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Drugs > Opiate analgesia > Flashcards

Opiate analgesia Flashcards

1
Q

Morphine onset

A

IV – 1-2 minutes
IM – 30-60 minutes

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2
Q

Morphine duration

A

3-4 hours

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3
Q

Morphine side effects

A
  • Decreased pulse and resp. rate
  • Bronchoconstriction
  • Nausea
  • Vomiting
  • Hallucinations
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4
Q

Morphine dose

A

0.05-0.1mg/kg

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5
Q

Diamorphine onset

A

1-2 minutes

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6
Q

Diamorphine duration

A

90 minutes

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7
Q

Diamorphine side effects

A
  • Decreased pulse and resp rate.
  • Bronchoconstriction
  • Nausea
  • Vomiting
  • Hallucinations
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8
Q

Diamorphine dose

A

IV – 5-10mg
Epidural – 2.5-5mg

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9
Q

Fentanyl onset

A

2-5 minutes

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10
Q

Fentanyl duration

A

30-60 minutes

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11
Q

Fentanyl side effects

A
  • Decreased pulse and resp rate.
  • Bronchoconstriction
  • Nausea
  • Vomiting
  • Hallucinations
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12
Q

Fentanyl dose

A

1-100µg/kg

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13
Q

Alfentanil onset

A

90 seconds

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14
Q

Alfentanil duration

A

5-10 minutes

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15
Q

Alfentanil side effects

A
  • Nausea
  • Vomiting
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16
Q

Alfentanil dose

A

IV – 10-50µg/kg
Infusion – 0.5-1µg/kg/min

17
Q

Remifentanil onset

A

1-3 minutes

18
Q

Remifentanil duration

A

Lasts duration of infusion (with half life of 5-14 minutes when stopped)

19
Q

Remifentanil side effects

A
  • Decreased resp rate.
  • Bradycardia
  • Nausea
  • Vomiting
20
Q

Remifentanil dose

A

Infusion – 0.0125-1µg/kg/min

21
Q

Pethidine onset

A

5 minutes

22
Q

Pethidine duration

A

1-2 hours

23
Q

Pethidine side effects

A
  • Decreased pulse and resp rate
  • Hallucinations
  • Nausea
  • Vomiting
24
Q

Which drug is used for opiate analgesia reversal?

A

Naloxone

25
Q

Naloxone onset

A

60 seconds

26
Q

Naloxone duration

A

20 minutes

27
Q

Naloxone side effects

A

Ventricular dysrhythmia

28
Q

Naloxone dose

A

Analgesia reversal – 0.1-0.2mg
Opiate overdose – 0.4-2mg IV/IM/SC

29
Q

Why must great care be taken to monitor a patient following Naloxone administration?

A

Naloxone can wear off before the opiate drug wears off

30
Q

When would further doses of Naloxone may be required?

A

If respiratory function begins to deteriorate again

Drugs (5 decks)

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