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Diabetes Mellitus > Oral antidiabetic Drugs And Insulin > Flashcards

Oral antidiabetic Drugs And Insulin Flashcards

1
Q

Biguanides

A

Metformin

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2
Q

Sulphonylureas

A

Gen. 1 - Chlorpropamide, Tolbutamide
Gen. 2 - Glipizide, Gliclazide, Glimperide, Glibenclamide

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3
Q

Meglitinides

A

Repaglinide
Nateglinide

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4
Q

Thioazoledinediones (PPAR-Gamma)

A

Torglitazone
Rosiglitazone
Pioglitazone - Only used now

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5
Q

GLP-1 Analogues

A

Exenatide
Liraglutide
Albiglutide
Dulaglutide

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6
Q

DPP-4 (Dipeptidyl peptidase) Inhibitors

A

Sitagliptin
Saxagliptin
Linagliptin
Vildagliptin

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7
Q

SGLT-2 Inhibitors

A

Canagliflozin
Dapagliflozin
Empagliflozin

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8
Q

Short acting Insulin

A

Regular insulin

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9
Q

Rapidly acting insulin

A

Lispro
Aspart
Glulisine

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10
Q

Intermediate acting Insulin

A

NPH
Lente

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11
Q

Long Acting insulin

A

Glargine
Detemir
Degludec

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12
Q

Metformin side effects

A

GI disturbances
Megaloblastic anemia (Vitamin B12 deficiency)
Lactic acidosis - rare
Weight loss/No change
No Hypoglycemia

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13
Q

Sulphonylureas side effects

A

Hypoglycemia
Weight gain
Chlorpropamide - Cholestatic Jaundice
- Disulfiram like reaction
- ^ ADH - Dilutional hyponatremia

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14
Q

Thioazoledinediones (PPAR-Gamma) Analogues:

A

Hepatotoxicity
Rosiglitazone - increases risk of MI
Pioglitazone - increased risk of bladder cancer
Contraindicated in cardiac patients and in Renal failure

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15
Q

Alpha glucosidase Inhibitors

A

Flatulence
GI Disturbances
May cause Hypoglycemia - eat sugar not food
Contraindicated in Inflammatory bowel disease

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16
Q

GLP-1 Analogues

A

Nausea, vomiting
Pancreatitis
Hypoglycemia (very low risk)
Increased risk of medullary cancer of thyroid

17
Q

DPP-4 Inhibitors side effects

A

Nasopharyngitis
Pancreatitis
Contraindicated in Renal failure except Linagliptin
No Hypoglycemia

18
Q

SGLT-2 Inhibitors

A

Urinary tract or Genital tract infection
Hypovolemia
Ketoacidosis
Reduce CV outcome and Mortality
Weight loss

Diabetes Mellitus (1 decks)

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