Ophthalmology (Exam 1) Flashcards
How are MMPs involved in corneal ulceration?
Secreted by epithelial and stromal cells, also invading microorganisms
Involved in degradation of ECM and BM
What is neurotrophic keratitis?
How is it tx?
Corneal innervation dysfunction
Tx: abx (TS), serum, GFs, antivirals (if herpes)
How is a simple corneal ulcer treated?
T Abx (BNP, erythromycin, tobramycin) Atropine to stabilize vascular endothelium
How is a complicated (non-healing) corneal ulcer treated?
TS abx
Systemic antiinflammatory
Serum
*Refer
What are indolent ulcers?
How are they treated?
Superficial ulcer with redundant epithelium/nonadherence
Debride if superficial
Refer for diamond burr/grid
What happens if grids are used in cats?
Sequestrums
NEVER DO THIS
When is surgical therapy indicated in corneal ulcers?
Depth >2/3, melting, risk of rupture
What is a corneal sequestrum?
How is it treated?
Painful, brown pigmented plaque d/t degradation of collagen
Typically in cats
Medical if vascular
Surgery if avascular
What is pigmentary keratopathy?
How is it treated?
Progressive following injury to cornea
Lubrication
T steroid
Cyclosporine/tacrolimus
What is pannus?
How is it treated?
Chronic superficial keratitis with inflammatory basis
GSD, Greyhound
Lifelong tx required T steroid (weaned off) Cyclosporine/tacrolimus Avoid UV light
What is corneal dystrophy?
How is it treated?
Hyperlipidemia in the center of the cornea
Only painful in Shelties
Lubrication
Cyclosporine/tacrolimus
*NO STEROIDS
What is calcium keratopathy?
How is it treated?
Mineral accumulation in the center of the cornea
Med: Lubricant
T abx
EDTA
Sx: diamond burr / needle /TCA
conjunctival graft
What is florida keratopathy?
How it treated?
Round and white stromal opacities
No treatment required
What is eosinophilic keratitis?
How is it diagnosed?
How is it treated?
Eosinophilic white plaque lesion in cats, associated with FHV
Dx: cytology for eos
abx
T steroids
How is immune keratitis treated?
T steroids
Cyclosporine/tacrolimus