oral mucosal disease Flashcards
When should a mucosal lesion be referred to oral medicine?
Anything the dentist thinks might be cancer or dysplasia
Any symptomatic lesion that has not responded to standard treatment
Any benign lesion that the patient can’t be persuaded is not cancer
What are the strata layers of the epithelium?
Stratum corneum - most superficial
Stratum granulosum
Stratum spinosum
Stratum basale
Where does cell division occur in the strata?
Suprabasal cells only
What is acanthosis?
Hyperplasia of the stratum spinosum
What are elongated rete ridges?
Hyperplasia of basal cells
What is atrophy?
Reduction in viable layers
What is erosion?
Partial thickness loss of epithelium
What is ulceration?
Complete loss of epithelium with fibrin on the surface
What is oedema and what are the 2 types?
Swelling
Intracellular - each cell is slightly bigger
Intercellular (spongiosis) - fluid between epithelial cells
What is a blister?
Collection of fluid within or just below the epithelium
Called vesicle or bulla depending on size
How does the mucosa change with age?
Progressive mucosal atrophy
How does the mucosa change with nutritional deficiency?
Iron or B vitamins - predisposes to infection
Give 3 examples of benign mucosal conditions
Geographic tongue
Black hairy tongue
Fissured tongue
What is geographic tongue and what is the prevalence?
Alteration in maturation and replacement of normal epithelial surface
Affects 1-2% of population, less in children
What are the symptoms of geographic tongue?
Sensitive with acidic/spicy foods - intermittent
Much worse in young children
Most patients have no symptoms