Opiod Toxicity Flashcards
1
Q
What 2 things may indicate opioid toxicity
A
- Unable to maintain airway
OR - Sp02% <92% on RA
2
Q
What is the initial Mx for Adult uncomplicated IV opioid toxicity?
A
- Airway Ventilation
- Naloxone 800mcg IM
- Repeat once @ 10/60
3
Q
If adequate response to IV opioid toxicity what is the next Mx?
A
- Consider referral
4
Q
If an inadequate response to IV opioid toxicity what is the next Mx?
A
- Transport
- Consider SGA
5
Q
What is the Mx for ADult complex opioid toxicity
A
- Narcan 100mcg IV
- Repeat @ 2/60
- Max 2000mcg
- Targeting return of adequate ventialtion (SAT -1 is appropriate in AV care)
- If no IV access: Naloxone 400mcg IM
- Consider SGA
6
Q
What is considered complex opioid toxicity?
A
- Prescription opioids
- Polydrug toxicity
- Iatrogenic
- Unknown
7
Q
What is rebound opioid toxicity?
A
- Short half life of Narcan can lead to potent opioids antagonising opiod receptors leading to CNS depression
8
Q
What are some signs of opioid toxicity?
A
- Respiratory depression (Sp02% < 92% on room air) / Apnoea
- Unable to maintain airway
- CNS depression
- Miosis
9
Q
What are the care objectives of Opioid toxicity
A
- Airway patency and adequate ventilation
- Reverse opioid action sufficiently to permit adequate spontaneous respiration without causing opioid withdrawal
10
Q
What is the Naloxone dose for an Opioid-naive paediatric?
A
- 10mcg/kg (Max 800mcg)
- Repeat once @ 10minutes
11
Q
What is the naloxone dose for an opioid-dependent Paediatric?
A
- Naloxone 1-2mcg/kg (Max 100mcg)
- repeat once @ 10/60
12
Q
What are some complication of Opioid toxicity
A
- Aspiration Pneumonitis
- Pressure injury/rhabdomyolysis
- Cardiac Arrest due to prolonged hypoxia
