OPTHA DRUGS

Question 1

Prostoglandin Analogues

Example and mechanism

SE’s

Answer 1

Lantanoprost

Increased uveoscleral outflow

Pigmentation of eye Increased eyelash length

Question 2

Beta Blockers

Example and Mechanism

SE’s

Answer 2

Timolol/Betaxolol

Reduces aqueous production

Avoid in Asthmatics or Heart block patients

Question 3

Sympathomimetics

Example and Mechanism

SE’s

Answer 3

Brimonidine

Reduces production and increases outflow

Do not give with MAOI’s or TCA’s

Hyperaemia

Question 4

Carbonic Anhydrase Inhibitors

Example and Mechanism

SE’s

Answer 4

Dorzolamide

Reduces Aqeous production

Sulphonamide like reactions

Question 5

Parasympathomimetic (Miotics)

Example and Mechanism

SE’s

Answer 5

Pilocarpine

Increases uveoscleral outflow

Constricted Pupil
Headache
Blurred Vision