Ophthalmology Flashcards
(88 cards)
What nerve causes a RAPD?
CN2, the optic nerve
What will you see in RAPD?
Affected eye = no direct response to light, consensual response intact.
Swinging light test gives apparent dilation when moving to the pathological eye
What nerve causes an efferent defect?
CN3, occulomotor
What are the types of 3rd nerve palsy?
Surgical = Compresses the outer fibres where the parasympathetic fibres run = dilated pupil
Medical = damages vast forum = pupil sparing
Examples of medical and surgical 3rd nerve palsy?
Medical = MS and diabetes
Surgical = Posterior communicating artery aneurysm
Signs of a 3rd nerve palsy?
Down and out pupil
Affected eye will elicit a consensual response, but will not constrict itself to direct or consensual reflex
What causes Holmes-Adie pupil?
Damage to the post-ganglionic parasympathetic fibres
These fibres allow pupillary constriction and near vision
Clinical features of Holmes-Adie pupil?
Young woman with sudden blurring vision
Dilated pupil with no response to light
Sluggish response to accommodation
What is Holmes-Adie Syndrome?
The pupil + absent knee/ankle reflexes + hypotensive
What causes Argyll-Robertson pupil?
Focal lesion in pretectal nucleus.
Clinical features of AR pupil?
Small irregular pupil
Accommodates but doesn’t react to light.
What are the different causes of Horners Syndrome?
1st order = Central lesion = MS / stroke
2nd order = pre-ganglionic = Pancoasts, apical TB, cervical rib
3rd order = post-ganglionic = Herpes zoster, carotid dissection / aneurysm
What is the cause of INO?
Lesion to the medial longitudinal fasciculus, which runs between the pons and the midbrain
Connects CN3/4/6
Clinical features of INO?
Dissociated eye movements
Impaired adduction ipsilaterally
Nystagmus contra laterally on abduction
Clinical features of CN4 lesion?
Paralysis of superior oblique = when lateral eye is up and out. When medial eye is slightly elevated
Diplopia when looking down and in e.g. going down stairs
May see abnormal head tilt
Causes of CN4 lesion?
Diabetes
Cavernous sinus thrombosis
Clinical features of CN6 lesion?
Usually abducts the eye via lateral rectus
So get esotropia and diplopia
Causes of CN6 lesion?
Long course
Tumours, trauma, CVA e.g. Millard Gubler
Wernickes
mononeuritis multiplex
What is glaucoma?
Group of disorders characterised by optic neuropathy, usually due to raised IOP
RF’s for acute glaucoma?
Hypermetropia (long sighted)
Pupillary dilation
Lens growth associated with increasing age
Clinical features of acute glaucoma?
Severe pain ± headache, N&V
Decreased acuity peripherally
Haloes around lights
Fundoscopy findings in glaucoma?
Dull hazy cornea
Optic disc cupping (cup:disc ratio >0.7)
Optic disc pallor
Bayonetting of vessels
Management of acute glaucoma?
Urgent ophthalmology referral
Pilocarpine drops = miosis to open blockage
Timolol = reduce aqueous formation
Acetazolamide 500mg IV stat = reduce aqueous formation
Follow up = laser peripheral iridotomy = hole in outer edge = fluid bypasses pupil
What is anterior uveitis?
Inflammation of the iris and ciliary body