Opioids: Clinical Application Flashcards

1
Q

Morphine

A

high efficacy

natural agonist

mod-sev pain - 1st line tx

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2
Q

Hydromorphone

A

high efficacy

semi-synthetic agonist

severe pain - 1st line tx

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3
Q

Methadone

A

high efficacy

synthetic agonist

severe pain - 1st line tx

used in detox for opioid addiction

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4
Q

Fentanyl

A

high efficacy

synthetic agonist

mod-sev pain, esp chronic and breakthrough pain - 1st line

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5
Q

Meperidine

A

high efficacy

synthetic agonist

mod-sev pain - 2nd line

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6
Q

Codeine

A

low-medium efficacy

prodrug

mild-mod pain, antitussive

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7
Q

Hydrocodone and Oxycodone

A

low-med efficacy

semi-synthetic agonist

mild-mod pain

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8
Q

Buprenorphine

A

mixed semi-synthetic agonist

mod-sev pain

tx for opioid addiction

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9
Q

Pentazocaine

A

synthetic mixed agonist and antagonist

mod-modsev pain

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10
Q

Naloxone

A

opioid antagonist

tx of acute opioid toxicity

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11
Q

Dextromethorphan

A

synthetic opioid isomer

non-analgesic anti-tussive

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