Oral Board Prep Flashcards
Bleeding in early pregnancy: what 6 DDX do you consider?
- Pregnancy loss (Ectopic, SAB)
- UTI/Vaginal Infection
- Subchorionic hematoma/hemorrhage
- Cervical Abnormalities
- Molar Pregnancy
- Vaginal Trauma
How much should HCG rise in a viable pregnancy?
At least 33% if over 3000
48% if over 1500
Choices of management in an ectopic pregnancy
Medical: Methotrexate 50mg IM. Follow hCG on day 4 and 7. Rise on day 4 is expected, however must be at least 15% decrease on day 7. If not, follow with second dose of 50mg MTX. F/u weekly until hCG is neg.
Surgical: always offer. Go-to if bleeding or hemo unstable.
Patient teaching with methotrexate use?
No folic acid no NSAIDS
Decreased activity and pelvic rest
Wait 3 months before trying agin for pregnancy
SAB: definitation and management?
CRL >= 7mm and no heart beat
Gestational sac >= 25mm with no embryo.
Expectant management (may take up to 30 days)
Medical management: Mifepristone 200mg PO and then Misoprostol 800mcg vaginally. May repeat w/in 7 days if needed.
Surgical: D+C. Pelvic rest 1-2 weeks post SAB to prevent infection and promote healing. May try immediately for another pregnancy or immediately for BC.
RF for ectopic pregnancy?
IUD, previous ectopic. Hx of damage to FTs, smoking, hx of infertility, AMA, endometriosis.
RF for SAB?
Prior SAB, maternal chronic disease, toxins, substance use, infection, uterine anomaly, AMA
UTI in pregnancy. 2 medication options for 1st TM
Cephalexin (Keflex) - 250-500mg Q6hr for 5-7 days
Augmentin 875mg q12hr 5-7 days.
2nd TM? Nitrofurantoin 100mg q12hr 5-7 days.
BV treatment in pregnancy
Yeast tx in pregnancy
Metronidazole 500mg BID for 7 days
No PO azoles. Miconazole topical vaginally x7 days
Tx of G/C in pregnancy
G - x1 IM Ceftriaxone 500mg
C - 1G Azithromycin PO x1
Pt education and return precautions regarding Subchorionic hematoma/hemorrhag.
Most resolve on their own within a few weeks.
Beware for increased bleeding and s/s of labor (cramping, LBP, etc)
May decrease activity, pelvic rest, rhogam, serial US. If viable fetus, may do fetal surveillance?
RF for SCH?
Uterine irregularity, Hx of uterine infx, trauma, hx of EPL, IVF pregnancy or hypertension.
3 possible cervical abnormalities that could cause bleeding in early pregnancy
Friability - increased vascularity in pregnancy
Polyp
Malignancy
Molar pregnancy - RF, management
RF: very young or very old maternal, hx of molar pregnancy,
Tx with D+C. Monitor hCG at 48hrs and then every 1-2 weeks until neg.
WAIT 12mo to get pregnant again.