oral medicine Flashcards
What are possible oro-facial soft tissue infections
Viral
-Primary herpes
-Herpangina
-Hand foot and mouth
Bacterial
-Staphylococcal
-Streptococcal
-Syphilis
-TB
-Cat Scratch Disease
Fungal
-Candida
What is Primary hepatic gingivostomatitis
Its an acute Infectious disease caused by herpes Simplex Virus I
Primary infection common in children
Transmission by droplet formation with 7 day incubation period
Almost 100% of the adult population are carriers
lasts 14 days
What are S&S of Primary Herpetic Gingivostomatitis
Fluid filled vesicles
–rupture to painful ragged ulcers on the gingivae, tongue, lips, buccal and palatal mucosa
Severe oedematous marginal gingivitis
Fever
Headache
Malaise
Cervical lymphadenopathy
What is the treatment of PHG
Bed rest
Soft diet/hydration
Paracetamol
Antimicrobial gel or mouthwash
topical acyclovir cream for immunocompromised children
What is the most common complication with PHG
Dehydration
What is the recurrency of PHG
Recurrent disease in 50-75% = herpes labialis (cold sores)
As it remains dormant
Coxsackie virus can cause what 2 herpatic like infection
Herpangina
-Vesicles in the tonsillar/ pharyngeal region
-Lasts 7-10 days
Hand/ foot and mouth
-Ulceration on the gingivae/tongue/cheeks and palate
-Maculopapular rash on the hands and feet
-Lasts 7-10 days
What is oral ulceration
A localized defect in the surface oral mucosa where the covering epithelium is destroyed leaving an inflamed area of exposed connective tissue
What are the 10 key facts in oral ulceration history
-Onset
-Frequency
-Number
-Site
-Size
-Duration
-Exacerbating dietary factors
-Lesions in other areas
-Associated medical problems
-Treatment so far (helpful/unhelpful)
What are the causes of oral ulceration
Infection:
-Viral: Hand foot and mouth/ Coxsackie Virus/ Herpes Simplex/ Herpes Zoster, CMV, EBV, HIV
-Bacterial: TB, syphilis
Immune mediated Disorders:
-Crohns, behcets, SLE, Coeliac, Periodic fever syndromes
Vesiculobullous disorders:
-Bullous or mucous membrane pemphigoid, pemphigus vulgaris, linear IgA disease, erythema multiforme
Inherited or acquired immunodeficiency disorders
Neoplastic/Haematological:
Anaemia/Leukaemia/agranulocytosis/cyclic neutropenia
Trauma
Vitamin deficiencies – Iron, B12, Folate
Recurrent Apthous Stomatitis
What is the most common form of oral ulceration in children
Recurrent Apthous ulceration (RAU)
What do RAU’s look like and what are the 3 patterns
are round or ovoid in shape with a grey or yellow base and have a varying degree of perilesional erythema
3 patterns:
Minor - <10mm
Major - >10mm
Herpetiform – 1-2mm
What are posible aeitiology factors of recurrent ulceration
-Hereditary predisposition (FH in 45%)
-Haematological and deficiency disorders (iron Def in 20%)
-Gastrointestinal disease (Coeliac in 2-4%)
-Minor trauma in a susceptible individual
-Stress
-Allergic disorders
-Hormonal disturbance: Menstruation
When investigating ulceration what do you do
Initial Investigations:
-Diet diary
-Full Blood Count
-Haematinics (Folate/B12/Ferritin)
-Coeliac Screen: Anti-transglutaminase antibodies
What is the management of ulceration
Diet anaylsis may suggest exacerbating food groups
Low Ferritin = 3 months of iron supplementation
Low Folate/B12 or positive Anti-transglutaminase antibodies = referral to paediatrician for further investigation
Manage exacerbating factors:
-Nutritional deficiencies
-Traumatic factors
-Avoid sharp or spicy food
Manage pharmacologically:
-Prevention of Superinfection:
Corsodyl 0.2% Mouthwash
-Protect healing ulcers
Gengigel topical gel (hyaluronate)
Gelclair mouthwash (hyaluronate)
-Symptomatic relief
Difflam (0.15% benzydamine hydrochloride)
Local anaesthetic Spray