Opioids: Clinical Application Flashcards
Morphine
high efficacy
natural agonist
mod-sev pain - 1st line tx
Hydromorphone
high efficacy
semi-synthetic agonist
severe pain - 1st line tx
Methadone
high efficacy
synthetic agonist
severe pain - 1st line tx
used in detox for opioid addiction
Fentanyl
high efficacy
synthetic agonist
mod-sev pain, esp chronic and breakthrough pain - 1st line
Meperidine
high efficacy
synthetic agonist
mod-sev pain - 2nd line
Codeine
low-medium efficacy
prodrug
mild-mod pain, antitussive
Hydrocodone and Oxycodone
low-med efficacy
semi-synthetic agonist
mild-mod pain
Buprenorphine
mixed semi-synthetic agonist
mod-sev pain
tx for opioid addiction
Pentazocaine
synthetic mixed agonist and antagonist
mod-modsev pain
Naloxone
opioid antagonist
tx of acute opioid toxicity
Dextromethorphan
synthetic opioid isomer
non-analgesic anti-tussive