Oral Controlled Release Flashcards
Q1: What is a “Controlled Release” formulation?
It involves a formulation constraint on the release of a drug from the delivery system, including “targeted-release” and “constant-release” systems.
How does “Immediate Release” differ from “Controlled Release”?
Immediate Release has no formulation constraints, while Controlled Release regulates drug release for targeted or sustained delivery.
What are the benefits of controlled-release formulations?
They minimize toxicity, improve targeting, absorption, consistency in drug action, reduce waste, enable effective timing, and enhance patient compliance.
Define Cmax.
The maximum (peak) concentration of a drug in the blood.
What is the therapeutic window?
The range between the maximum therapeutic level and the minimum effective level.
