ORAL MEDICATION Flashcards

1
Q

What does sulfonylureas

A

increasing the production of insulin

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2
Q

How long works sulfonylureas

A

12-24h

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3
Q

Negatives about sulfonylureas

A

can cause hypo’s and weight gain

accelerates the breakdown of the pancreas

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4
Q

Examples of sulfonylureas

A
hypoglykemierende sulfamiden
glibenclamide // daonil
gliclazide //unidiamicron
glimepiride //Amarylle
glipizide // minidiab
gliquidon // glurenorm
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5
Q

What does meglitinides

A

increasing the production of insulin

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6
Q

When to use sulfonylureas

A

very early stages of DT2

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7
Q

When to use meglitinides

A

very early stages of DT2

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8
Q

How long works meglitinides

A

a few hours

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9
Q

negatives about meglitinides

A

can cause hypo’s and weight gain

accelerates the breakdown of the pancreas

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10
Q

examples of meglitinides (gliniden)

A

repaglinide // novonorm

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11
Q

what does metformin

A

decreases the amount of sugar the liver produces
improvements on cholesterols
improvements on insulin sensitivity
Especially helpful for those with elevated fasting glucose levels most likely during the night (the liver is responsible for the elevated blood sugar levels overnight)

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12
Q

When to use metformin

A

DT2 and DT1

can be used in combination with insulin therapy

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13
Q

negatives about metformin

A

can’t be used by people with liver or kidney problems

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14
Q

examples of metformin

A

glucophage
metformax
metformine

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15
Q

what does thiazoladinediones

A

increase the sensitivity of the body’s muscle and fat cells to insulin
(the same effect can be gained by exercising
and losing weight)

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16
Q

when to use thiazoladinediones

A

DT2

17
Q

negatives about thiazoladinediones

A

risk of
liver problems
fluid retention
risk for people with a history of heart failure

18
Q

examples of thiazoladinediones

A

pioglitazone // actos

rosiglitazone

19
Q

what does alpha-glucosidase inhibitors

A

degestion blocker
alpha-glucosidase is the enzym that breaks down carbohydrates
it aids losing weight

20
Q

negatives about alpha-glucosidase inhibitors

A

abdominal pain
diarrhea
gas
THE SIDE EFFECTS ARE MORE THAN MOST PEOPLE WISH TO ENDURE

21
Q

examples of alpha-glucosidase inhibitors

A

acarbose

miglitol

22
Q

what does dpp-4 inhibitors

A

blocking the enzym that breaks down GLP-1
help the pancreas to release it’s stored up insulin when the blood sugar is elevated
decrease glucagon secretion from the pancreas
! promote growth an duplication of cells in the pancreas that produce insulin!
decrease apetite
slow the movement of food from the stomach into the intestines

23
Q

negatives about dpp-4 inhibitors

A

minimal!

cave kidney problems

24
Q

examples of dpp-4 inhibitors

A
sitagliptin // januvia
alogliptine // vipidia
linagliptine // trajenta
saxagliptine // onglyza
vildagliptine // Galvus