Optho Flashcards
risk factors for cataracts
DRATS-MUD Dm Rtx Atopy Trauma Steroids Myotonic dystrophy Uveitis Downs
MCC reversible blindness
cataracts
PC cataracts
painless gradual decrease VA glare halos around lights at night dimness decrease colour intensity- CLOUD/ BLURRY VISION monocular diplopia
3 types of cataracts
- cortical
- nuclear sclerosis
- posterior subcapsular
cortical cataracts associated with
DM and aging
nuclear sclerosis a/w
aging
NB extra facts for nuclear sclerosis
brunescent-yellowish
SECOND SIGHT PHENOMENA
posterior subcapsular=
FROSTED GLASs; posterior adjacent to the capsule
a/w DRATS-intraocular inflammation
diagnostic tests for cataracts
- VA
- Opthalmoscope- red reflex
- Slit lamp
name of surgery for cataracts
phacoemulsification: sutureless 3mm incision AND place intraocular lens
complications of cataracts surgery
RARE C-GERD Cystoid macular edema Glaucoma Endopthalmitis Retinal detachment Dislocated IOL
decrease aqueous production drugs
AB-D-P
Alpha agonists- AD, brimonidine
Betablockers- timolol
Diuretics
increase aqueous outflow drugs
Cholinomimetics- pilocarpine, carbachol
PG’s- latanoprost
BOTH: decrease aqueous production
increase aqueous outflow
ALPHA AGONISTS
definition of glaucoma
- optic nerve damage
- visual field defect
- +/- IOP
optic nerve head damage in glaucoma
loss of ganglion cells and axons, thus loss of neuroretinal rim–> ENLARGEMENT of optic disc= cupping
EXTRA: spectrum of optic nerve damage
- pallor and cupping of optic disc: small paracentral scotoma
- concentric enlargement: arcuate defect
- superior expandion: arcuate defect
- advanced total cupping: temporal central island
different types of glaucoma
- POAG
- Low tension glaucoma
- Ocular HTN
- Chronic closed angle glaucoma
- secondary glaucoma- rubeotic
rubeotic glaucoma
neovascularisation secondary to DM
low tension glaucoma
glaucomatous disc with normal IOP
who is at risk for low tension glaucoma
- women>60
- secondary vasc insuff
ocular HTN
normal disc with increase IOP
chronic closed angle glaucoma diagnosis based off of….
appearance of drainage angle
trabecular meshwork covered by lens
similar glaucomatous disc with increased IOP
risk factors for POAG
- increase IOP
- increase age
FEMD
family hx
ethnicity- afrocarribean
myopia
DM
diagnosis of glaucoma
- VA– advanced
- Pupil rxn- RAPD with asym optic n damage
- gonioscopy- angle- open or closed
- Goldmann tonometry– applanation
- fundosocpy– cupping
- Humphrey visual fields
monitoring disease progression in glaucoma
- Fundoscopy
- Humphrey vf
treatment of glaucoma
PG or Betablocker– individually then together, then CA inhibitor, then
Trabeculectomy
risk factors to becoming blind with glaucoma
severity at presentation
LE
rate of progression
dry ARMD
RPE atrophy– coalescence of depigmented RPE= clump of focal hypo/hyperpigmentation
bruch membrane
area separating inner choroidal vessels from RPE
drusen
white deposits/lipofuscin between RPE and photoreceptors
wet ARMD secondary to
- inflammation
- submacular haemorrhage
- macular edema/exudate
END STAGE ARMD
GEOgraphical atrophy
SCARRING
IRREVERSIBLE loss of central vision
risk factors for ARMD
- female
- increasing age
- smoker
- caucasian
- blue eyes
- family history
PC ARMD
- metamorphopsia
- central scotoma
- reading difficulties
2 types of wet
occult
classic
classic wet ARMD
well defined leakage
occult wet ARMD
mottled or ill-defined leakage
dx ARMD
- VA/VF
- Amsler grid
- OCT
- Fluorescin angio
dry ARMD tx
low vision magnifying aids
social services
wet ARMD
intravitreal VEG-F– 3 months, then maintenance
- 2/3= stabilize
- 1/3= improve
exogenous antioxidant vitamins
- vits C, E
- Beta-carotene
- Zn
macular pigments
- lutein
- zeaxathin
risk factors for DM retinopathy
- CV risk factors
- duration
- ethnicity– black
- anaemia
- puberty
- prego
microvascular pathophysiology for DM
capillary leakage–> ischaemia–> vascular occlusion
parasite loss
endothelial damage
neuroretinal pathophysiology for DM
impaired neurotransmission–> apoptosis
late PC of DM
DECREASE VA= LATE
- macular edema= mcc vision loss
- VH
- retinal tractional detachment
clinical findings for DM retinopathy
- VA
- anterior segment (3)
- dilated fundal exam (3)
anterior segment findings DM retinopathy
- IRIS NEOVASC
- glaucoma- rubeotic- increase IOP
- cataracts- lens
dilated fundal exam DM retinopathy
- DM retinopathy
- vascular occlusions
- AION
dx of DM retinopathy
EXACT SAME AS ARMD (still do amsler in case of metamophopsia)
tx of DM retinopathy
- systemic- cv rf’s
- screening- annual, vital
- laser tx
- surgery= vitrectomy
- intravitreal Veg-F
laser tx indicated for…
- maculopathy
2. proliferative
maculopathy benefit from laser tx
- closes leaky vessels
- stimulates RPE pump
- decreases edema
- stabilizes vision
proliferative benefit from laser tx
- destroys ischaemic retina
- decreases angiogenic GFs
focal/ grid laser tx….
MACULOPATHY
x central field
x burn spread–> foveal burn/blind spot
panretinal photocoagulation
x cannot drive
x peripheral field
x night vision
x painfull
sx in DM indications
VITRECTOMY
- persistent VH
- tractional RD
intravitreal veg-f for maculopathy
- decrease edema
- increase vision
intravitreal veg-f for retinopathy
- regress new vessels
- clear VH
combined laser and intravitreal tx DM
- DIABETIC MACULAR EDEMA– diffuse OR focal
- PROLIF.D.R.– with VH or DME
background DR
microaneurysms
dot and blot haemorrhages
retinal edema
hard exudates
micro aneurysms are secondary to….
proliferation of pericytes
preproliferative DR
cotton wool spots intra-retinal microvascular abnormalities venous changes extensive RHs arterial changes
cotton wool spots
secondary to impaired axonal transport–> ischaemia
TEMPORARY
intra-retinal microvascular abnormalities
arteriolar-venular shunts
capillary occlusion adjacent
venous changes
sausaging/beading
omega sign
arterial changes
attenuation of vessels
proliferative DR
ischemia–> VEGF–> neovasc- NVD/NVE–> RH–> traction vitreous= RD–> fibrosis
advanced diabetic eye
rubeotic glaucoma
persistent VH
tractional RD– fibrotic bands
maculopathy Diabetes
macular edema= variable visual impairment
macular ischaemia= SEVERE visual impairment
maculopath in DM can be
mixed
diffuse
focal
ischaemic
differential for leucocoria
- cataracts
- coloboma
- toxicariasis
- coloboma
RETINA - ROP
- retinal dysplasia
- retinal detachment
- COATS DISEASE
- primary persistent vitreous
- corneal opacity
COATS DISEASE
exudative retinal telangiectasias
3 parts of uvea
- iris
- ciliary body
- choroid
anterior uveitis
iritis
posterior uveitis
choroiditis
uveitis
- RA
- JIA
- sarcoidosis
- HLA–B27
keratoconus
abnormal conical shape of cornea–> astigmatism
cause of keratoconus
MCC= SPORADIC
- downs
- contacts
atrophy
keratoconus a/w
breaks in
- bowmans membrane
- descemet membrane
munsons sign
bulging of lower eyelid when looking downwards with a keratoconus
risk factors for retinal vein occlusion
atherosclerosis
HTN
DM
glaucoma
fundoscopy retinal vein occlusion
blood and thunder; diffuse all 4 quads
venous engorgement
optic disc swollen
macular edema
tx retinal vein occlusion
intra-lesional anti-veg-F
- laser
risk factors for retinal artery occlusion
EMBOLI
THROMBUS
GCA
timing for retinal artery occlusion
2hours
fundoscopy for retinal artery occlusion
cherry red macula paleretina boxcarring-- narrowing arterioles cotton wool spots hollenhorst plaques
tx for retinal artery occlusion
globe massage
acute angle closure tx
tx keratoconus
contact lens
CORNEAL TRANSPLANT
most common site for tear for RD
SUPEROTEMPORAL RETINA
risk factors for RD
- age
- myopia
- DM
- trauma
photopsia—
tears in vessel–> blood drop into vitreous=
HAZY VISION
3 types of retinal detachment
- rhegmatogenous
- tractional
- exudative
rhegmatogenous RD
hole in the neurosensory retina= MC
tractional RD
pull neurosensory away from RPE
exudative
damage RPE–> subretinal fluid
2 similar treatments for rhegmatogenous and tractional RD
SCLERAL BUCKLE sx
VITRECTOMY
additional tx for rhegmat. RD
- cryotx
- laser tx
- pneumatic retinopexy
additional tx for tractional RD
- membrane removal
- intraocular gas
- silicone oil
inflammation difference between chalazion and hordoleum
chalazion= granulomatous hordoleum= acute inflammation
other name for chalazion=
meibomian cyst
other name for hordoleum=
stye
cysts of zeis and moll
zeis= modified sweat gland
moll= modified sebaceous gland of external eyelid
SMALL WHITISH OPAQUE CHRONIC PAINLESS NODULES
TX cysts of zeis and moll
simple incision
tx molluscum contagiosum
shave excision
trichiasis secondary to
blepharitis
SJS
trauma/ burns
tx trichiasis
lubricant
electrolysis
eyelash pluck cryotx
blepharitis two types
- staph– ulcerative and dry scales
2. seborrheic– NO ulcers, greasy scales
toothpaste sign
blepharitis– discharge with pressure
tx blepharitis
warm compresses and baby shampoo
antibiotics
short course steroids
entropion diagnosis
forced lid closure– lid rolls inwards
causes of entropion
- involution=MC
- cictricial
- spastic
- congenital
involution as cause of entropion
= MC, AGING–> laxity
causes of cicatricial entropion
SC-SHOTT SJS Chemical burns Surgery Herpes zoster Ocular pemphigoid Trauma Trachoma
ocular pemphigoid–>
cictricial entropion:
older patients with chronic ulcers and adhesions
spastic entropion–>
orbicularis oculi irritation
causes of ectropion
- involution
- cicatricial
- mechanical
- paralytic
- congenital
mechanical cause of ectropion
WEIGHT of tumor/ edema/ fat on the eyelid
paralytic cause of ectropion
CN7
diagnosis of ectropion
SNAPBACK TEST– pull eye inferiorly– lid remains away from globe
treatment of entropion and ectropion
LUBE
SURGERY
causes of ptosis
MCC= age related dehiscence
congenital
acquired
acquired causes of ptosis
neurogenic- CN3, Horners
aponeurotic- rupture LPS
myogenic- mg, myotonic dystrophy
mechanical- inflam/tumor/vascular
lagopthalmos
incomplete closure of eyelids–> CN7 palsy
bells phenomeon
tighten eyes shut–> globes don’t go up anymore
= LAGOPHTHALMOS positive
treatment of lagopthalmos
lubricants
tape eyelids
lateral tarsorrhaphy
causes of blepharospasm
PARKINSONS
idiopathic
PYOGENIC
benign tumors of eyelid
- papilloma
- seborrheic keratosis
- keratocanthoma
- naevi
- capillary haemangioma
- xanthelasma
malignant tumors of eyelid
- BCC
- SCC
- melanoma
- meibomian cell ca
pre-auricular lad– eye lid tumor
SCC
symptoms of thyroid eye disease
- red/ irritated/ discomfort
- wide eye staring
- diplopia
- decrased vision
signs of thyroid eye disease
FULLNESS conjunctival hyperemia conjunctival edema= chemosis lid retraction lid lag resisted eye movement optic neuropathy
dx thyroid eye disease
thyroid– TFTS, TPO
CT ORBIT– enlarged extraocular muscles– XS soft tissue and normal tendon
dx optic neuropathy secondary to thyroid eye disease
- VA/VF
- fundoscopy
- pupils
- colour vision
tx optic neuropathy secondary to thyroid eye disease
orbital decompression
strabismus sx
lid retraction sx
tx thyroid eye disease
- lubricants
- NSAIDs
- prisms– diplopia
- steroids
- immunosup
- radiotherapy
- surgery
lens for esotropia and exotropia
convex
different types of squints
esotropia
exotropia
hypertropia
hypotropia
different types of ambylopia
strabismic
stimulus deprivation– patho. obstacle
anisometropic– unequal refractive errors
ametropic– bilateral high refractive errors
window to correct lazy eye=
8 years old
orbital tumors MCC=
LYMPHOMA rhabdomyosarcoma capillary haemangioma carcinoma of lacrimal duct optic nerve glioma optic nerve meningioma mets
amaurosis fugax is secondary to…
arterial embolism
GCA
non-arteritic anterior ischaemic neuropathy
sudden painless monocular MILD-MOD vision loss
RAPD
altitudinal field loss
risk factor for N-AION
HYPERTENSION
ESR for NON-AION
NORMAL ESR
signs of GCA
- scalp tenderness
- tender nodular NON-pulsatile temporal artery
- RAPD
- swollen optic disc and pale
dx GCA
FBC
ESR, CRP
Biopsy
vitrehous haemorrhage has no…
NO red reflex
NO view of retina
vitreous haemorrhage causes
MCC= DM
- retinal vein occlusion
- trauma
PC optic neuritis
sudden LOV
PAIN on movement
dull ache
signs of optic neuritis
RAPD
pale swollen optic disc
early= colour desaturation
papillitis or retrobulbar
3 big causes optic neuritis
MS
idio
viral
syneresis
CHRONIC flashes and floaters
MCC flashes and floaters=
posterior vitreous detachment= 70%
ASYMPT.
NO retinal tear
NO RD
other causes for flashes and floaters
- PVD
- migraine
- VH
- posterior uveitis
retrobulbar optic neuritis
NORMAL optic disc
treatment of GCA
IV methylprednisolone
60-80mg prednisone
—-> 5-10mg prednisone; 1-2years
neurologic causes of diplopia
CN3,4,6 SHTT MD. Stroke HTN Tumor Trauma MS DM
mechanical causes of diplopia
- thyroid eye disease
- orbital cellulitis
- blow out fracture
- lymphoma
distorted vision causes
ARMD
macular hole
retinal vein occlusion
tx of conjuncitivitis
chloramphenicol– drops every day for 2-3wks
Sodium chromoglycate- qds +/- olapatadine
episcleritis
localized or diffuse redness
SPARING** palpebral conjunctiva
tx episcleritis
RESOLVE SPONTANEOUSLY
—> oral NSAIDs or topical steroids
iritis PC
PAINFUL eye, increasing in severity
photophobia
circumcorneal redness
constricted pupil
tx iritis
INTENSIVE steroids and mydriatic–> cyclophentolate
marginal keratitis
= peripheral corneal ulcer
tx marginal keratitis
steroid/ Abx combo
tx herpes simplex keratitis
3% acyclovir 5x/day for 2-3wks
infective keratitis– bacterial:
ofloxacin OR
vancomycin + ceftazidime