optional CIS Flashcards

1
Q

leading cause of death of infants from 1 mo- 1 yr

A

SIDS

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2
Q

is SIDS a legitimate cause of death

A

yes

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3
Q

what is the most common finding in infants who died from SIDS

A

astrogliosis of the brainstem

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4
Q

sudden death in a child <1 yr old with no signs of SIDS, genetic/congenital disease is typically due to

A

infection

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5
Q

most common tumor of infancy

A

hemangioma

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6
Q

reddish brown cystic lesion measuring 6.2 cm in sacrococcygeal region of 1 mo old
most likely Dx

A

benign cystic teratoma

not malignant because tend to happen >4 mo old

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7
Q

4 y/o with thrombocytopenia and inc WBC
CBC with 20% blasts
most likely Dx?

A

B cell ALL

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8
Q

wilms tumor and metastatic neuroblastoma don’t generate large WBC counts why?

A

neuroectoderm neoplasms

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9
Q

20 mo old boy with distended abdomen, fever and weight loss
proptosis b/l
BP unremarkable
which of the following would be most useful in Dx?

A

because this is a neuroblastoma

serum catecholamines are most useful to Dx this

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10
Q

what is a good prognostic factor for a 20 mo old with metastatic neuroblastoma

A

TRKA expression

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11
Q

The 4S stage neuroblastoma is used for what age groups

A

only less than 1 yr old

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12
Q

7 y/o with small abdominal mass, aniridia, genital anomalies and mentally challenged
PAX6 deletions and WTI assays exhibit mutations
most likely in this child?

A

Wilms tumor

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13
Q

What are the 4 types of wilms tumors

A

sporadic
WAGR type
Denys Drash
Beck-wiedemann

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14
Q

classically and primarily CF was considered to be a disease of the

A

lower respiratory tract

lungs

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15
Q

what do most patients in the US with CF die from

A

cardiorespiratory disease

recurrent infections

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16
Q

gonadoblastomas are most commonly assoc with

A

denys drash syndrome

17
Q

homicide on a death certificate means what

A

death was caused by other individual or entity

18
Q

42 y/o obese male heavy smoker
died
proximal atherosclerotic plaques in main coronary aa and concentric ventricular hypertrophy
most likely COD? mechanism?

A

COD: ASCVD
mech: cardiac arrhythmia

19
Q

if the brain tissue is extruded, lacerated and hemorrhagic than what does that tell you about the weapon

A

usually high velocity. not normally a handgun

20
Q

what is fixed livor mortis

A

has not been moved, been there a while

21
Q

how long does rigor mortis take

A

2-4 hours at room temp

22
Q

what does a green patch in the right lower quadrant of a dead person suggest

A

bacterial decomposition

23
Q

soot within the gun shot wound suggests what

A

close range, contact

24
Q

describe exits vs entry in high velocity weapons

A

exit>entry for high velocity

exit=entry for regular

25
what type of gun is a revolver and semiautomatic
handguns
26
do long barrels or short barrels have higher velocity
longer barrels- higher velocity
27
what are smooth bore weapons
shot guns
28
what is algor mortis
cooling of the body
29
what is livor mortis
no more circulation remaining vasculature sinks to the bottom becomes fixed after 3-4 hours
30
what is putrefactive decomp
bacteria reduce body to gas and water
31
what is mummification decomp
very dry climates | body and soft tissue dehydrated
32
what is adipocere formation
body in water for a long period of time saponification skin erodes
33
what evidence cannot go in plastic bags? why?
biologic or organic | sun and water can degrade DNA