Ophthalmology Flashcards

1
Q

Risk factors of chronic open angle glaucoma

A

Raised IOP
HTN
DM
Corticosteroids
Myopia
Afro-Caribbean
Increasing age
Genetics

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2
Q

Clinical findings of glaucoma on examination

A

Nb. chronic will be diagnosed on screening (no sx)
Pale optic disc (atrophy)
Optic disc cupping (>0.7)
Retinal vein bayonetting / kinking
Variable corneal thickness
Peripheral visual field loss
^ IOP on Goldmann applanation tonometry

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3
Q

Surgical management of chronic open angle glaucoma

A

360 selective laser trabeculoplasty (SLT)
Nb. = first line

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4
Q

Medical management of chronic open angle glaucoma

A

Medical management = second line
Prostaglandin analogues (latanoprost)
Beta blockers (timolol)
Carbonic anhydrase inhibitors (Acetazolamide / Dorzolamide)
Sympathomimetics (brimonidine)
Miotics (pilocarpine)

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5
Q

MOA of latanoprost (glaucoma)

A

Prostaglandin analogue > ^ uveoscleral outflow

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6
Q

SEs of latanoprost

A

Excessive eyelash growth
Brown pigmentation of iris

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7
Q

MOA of timolol (glaucoma)

A

Beta blocker > v aqueous production

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8
Q

SEs of timolol (glaucoma)

A

! with pt with asthma / heart block

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9
Q

MOA of dorzolamide

A

Carbonic anhydrase inhibitor > v aqueous production

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10
Q

SEs of dorzolamide

A

Blistering rash
Anaphylaxis

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11
Q

MOA of brimonidine

A

Sympathomimetic > v aqueous production & ^ uveoscleral outflow

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12
Q

SEs of brimonidine

A

Hyperaemia

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13
Q

MOA of pilocarpine

A

Miotic > ^ uveoscleral outflow

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14
Q

SEs pilocarpine

A

Blurred vision
Headaches

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