Ophthalmology Flashcards
What is drusen?
Yellow round spots in Brusch’s membrane
Seen in age related macular degeneration
Investigations for subconjunctival haemorrhage
Check blood pressure
Bloods if recurrent/bilateral for bleeding disorder
When does a subconjunctival haemorrhage need imaging?
If can’t see whole border of haemorrhage
Central retinal artery occlusion - presentation
Sudden unilateral visual loss
Central retinal artery occlusion - cause
Thromboembolism
Arteritis (e.g. temporal arteritis)
Central retinal artery occlusion - examination findings
Afferent pupillary defect
Cherry red spot on a pale retina
What does myopia mean?
Short sighted
What does hyperopia mean?
Long sighted
Presentation of corneal abrasion
Eye pain
Photophobia
Reduced visual acquity
Foreign body sensation
Management of corneal abrasion
Topical antibiotics to prevent bacterial superinfection
Features of corneal ulcer
Eye pain Photophobia Watering foreign body sensation Focal fluorescein staining of cornea
What is the official word for squint?
Strabismus
What does strabismus mean?
Squint
How to manage squint in children?
Refer to secondary care
What is a chlazaion?
Retention cyst of meibomian gland
Chlazaion - presentation
Firm painless lump in the eyelid
Chlazaion - management
Most resolve spontaneously
Some require surgical removal
Stye - management
Hot compress and analgesia
Topical antibiotics only if associated conjunctivitis
Features of central retinal vein occlusion
Sudden, painless reduction in or loss of visual acuity
Usually unilateral
Central retinal vein occlusion on fundoscopy
Severe retinal haemorrhages
Features of scleritis
VERY painful red eye
Photophobia
Reduced visual acuity
Associated with autoimmune disease e.g. RA, SLE
Scleritis - impact of phenylephrine drops
No blanching
Episcleritis - impact of phenylephrine drops
Blanching
Scleritis - management
NSAIDS, immunosuppressants
Scleritis - complications
Perforation of the globe
Scleritis - associations
Autoimmune conditions e.g. SLE, RA
Screening for primary open angle glaucoma
Patients with a first degree relative with open angle glaucoma should be screened every year from age 40
Herpes simplex keratitis - features
Dendritic corneal ulcer on fluroescein staining
Red painful eye
Reduced visual acuity
Horner’s syndrome - features
Miosis (small pupil)
Ptosis
Enophthalmos (sunken eye)
Anhidrosis
Papilloedema - fundoscopy findings
Venous engorgement
Blurring of optic disc margin
Loss of optic cup
Papilloedema - causes
SOL
Malignant hypertension
Idiopathic intracranial HTN
Hydrocephalus
Hypercapnia
Central retinal artery occlusion - findings
Afferent pupillary defect
Cherry red spot on pale retina
Central retinal artery occlusion - causes
Thromboembolism from atherosclerosis
Arteritis e.g. temporal arteritis
What is entropion?
In turning of the eyelids
What is in turning of the eyelids called?
Entropion
What is ectropion?
Out turning of the eyelis
What is out turning of the eyelids called?
Ectropion
Foreign body in the eye - indications to refer
Suspected penetrating eye injury
Significant trauma
Chemical injury
Foreign body of organic material
Foreign body in/near centre of cornea
What does a gradual onset history of straight lines appearing crooked suggest?
Age related macular degeneration
Contraindication for antioxidant dietary supplements in macular degeneration?
Smoking
Causes of tunnel vision
Papilloedema
Glaucoma
Retinitis pigmentosa
Choroidoretinitis
Optic atrophy secondary to tabes dorsalis
Hysteria
Types of stye
Hordeloum externum
Hordeloum internum
How do patients get certified as blind or partially sighted?
Consultant ophthalmologist completes certificate of vision impairment
Criteria for severely sight impaired
VA < 3/60
VA <6/60 with reduction in field of vision
VA over 6/60 with very reduced field of vision
Criteria for sight impaired
VA 6/60
VA up to 6/24 with reduced field of vision
VA of 6/18 or better but missing lots of field of vision
Holmes-Adie pupil - features
Dilated pupil
Once pupil constricted it remains small for a long time
Slowly reactive to accommodation but very poorly to light
Absent ankle/knee reflexes
Unilateral in 80%
Additional finding in congenital horner’s syndrome
Heterochromia (difference in iris colour)
Ocular manifestations of RA
Keratoconjunctivitis sicca
Episcleritis
Scleritis
Corneal ulceration
Keratitis
What is keratoconjunctivitis sicca?
Dry eyes
Argyll-Robertson pupil features
Small irregular pupils
No response to light but able to accommodate
Argyll-Robertson pupil causes
Diabetes mellitus
Syphilis
What does mydriasis mean?
Large pupil
Causes of mydriasis/large pupil
Third nerve palsy
Homes-Adie pupil
Traumatic irdoplegia
Phaeochromocytoma
Congenital
School exclusion in conjunctivitis
No exclusion
What does miosis mean?
Small pupil
Causes of relative afferent pupillary defect
Retinal detachment
Optic neuritis
Treatment of amaurosis fugax
As TIA - 300mg aspirin
Vitreous haemorrhage - features
Sudden or subacute visual loss
Dark spots
Floaters
Vitreous haemorrhage - causes
Diabetes
Bleeding disorders
Anticoagulants
Ocular trauma
Retinal detachment - features
Dark spots, floaters
Dense shadow starts peripherally then over central vision
Veil/curtain over vision
Straight lines appear curved
Posterior vitreous detachment - features
Flashes of light in peripheral field
Floaters
Features of acute angle closure glaucoma
Severe pain Reduced visual acuity Haloes Semi-dilated pupil Cloudy cornea
Features of anterior uveitis
Pain
Blurred vision
Photophobia
Pupil small, fixed and irregular
Red eye
Ciliary flush (ring of red spreading out)
Which condition should a small, fixed, irregular shaped pupil and red eye make you think of?
Anterior uveitis
Endophthalmitis features
After intraocular surgery
Red eye, pain, visual loss
Management of anterior uveitis
Cycloplegics - atropine, cyclopentolate
Steroid eye drops
Associations with anterior uveitis
HLA B27
- Ankylosing spondylitis
- IBD
- Reactive arthritis
- Sarcoidosis
Main cause of keratitis in non-contact lense wearers
Staphylococcus aureus
Main cause of keratitis in contact lense wearers
Pseudomonas aeruginosa
Keratitis - features
Red eye and pain
Photophobia
Foreign body/gritty sensation
Hypopyon
Keratitis - management
Stop using contacts
Topical antibiotics
Cycloplegic for pain relief
Examples of cycloplegics
Atropine
Cyclopentolate
Age related macular degeneration - risk factors
Age
Smoking
Female
FHx
HTN
Dyslipidaemia
Diabetes
Age related macular degeneration - features
Reduced visual acuity
Difficult dark adaptation
Glare around objects
Flickering/flashing lights
Straight lines appear curved
Age related macular degeneration - Classification
1) Dry (90%) now called EARLY
2) Wet now called LATE
Age related macular degeneration - features of dry/early ARMD
Atrophic
Non-exudative
Drusen
Age related macular degeneration - features of wet/late ARMD
Exudative
Choroidal neovascularisation
Which type of age related macular degeneration has the worse prognosis?
Wet/late
Management of DRY age related macular degeneration
Antioxidants
Management of WET age related macular degeneration
Anti-VEGF (vascular endothelial growth factor)
Primary open angle glaucoma - risk factors
Age
Family history
Black ethnicity
Myopia
HTN
Diabetes
Steroids
Primary open angle glaucoma - features
Insidious onset found at routine appointment
Peripheral visual field loss progressing to tunnel vision
Reduced visual acuity
Primary open angle glaucoma - fundoscopy findings
Optic disc cupping
Optic disc pallor
Bayonetting of vessels
Cup notching
Primary open angle glaucoma - first line management
Latanoprost
A prostaglandin analogue
How does lantanoprost work?
Increases uveosleral outflow
Side effects of lantanoprost
Brown pigmentation of iris
Periocular pigmentation
Increased eye lash length
Primary open angle glaucoma - second line options
Timolol
Dorzolamide
Brimonidine
Pilocarpine
What type of drug is timolol?
Beta blocker
Contraindications for timolol
Asthma
Heart block
How does timolol work?
Reduces aqueous production
What type of drug is dorzolamide?
Carbonic anhydrate inhibitor
Side effects of dorzolamide
Sulphur like reactions e.g. anaphylaxis
How does dorzolamide work?
Reduces aqueous production
What type of drug is brimonidine?
Sympathomimetics
What medication contraindications starting brimonidine?
MAOI
Tricyclics
How does brimonidine work?
Reduces aqueous production AND increases outflow
What type of drug is pilocarpine?
Muscarinic receptor agonist
Side effects of pilocarpine
Constricted pupil
Headache
Blurred vision
How does pilocarpine work?
Increased uveoscleral outflow
Primary open angle glaucoma - management in advanced disease
Surgery or laser therapy
What is dacryocystitis?
Infection of lacrimal sac
Dacryocystitis - features
Watering eye
Swelling and erythema at inner canthus
Dacryocystitis - management
Oral antibiotic
Congenital lacrimal duct obstruction - features
Watering eye
May have secondary infection
Congenital lacrimal duct obstruction - management
99% resolve spontaneously by age 1 year
Teach lacrimal duct massage
Retinitis pigmentosa - features
Night blindness
Tunnel vision
Retinitis pigmentosa - fundoscopy
Black bone spindles
Optic neuritis - causes
MS
Diabetes
Syphilis
Optic neuritis - likelihood of MS
If >3 white matter lesions on MRI then 50% of MS in 5 years
Optic neuritis - management
High dose steroids
Recovery takes 4-6 weeks
Optic neuritis - features
Eye pain, worse on movement
Unilateral decrease in visual acuity
Poor colour discrimination ‘red desaturation’
Relative afferent pupillary defect
Diabetic retinopathy - risk factors
Length of diabetes Glycaemic control HTN Renal disease Pregnancy can cause rapid progression
Mild non-proliferative diabetic retinopathy
≥ 1 microaneurysm
Moderate non-proliferative diabetic retinopathy
Microaneurysms
Blot haemorrhages
Hard exudates
Cotton wool spots
Venous beading
Severe non-proliferative diabetic retinopathy
Blot haemorrhage and microaneurysms in 4 quadrants
Venous beading in 2 quadrants
Intraretinal microvascular abnormalities in 1 quadrant
Proliferative diabetic retinopathy
Neovascularisation
Diabetic retinopathy - maculopathy classification
Based on location not severity
Hard exudates and other changes on macular
Diabetic retinopathy - management
Control: blood sugar, BP, lipids
Stop smoking
Laser treatment
Intravitreal steroids
Acute angle closure glaucoma - predisposing factors
Hypermetropia (long sighted)
Pupil dilation
Lens growth associated with age
Acute angle closure glaucoma - drug causes
Anticholingerics
Tricyclic antidepressants e.g. amitriptyline
Acute angle closure glaucoma - features
Severe pain Reduced visual acuity Hard, red eye Halos Semi-dilated non-reactive pupil Dull/hazy cornea Systemic features
Acute angle closure glaucoma - immediate emergency management
IV acetazolamide
Topical pilocarpine
Topical timolol
Acute angle closure glaucoma - definitive management
Laser peripheral iridotomy
Herpes zoster ophthalmicus - features
Vesicular rash around eye
Herpes zoster ophthalmicus - what suggests ocular involvement?
Rash on tip or side of nose
This is called Hutchinson’s sign
Herpes zoster ophthalmicus - management
Oral antivirals for 7-10 days
IV antivirals in severe disease or immunocompromised
Cataracts - features
Reduced vision
Faded colour vision
Glare
Halos
Cataracts - examination findings
Defect in red reflex
Cataracts - management
Conservative: stronger glasses, bright lighting
Definitive: surgical replacement of lens with an artificial one
Cataracts - complications after surgery
Posterior capsule opacification
Retinal detachment
Posterior capsule rupture
Endophthalmitis
Cataracts - causes
Normal ageing Smoking Alcohol Diabetes Long term steroids Radiation exposure Myotonic dystrophy Hypocalcaemia Down's syndrome Uveitis
Blepharitis - causes
Meibomian gland dysfunction
Seborrhoeic dermatitis
Staphylococcal infection
Rosacea
Blepharitis - features
Bilateral
Grittiness around eyelid margin
Eyes sticky in morning
Blepharitis - management
Twice daily soft compress
Lid hygiene
Artificial tears
Blepharitis - when to refer urgently
Symptoms of corneal disease - pain, blurred vision
Sudden onset visual loss
Acutely red and painful eye
DVLA - visual field defects
Stop driving until can confirm meet national guidelines for visual fields
DVLA - monocular vision
Notify DVLA
May drive if acuity and visual field is normal in the remaining eye
DVLA - blepharospasm
Consultant opinion required