Opthalmology Flashcards
What are the features of an afferent pupillary defect?
No direct response but in tact consensual response
No contralateral consensual response
Dilation on moving light from normal to abnormal eye
What are the causes of a Marcus Gunn pupil?
Optic neuritis
Optic atrophy
Retinal disease
What are the features of an efferent pupilliary defect?
Dilated pupil which does not react to light
Initiates consensual response in contralateral eye
Opthalmoplegia
Ptosis
What is the cause of an efferent pupillary defect?
3rd nerve palsy
What are the differentials for a fixed dilated pupil?
Mydriatics e/g/ tropicamide
Iris trauma
Acute glaucoma
CN3 compression
What are the features of Horner’s syndrome?
PEAS
Ptosis
Enopthalmos
Anhydrosis
Small pupil
What are the causes of Horner’s syndrome?
Central, pre-gang, post-gang
Central - MS, LMS
Pre-gang - Pancoast’s tumour (T1), trauma due to CVA insertion
Post-gang - Cav sinus thrombosis, CN3,4,5,6 palsies
What are Argyll Robertson pupils and what causes them?
Small irregular pupils which accomodate but dont react to light.
DM
Quaternary syphillis
What are the features of optic atrophy/neuropathy?
Reduced acuity and colour vision
Central scotoma
Pale optic disc
RAPD
What are the causs of optic atrophy/neuropathy?
CAC VISION
n.b. MS and glaucoma commonest
Congenital - CMT, Leber’s Hereditary optic neuropathy, retinitis pigmentosa
Alcohol etc. - Lead, B12 def
Compression - Neoplasia, glaucoma, Pagets
Vascular - DM, GCS, VTE
Inflamm - MS
Sarcoid
Infection - Zoster, syphillis, TB
Oedema - papilloedema
Neoplastic infiltrates (lymphoma/leukaemia)
What might be the history findings of red eye?
Vision - blurred, diplopia, scotoma, floaters, flashes
Sensation - irritation, pain, itching, photophobia, FB
Apperaance - red +- lump
Discharge - watery, sticky, stringy
What are the signs of serious disease in a patient with red eye?
Photophobia
Visual impairment
Corneal fluorescein staining
Abnormal pupil
What are the key examination questions in red eye?
Is acuity affected?
Is the globe painful?
Are the pupils equal and reactive?
Are the cornea in tact or cloudy?
Comment on each of the following in acute glaucoma:
Pain Photophobia Acuity Cornea Pupil IOP
Pain +++ Photophobia nil Acuity reduced Cornea hazy/cloudy Pupil large IOP raised
Comment on each of the following in anterior uveitis:
Pain Photophobia Acuity Cornea Pupil IOP
Pain ++ Photophobia ++ Acuity reduced Cornea normal Pupil small IOP normal
Comment on each of the following in conjunctivitis:
Pain Photophobia Acuity Cornea Pupil IOP
Pain +/- Photophobia + Acuity normal Cornea normal Pupil normal IOP normal
What is the pathology and thus of acute closed angle glaucoma?
Blocked drainage of aqueous humor from anterior to posterior chamber via the canal of Schlem
Pupil dilatation worsens the blockage
IOP rises from 15-20 ->60
What are the risk factors for acute closed angle glaucoma
Hypermetropia (long sightedness) Shallow ant chamber Female FH Old age Drugs - anticholinergics, TCAs, anti-histamines
What are the symptoms of acute glaucoma?
Severe pain with N/V
Reduced acuity with blurred vision
What are the examination findings of acute glaucoma>
Cloudy cornea with circumcorneal injection
Fixed, dilated, irregular pupil
Raised IOP makes eye feel hard
What is the acute management of acute glaucoma?
Pilocarpine drops - miosis opens blockage
Topical beta blockade (timolol) - reduces aqueous formation
Acetazolamide 500mg IV state - reduces aqueous formation
Analgesia
Antiemetics
What is the pathophysiology of anterior uveitis?
Uvea includes iris, ciliary body and choroid (vascular layer)
These structuresbecome inflamed in ant uveitis
What are the symptoms of anterior uveitis?
Acute pain and photophobia
Blurred vision
What are the examination findings of anterior uveitis?
Amall pupil initially ->irregular later on
Circumcorneal injection
Hypopyon - pus in ant chamber
What is Tablot’s test and when is it positive?
Assesses pain on convergence and is seen in anterior uveiitis
What are the associations with ant uveitis?
Seronegative arthropathies - AnkSpon, psoriatic, Reiters Stills disease IBD Sarcoid Bechets Various infections
What is the management of anterior uveitis?
Prednisolone drops
Cyclopentolate drops dilate the pupil and prevent adhesions forming between iris and lens
How does episcleritis present and what causes it?
Localised reddening which can be moved over the sclera
Painless/mild discomfort
Acuity is preserved
Usually idiopathic
How do you treat episcleritis?
Topical or systemic NSAIDs
How might scleritis present?
Severe pain worse on movement
Generalised scleral inflammation (vessels wont move unlik episcleritis)
Conjunctival oedema (chemosis)
What are the common causes of scleritis?
GwP
RA
SLE
Vasculitides
How is scleritis managed, and what is an important complication to note?
Corticosteroids or immunosuppressants
Scleromalacia (thinning) may precede globe perforation
What are the presenting features ofconjunctivitis?
Often bilateral with purulent discharge
Discomfort
Conjunctival injection (vessels may be moved over sclera)
Acuity responses and cornea are unaffected
What are the causes of conjunctivitis?
Adenovirus
Bacterial - staph, chlamydia, gonogoccal
ALlergic
What is the treatment for conjunctivitis?
Chloramphenicol ointment if bacterial
Antihistamine drops if allergic
HOw would you investigate a corneal abrasion?
Under a slit lamp with fluorescein stain which marks the defect green
What would you give for a corneal abrasion?
Chloramphenicol prophylaxis
What are the features of corneal abrasion?
Pain
Photophobia
Blurring
What are the causes of corneal inflammation?
Bacterial, herpes, fungi, RA
What are the features of corneal inflammation?
Pain Photophobia COnjunctival hyperaemia Reduced acuity White corneal opacity
What is the main risk factor for corneal inflammation?
Contact lenses
How would you investigate corneal inflammation?
Slit lamp and fluorescein
What is the management of corneal inflammation
Immediate referral Smears and cultures Abx/aciclovir drops Mydriatics ease photophobia Steroids worsen symptoms