Opioid Kinetics (selected) Flashcards

1
Q

Morphine

A
Lipid insoluble (sm bbb)
Nl doses dont accumulate in tissue
Metab: glucuronidation in 1st pass - 50% to morphine-3-glucoronide, 15% to morphine-6-glucuronide "M6G" (pharm effects)
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