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Oral Histo-Final > Oral Mucosa 2 > Flashcards

Oral Mucosa 2 Flashcards

1
Q

What branchial arch does the mucosa of the body of the tongue derive from?

A

BA 1

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2
Q

T/F: Tongue root mucosa is derived from BA 2

A

False- This mucosa is from BA 3

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3
Q

What lies beneath the lamina propria of the tongue?

A

Muscle. There is no submucosa present.

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4
Q

What cranial nerves convey taste?

A

CN VII, IX, X

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5
Q

Which CN provides somatosensory innervation to the anterior mouth?

A

CN V

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6
Q

Which CN provides somatosensory innervation to the posterior tongue/pharynx?

A

CN IX

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7
Q

What do A-beta fibers convey?

A

Touch

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8
Q

Pain is conveyed through A-delta and C fibers. T or F?

A

True

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9
Q

Which fiber responds to both painful and innocuous cooling?

A

C fiber

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10
Q

Which fiber responds to both painful and innocuous warmth?

A

A-delta fiber

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11
Q

What mechanoreceptor terminates b/t rete pegs (never enters the epithelium), and senses dynamic, rapidly adapting forces?

A

Meissner’s Corpuscles

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12
Q

Where do Merkel receptors terminate?

A

At the apices of rete pegs

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13
Q

What type of force do Merkel receptors detect?

A

Static forces

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14
Q

T/F: Free nerve endings always terminate in the lamina propria.

A

False- They can either terminate in the lamina propria or the epithelium

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15
Q

Do Merkel and Meisner receptors code for pain if the stimulus reaches noxious levels?

A

No, only mechanoreception. Free nerve endings carried by A-delta and C fibers deal with pain.

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16
Q

What are the 5 types of taste and an example of each?

A 
Sweet-Sugars
Umami-Amino Acids
Salty-Sodium
Sour-Acids
Bitter-Coffee, Beer, (Notes say alkaloid, purine base, glycosides)
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17
Q

How is a taste bud oriented in regards to the basal lamina?

A

Right angle

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18
Q

What is the shape of a taste bud?

A

Goblet-shaped

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19
Q

T/F: All cells of the taste bud possess microvilli.

A

False-Only the Elongated cells possess them. (I looked up if all 3 types of elongated cells have microvilli and came to the conclusion that only Type I and II have them.–Google Books, “Taste and Smell: An Update”)

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20
Q

About how many taste buds are on the oral mucosa?

A

8,000

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21
Q

What are the percentages for taste buds for tongue, pharynx/larynx, and soft palate?

A

Tongue-68%
Pharynx/Larynx-27%
Soft Palate-5%

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22
Q

T/F: Circumvallate Papillae are located on the posterior 1/3 of tongue

A

False: They are located on the most posterior portion of the anterior 2/3 of the tongue

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23
Q

Where are fungiform papillae located?

A

Anterior 2/3 of dorsum of tongue

24
Q

Location of foliate papillae?

A

Lateral portion of tongue at most posterior portion of the anterior 2/3.

25
Q

What papillae does the chorda tympani branch of CN VII (BA 2) innervate?

A

Fungiform Papillae

26
Q

Taste buds are located on what surface of fungiform papillae?

A

Dorsal

27
Q

About how many taste buds are on 1 fungiform papillae?

A

average of 3

28
Q

On average, how many taste buds do filiform papillae contain?

A

0-no buds here

29
Q

What type of fibers innervate filiform papillae?

A

Only Somatosensory-Merkel&Meisners (A-beta), free nerve endings (C, A-delta)

30
Q

What CN innervates foliate papillae?

A

CN IX (BA 3)

31
Q

What is location of taste buds on foliate papillae?

A

In trenches on sides, not on top like the fungiform papillae

32
Q

Which papillae are most closely associated with Von Ebner’s glands?

A

Foliate and Circumvallate

33
Q

Where are circumvallate taste buds located?

A

In trenches on sides

34
Q

What is the location of taste buds that mainly respond to deviations from isotonicity?

A

Larynx

35
Q

What was main point of study regarding responses of individual fungiform papillae and taste?

A

Pretty much 1 fungiform can discriminate b/t multiple tastes.

36
Q

Are taste stimuli undetectible on the front side of the tongue contralateral or ipsilateral to chorda tympani anesthesia?

A

Ipsilateral

37
Q

Does chorda tympani nerve anesthesia effect “whole mouth” taste perception?

A

Very minimally b/c of the functional redundancy of the taste system makes it resilient to partial taste loss

38
Q

According to study: Do all individuals have about the same number of fungiform papillae?

A

No, the number varies greatly person to person

39
Q

Do all people have the same ability to taste different molecules? What about PTC?

A

Everyone has a different affinity to taste specific molecules. The ability to taste PTC is an inherited trait.

40
Q

Name a specific bitter receptor.

A

Tas2r

41
Q

What did she “impress” upon us in regards to the vegetable bitterness and intake studies?

A

Certain vegetables taste more bitter to those who are homozygous for the PTC-senstive form of tas2r38 and vice versa. This varying sensitivity has been shown to impact the intake of certain vegetables based upon bitterness

42
Q

Where are perigemmal cells located on the taste bud?

A

Lateral aspect

43
Q

What is the main function of basal cells of taste bud?

A

Renewal-very high turnover

44
Q

Are type I elongated cells dark or light in EM views?

A

Dark

45
Q

Which type of elongated cell has a suggested supportive role?

A

Type 1 Dark-stains for glial markers, supportive role.

46
Q

T/F: Type 1 Dark cells have microvilli and synapse with a primary afferent nerve

A

False-They do have microvilli but do not synapse

47
Q

Which elongated cells express receptors for taste and respond to taste stimuli?

A

Type II and Type III Light

48
Q

Which taste(s) corresponds to Type II Light cells?

A

Bitter, Sweet, Umami

49
Q

Which taste(s) corresponds to Type III Light cells?

A

Sour

50
Q

T/F: Type III Light cells synapse with primary afferent nerve

A

True. Type II Light do NOT synapse with primary afferent

51
Q

What is used as a non-synaptic taste transmitter for Type II cells? (Also Type III can do this as well)?

A

ATP

52
Q

What intermediate filament protein is thought to reflect rapid turnover of taste receptor cells?

A

Keratin-19 (K19)

53
Q

What appears at week 12 embryologically?

A

Taste Pores

54
Q

When does the tongue appear?

A

Week 4

55
Q

When do taste buds 1st appear?

A

Week 8

56
Q

What happens in EW 8?

A

Lingual papillae develop, taste buds 1st appear

57
Q

Glance at Enfamil/Nutramigen study, no questions posted.

A

Good luck

Oral Histo-Final (3 decks)

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