optional CIS Flashcards
leading cause of death of infants from 1 mo- 1 yr
SIDS
is SIDS a legitimate cause of death
yes
what is the most common finding in infants who died from SIDS
astrogliosis of the brainstem
sudden death in a child <1 yr old with no signs of SIDS, genetic/congenital disease is typically due to
infection
most common tumor of infancy
hemangioma
reddish brown cystic lesion measuring 6.2 cm in sacrococcygeal region of 1 mo old
most likely Dx
benign cystic teratoma
not malignant because tend to happen >4 mo old
4 y/o with thrombocytopenia and inc WBC
CBC with 20% blasts
most likely Dx?
B cell ALL
wilms tumor and metastatic neuroblastoma don’t generate large WBC counts why?
neuroectoderm neoplasms
20 mo old boy with distended abdomen, fever and weight loss
proptosis b/l
BP unremarkable
which of the following would be most useful in Dx?
because this is a neuroblastoma
serum catecholamines are most useful to Dx this
what is a good prognostic factor for a 20 mo old with metastatic neuroblastoma
TRKA expression
The 4S stage neuroblastoma is used for what age groups
only less than 1 yr old
7 y/o with small abdominal mass, aniridia, genital anomalies and mentally challenged
PAX6 deletions and WTI assays exhibit mutations
most likely in this child?
Wilms tumor
What are the 4 types of wilms tumors
sporadic
WAGR type
Denys Drash
Beck-wiedemann
classically and primarily CF was considered to be a disease of the
lower respiratory tract
lungs
what do most patients in the US with CF die from
cardiorespiratory disease
recurrent infections
gonadoblastomas are most commonly assoc with
denys drash syndrome
homicide on a death certificate means what
death was caused by other individual or entity
42 y/o obese male heavy smoker
died
proximal atherosclerotic plaques in main coronary aa and concentric ventricular hypertrophy
most likely COD? mechanism?
COD: ASCVD
mech: cardiac arrhythmia
if the brain tissue is extruded, lacerated and hemorrhagic than what does that tell you about the weapon
usually high velocity. not normally a handgun
what is fixed livor mortis
has not been moved, been there a while
how long does rigor mortis take
2-4 hours at room temp
what does a green patch in the right lower quadrant of a dead person suggest
bacterial decomposition
soot within the gun shot wound suggests what
close range, contact
describe exits vs entry in high velocity weapons
exit>entry for high velocity
exit=entry for regular
what type of gun is a revolver and semiautomatic
handguns
do long barrels or short barrels have higher velocity
longer barrels- higher velocity
what are smooth bore weapons
shot guns
what is algor mortis
cooling of the body
what is livor mortis
no more circulation
remaining vasculature sinks to the bottom
becomes fixed after 3-4 hours
what is putrefactive decomp
bacteria reduce body to gas and water
what is mummification decomp
very dry climates
body and soft tissue dehydrated
what is adipocere formation
body in water for a long period of time
saponification
skin erodes
what evidence cannot go in plastic bags? why?
biologic or organic
sun and water can degrade DNA
