Oral Medications Flashcards
Biguanide
Glucophage (Metformin)
Secretagogoues
Sulfonylurea (2nd gen)
Sulfonylurea
Glucotrol (Glipizide)
Amaryl (Glimepiride)
Glynase (Glyburide)
Secretagogoues (short-acting) Meglitinides
Prandin (Repaglinide)
Starlix (Nateglinide)
Thiazolidinediones (TZDs)
Avandia (Rosiglitazone)
Actos (Pioglitazone)
Alpha-Glucosidase Inhibitors
Precose (Acarbose)
Glyset (Miglitol)
DPP-4 Inhibitors
Januvia (Sitagliptin)
Onglyza (Saxagliptin)
Tradjenta (Linagliptin)
Nesina (Alogliptin)
SGLT2 Inhibitors
Invokana (Canagliflozin)
Jardiance (Empagliflozin)
Farxiga (Dapagliflozin)
Steglatro (Ertugliflozin)
Antiadiabtic, Dopamine Agonist
Cycloset (Bromocriptine)
GLP-1 (Glucagon-Like Peptide 1) Receptor Agonists
Byetta (Exenatide) Bydureon (Exenatide ER) Victoza (Liraglutide) Trulicity (Dulaglutide) Adlyxin (Lixisenatide) Ozempic (Semaglutide)
GLP1 RA + Basal Insulin
Soliquia (Lixisenatide + Insulin Glargine)
Xultophy (Liraglutide + Insulin Degludec)
Amylin Mimetics
Symlin (Pramlintide)
Rapid Acting Insulins
Humalog/Admelog (Lispro)
Novolog/Fiasp (Aspart)
Apidra (Glulisine)
Afrezza (Inhalation)
Short Acting - Regular Insulin
Novolin R/Humulin R (Regular Insulin)
Intermediate-Acting NPH (N) Insulin
Novolin N/Humulin N [Isohpane (NPH)]
Long-Acting Basal Insulin
Levemir (Detemir)
Lantus/Basaglar (Glargine U-100)
Toujeo (Glargine U-300)
Tresiba (Degludec)
Pre-Mixed Insulin
Novolin 70/30, Humulin 70/30, Humulin KwikPen (NPH + Regular)
Novolog Mix 70/30, Novolog FlexPen (Aspart Protamine/Aspart)
Humalog Mix 75/25, Humalog 50/50 (Neutral Protamine Lispro/Lispro)
Storage Requirements - Tresiba
In use: 56 days at room temp
Store product not in use in the refrigerator
Storage Requirements - Levemir, Novolin R, Novolin N, Toujeo
In use: 42 days at room temp
Store product not in use in the refrigerator
Storage Requirements - Humulin R, Humulin N
In use: 31 days at room temp
Store product not in use in the refrigerator
Storage Requirements - Lantus, Basaglar, Humalog, Novolog/Fiasp, Apidra
In use: 28 days at room temp
Store product not in use in the refrigerator
Storage Requirements - Novolog Pens 70/30
In use: 14 days at room temp
Store product not in use in the refrigerator
Storage Requirements - NPH Pens
In use: 14 days at room temp
Store product not in use in the refrigerator
Storage Requirements - NPH-Regular Mix Pens
In use: 10 days at room temp
Store product not in use in the refrigerator
Storage Requirements - Humalog 75/25 & 50/50 Pens
In use: 10 days at room temp
Store product not in use in the refrigerator
Biguanide MOA
SOA: pancreatic beta cells
MOA: decreased hepatic glucose, decreased GI absorption, increased insulin sensitivity
Benefit: less glucose production & release into blood; reduced gluconeogenesis, increased glucose uptake; increased GLUT4 transporters
Secretagogues: Sulfonylureas
SOA: pancreatic beta cells
MOA: increased insulin secretion
Benefit:
Secretagogues (Short-Acting): Glinides
SOA: pancreatic beta cells
MOA: stimulate increased insulin secretion
Benefit: decreased post-prandial glucose levels
TZDs - PPAR - GAMMA Receptor Activators
SOA:
MOA:
What insulin pen(s) can dial up to 160 units?
Toujeo Max and Tresiba U-200
Note: These pens have 2 unit dose increments
Diagnosis of Diabetes
FPG >/= 126 mg/dL
[OR]
Oral Glucose Tolerance test (OGTT) 2-h postload (75g) glucose >/= 200 mg/dL
[OR]
A1C >/= 6.5%
[OR]
Random plasma glucose >/= 200 mg/dL with classic symptoms of hyperglycemia or hyperglycemic crisis