent rim( (follicle), can be compound with identifiable toothlets or complex with unidentifiable mass
odontoma
young, unerupted tooth, treatment is ENUCLEATION, radiograph snowflake calcifications in RL surrounding crown and impacted root
AOT
Adenomatoid odontogenic tumor
lack enamel, normal cementum/dentin, normal root/crown shape, pulp chambers and root canals normal
amelogenesis imperfecta
dentinogenesis imperfecta
bulbous bell shaped crowns, obliterated pulp chambers, constricted CEJ, opalescent blue/gray dentin,
multilocular bilateral radiolucencies, jaw expansion that stops after childhood
cherubism
UNILATERAL mn or mx expansion, painless swelling, onset before puberty, C/C is “my teeth don’t fit”, non infectious process
CAFE AU LAIT spots
GROUND GLASS radiographic
fibrous dysplasia
tx bone shaving after 20 when stable
cafe au lait spots in polyostotic form
mccune albright syndrome
associated with pulpitis, nonvital, periapical RADIOPACITY, does not connect with root - root outline always visible unlike cementoblastoma
condensing osteitis
no pulpitis, no pain, no expansion, radiopacity without lucent rim, not connected to root
idiopathic osteosclerosis
tx none
radiolucency with SCALLOPED MARGINS, PSEUDOCYST, spontaneous healing after exploratory surgery
traumatic bone cyst
bilateral maxilla, older people, high malignant trans.
COTTON WOOL appearance
REVERSAL lines with MOSAIC appearance
cranial nerve deficits as nerve compressed
ALKALINE PHOSPHATASE INCREASED
Paget’s disease
tooth floating in air on radiograph, made of Langerhans cells
Langerhans cell disease
Ominous sign of malignancy bone involvement
spontaneous paresthesia of lower lip
Sign of benign bone involvement
cortex remains intact, thinned, or expanded
calcification of falx cerebri, bifid rib, basal cell carcinoma, cysts of jaws
nevoid basal cell carcinoma syndrome
hyperdontia, intestinal polyps (FAP > colon ca)
Gardner syndrome
CN 7 paralysis, lasts about a month
Bell’s palsy
BULLS EYE / TARGET LESIONS on hands and feet, crusted bleeding vesicles on vermilion and intraoral sites EXCLUDING GINGIVA, young males
erythema multiform
involves eye, mouth, genitalia > very bad. erythema multiform major
Stevens Johnson Syndrome
vesiculoulcerative, intraepithelial (supraepithelial) cementing substance
POSITIVE NIKOLSKY SIGN
INTRAEPITHELIAL SPLIT, BASAL LAYER INTACT
pemphigus vulgaris
tx: corticosteroids
autoimmune, replace normal CT with dense collagen > fibrosis, loss of mobility, altered organ fxn
PDL WIDENING, TRISMUS, mask like induration
Scleroderma (progressive systemic sclerosis)
DESQUAMATIVE FILIFORM PAPILLAE, sore or burning, tx with corticosteroid rinse, moves around, dorsum tongue most common
benign migratory glossitis (geographic tongue)
tx corticosteroid rinse
DESQUAMATIVE FILIFORM PAPILLAE, sore or burning, tx with corticosteroid rinse, moves around, dorsum tongue most common
benign migratory glossitis (geographic tongue)
tx corticosteroid rinse
white coagulative necrosis of surface, RUBS OFF with difficulty
aspirin burn
does not occur intraorally, painless ulcer on SUN EXPOSED, raised margins, ASSOC TELANGIECTASIA
most common form of skin cancer
basal cell carcinoma
floor of mouth swelling, FROG’S BELLY, bluish, recurrence, true retention cyst , INCREASE IN SIZE BEFORE MEAL, histiocytes visible
ranula
slight RADIOPAQUE dome shaped from floor of sinus, asymptomatic
antral pseudocyst
result of proliferation of remnants of reduced enamel epithelium, common site 3M and posterior mandible, pericoronal RL at CEJ of unerupted tooth
dentigerous cyst
calcified or elongated stylohyoid ligament; neck pain with chewing, yawning, opening mouth
Eagle Syndrome
crop of painful vesicle ulcers, markedly UNILATERAL
herpes zoster
slightly compressible, DOUGHY, midline distribution usually anterior FOM
dermoid cyst
multiple mucosal neuromas
medullary thyroid carcinoma
adrenal pheochromocytoma
multiple endocrine neoplasia syndrome
most common non-odontogenic developmental cyst, teeth vital, true cyst (epi lining), heart shaped RL
incisive canal cyst
a GENODERMATOSIS (autosomal dominant), BILATERAL mucosa, thick, white folds of tissue , no eye involvement
white sponge nevus
defect in normal keratinization
PREMALIGNANT, vermilion border becomes indistinct, sun exposure
actinic cheilitis
seen in HIV, caused by EBV, white rough plaque on lateral border of tongue
oral hairy leukoplakia
middle aged black women, mandibular anterior teeth, TEETH ARE VITAL!, asymptomatic, no expansion or pain
multifocal RLs that become mixed RL/RO and finally RO
periapical cemento-osseous dysplasia
multiquadrant, fibro-osseous intrabony lesion, complication is 2* osteomyelitis, RL and RO
florid osseous dysplasia
Wickham’s striae, comes in reticular, erosive, and hyperplastic types, negative Nikolskys sign
Lichen planus