Oral cavity & Pharynx Flashcards
precancerous oral lesion that appears as white patches/plaques/non-removable
Leukoplakia
leukoplakia steps in formation
hyperplasia–>dysplasia–>carcinoma in situ–>invasive malignant tumor
other conditions not associated w/malignancy associated w/ leukoplakia
hyperkeratosis from chronic irritation
eg, dentures, tobacco, etc.
Tx of Precancerous lesions
should be surgically removed ;
cryotherapy & laser ablation have been used
Most common oral cancer
Squamous Cell Carcinoma
oral pigmented lesions
Melanoma
fluid-filled cavities w/mucous glands lining epithelium after mild oral trauma on the lower lip
Mucoceles
two forms of lichen planus
Reticular
Erosive
white lacy striations (wickham’s striae) or papules on buccal mucosa (no pain)
Reticular :ichen PLanus
Zones of tender erythema & painful ulcers surrounded by white, radiating striae
Erosive Lichen PLanus
Tx of Asymptomatic Lichen Planus
regular follow-up
Tx of Symptomatic Lichen Planus
manage pain & discomfort
topical + systemic corticosteroids, cyclosporines, retinoids
erythema of oral cavity w/creamy-white, curd-like patches. Fluctuating mouth / throat discomfort
Oral Candidiasis
Tx of Thrush on infants
cleans everything nipples, pacifiers
Nystatin suspension x 2wks until 2-3 days after resolution
refractory gentian violet or oral fluconazole
Tx of mild thrush in older children
<50% mucosal involvement:
Topical nystatin QID or
Clotrimazole lozenges 10mg 5-6 x a day
Tx of Severe Thrush in older children
> /= 50% oral mucosal &/or deep erosive / refractory
Fluconazole 6mg/kg po on 1st day, 3mg/kg x 7-14 days
Tx of Thrush in Adults
fluconazole 100mg PO x 7 day
Ketoconazole 200-400mg PO 7-14 days
Nystatin mouth ring 5mg swish before swallow
HIV+ Tx’d for longer
prodromal pain, burning, &/or tingling x 24 hrs, clusters of small vesicles on vermilion border which rupture/ulcerate/& crust in 24-48 hrs
Herpetic Gingivostomatitis
HSV-1
Diagnosis of Herpetic Gingivostomatitis
multinucleated giant cells on Tzanck smear
Tx of Herpetic Gingivostomatitis
Acyclovir200-800mg PO 5 x day for 7-10 days
Valacyclovit 1000mg PO BID 7-10 days
Tx of Herpetic Gingivostomatitis only effective if initiated w/in
24-48 hrs of prodromal Sx’s
Criteria suggesting Group A Streptococcus (GAS) “Strep Throat”
Fever (>100.4)
Anterior cervical LAD
No Cough
Tonsillar Exudate
Most common cause of pharyngitis
Viral agent
Cough, rhinorrhea &/or lack of exudate
Viral pharyngitis