ORAL MEDICATION Flashcards
What does sulfonylureas
increasing the production of insulin
How long works sulfonylureas
12-24h
Negatives about sulfonylureas
can cause hypo’s and weight gain
accelerates the breakdown of the pancreas
Examples of sulfonylureas
hypoglykemierende sulfamiden glibenclamide // daonil gliclazide //unidiamicron glimepiride //Amarylle glipizide // minidiab gliquidon // glurenorm
What does meglitinides
increasing the production of insulin
When to use sulfonylureas
very early stages of DT2
When to use meglitinides
very early stages of DT2
How long works meglitinides
a few hours
negatives about meglitinides
can cause hypo’s and weight gain
accelerates the breakdown of the pancreas
examples of meglitinides (gliniden)
repaglinide // novonorm
what does metformin
decreases the amount of sugar the liver produces
improvements on cholesterols
improvements on insulin sensitivity
Especially helpful for those with elevated fasting glucose levels most likely during the night (the liver is responsible for the elevated blood sugar levels overnight)
When to use metformin
DT2 and DT1
can be used in combination with insulin therapy
negatives about metformin
can’t be used by people with liver or kidney problems
examples of metformin
glucophage
metformax
metformine
what does thiazoladinediones
increase the sensitivity of the body’s muscle and fat cells to insulin
(the same effect can be gained by exercising
and losing weight)