Ophthalmology Flashcards
Risk factors of chronic open angle glaucoma
Raised IOP
HTN
DM
Corticosteroids
Myopia
Afro-Caribbean
Increasing age
Genetics
Clinical findings of glaucoma on examination
Nb. chronic will be diagnosed on screening (no sx)
Pale optic disc (atrophy)
Optic disc cupping (>0.7)
Retinal vein bayonetting / kinking
Variable corneal thickness
Peripheral visual field loss
^ IOP on Goldmann applanation tonometry
Surgical management of chronic open angle glaucoma
360 selective laser trabeculoplasty (SLT)
Nb. = first line
Medical management of chronic open angle glaucoma
Medical management = second line
Prostaglandin analogues (latanoprost)
Beta blockers (timolol)
Carbonic anhydrase inhibitors (Acetazolamide / Dorzolamide)
Sympathomimetics (brimonidine)
Miotics (pilocarpine)
MOA of latanoprost (glaucoma)
Prostaglandin analogue > ^ uveoscleral outflow
SEs of latanoprost
Excessive eyelash growth
Brown pigmentation of iris
MOA of timolol (glaucoma)
Beta blocker > v aqueous production
SEs of timolol (glaucoma)
! with pt with asthma / heart block
MOA of dorzolamide
Carbonic anhydrase inhibitor > v aqueous production
SEs of dorzolamide
Blistering rash
Anaphylaxis
MOA of brimonidine
Sympathomimetic > v aqueous production & ^ uveoscleral outflow
SEs of brimonidine
Hyperaemia
MOA of pilocarpine
Miotic > ^ uveoscleral outflow
SEs pilocarpine
Blurred vision
Headaches