Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharma PLE | Des > Ophtha / Protozoa > Flashcards

Ophtha / Protozoa Flashcards

1
Q

Causes hematotoxicity (megaloblastic anemia, thrombocyptopenia)

A

Sulfadiazine-pyrimethamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

This immobilizes microfilariae and alters their surface structure

A

Diethylcarbamazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

It inhibits trypanothione reductase

A

Nifurtimox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DOC: ascariasis, hookworm, pinworm, hydatid dse

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

This drug may cause Mazotti reaction when used for onchocerciasis

A

Diethylcarbamazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Antiprotozoal that inhibits chon synthesis

Blocks ribosomal movement along messenger RNA

A

Emetine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Anti-malaria

MOA: impairs progeny of malarial apicoplast genes, resulting in abnormal cell division

A

Doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DOC for malaria in pregnant patients

A

Quinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Antimalaria that causes methemoglobinemia

A

Primaquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Uncomplicated Chloroquine-resistant P. Falciparum

A

Artemether + Lumefantrine (CoArtem)

Malarone or Mefloquine or Quinine Sulfate + Clindamycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

DOC: Balantidium Coli

A

Tetracycline

Metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Antihelminthic

MOA: selectively inhibits microtubule synthesis and glucose uptake in nematodes. Inhibits fumarate reductase

A

Thiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antihelminthic

MOA: Selectively inhibits microtubule synthesis and glucose uptake in nematodes

A

Mebendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DOC for Trichinosis

A

Thiabendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Decreases secretion of aqueous humor from ciliary epithelium

A

Timolol - B blocker
Mannitol - osmotic agent
Apraclonidine - a2 agonist
Acetazolamide, Dorzolamide - carbonic anhydrase inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Drug of choice for cryptosporidiosis

A

Nitazoxanide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Avoid ethanol consumption for 48H upon drug administration

A

Niclosamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Antiprotozoal causes Agranulocytosis

A

Suramin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Used for African sleeping sickness

A

Pentamidine

Suramin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

DOC: Isospora belli

A

TMP-SMX

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

DOC: Microsporidia

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Antiprotozoal

MOA: reactive reduction by ferredoxin forming free radicals that disrupt electron transport chain

A

Nitazoxanide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

DOC for Toxoplasmosis

A

Sulfadiazine-Pyrimethamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Antihelminthic

Inhibits microtubule assembly

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Antiprotozoal that causes cardiotoxicity (T wave changes, QT prolongation)

A

Na Stibogluconate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Drug of choice for pneumocystosis

A

Co-trimoxazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

DOC for african sleeping sickness

A

Melarsoprol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Severe or Complicated P. Falciparum

A

Artesunate then Doxycycline or Clindamycin or CoArtem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Malaria chemoprophylaxis

For multidrug-resistant areas

A

Doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Antihelmithic

That should not be given to pts with cirrhosis

A

Albendazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Causes metallic taste, leukopenia and disulfiram reaction

A

Metronidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Malaria chemoprophylaxis

For chloroquine sensitive areas

A

Chloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Antiprotoxal, antibiotic

MOA: reactive reduction by ferredoxin forming free radicals that disrupt electron transport chain

A

Metronidazole

34
Q

DOC for Chagas disease

A

Nifurtimox

35
Q

Antimalaria

MOA: sequential blockade of folic acid synthesis

A

Sulfadoxine-pyrimethamine

36
Q

Antimalaria that causes cardiac conduction defects

A

Mefloquine

37
Q

DOC for severe intestinal and extraintestinal amebiasis

A

metronidazole

38
Q

DOC for trematodes: schistosomaa, paragonimus, clorchis, opistorchis, fasciolopsis, heterophyes
Cestodes: taenia, diphyllobotrhium, hymenolepsis

A

Praziquantel

39
Q

Antihelminthic
MOA: stimulates nicotinic receptors at NMJ of nematodes
Causes depolarization-induced paralysis

A

Pyrantel Pamoate

40
Q

Antihelminthic that is contraindicated in children <5 yo and pregnant pt

A

Ivermectin

41
Q

Causes pseudomembranous colitis

A

Clindamycin

42
Q

DOC: Toxoplasma Gondii

A

Pyrimethamine + Clindamycin + Folinic acid or Spiramycin

43
Q

Antihelminthic that is contraindicated in pts with hepatic dysfunction

A

Pyrantel Pamoate

44
Q

Antimalarial that causes cardiotoxicity (prolongs PR and QT interval)

A

Halofantrine

45
Q

DOC: Trypanosoma Cruzi

A

Nifurtimox

Benznidazole

46
Q

Tx of Glaucoma

MOA: increased outflow via uveoscleral veins

A

Epinephrine - nonselective a-agonists

47
Q

DOC for ascaris, hookworm pinworm infections

A

Pyrantel Pamoate

48
Q

Antihelminthic

MOA: intensifies GABA-mediated neurotransmission in nematodes. Immobilizes parasites

A

Ivermectin

49
Q

DOC for Leishmaniasis

A

Sodium Stibogluconate

50
Q

DOC: Pneumocystic jivoreci

A

TMP-SMX

51
Q

Drug of choice for asymptomatic cyst carrier of E. Hystolytica

A

Diloxanide furoate

52
Q

DOC for Filariasis and eye worm disease

A

Diethylcarbamazine

53
Q

DOC for uncomplicated falciparum malaria in PH

A

Artemisinin

54
Q

Malaria chemoprophylaxis

For chloroquine resistant areas

A

Mefloquine

Malarone

55
Q

Anithelminthic that is contraindicated in pregnancy

A

Thiabendazole

56
Q

DOC for babesia

A

Clindamycin

Quinine

57
Q

Flow of Aqeuos Humor

A

Ciliary body - posterior chamber - anterior chamber angle - pupil - anterior chamber - trabecular meshwork - canal of Schlem - uveoscleral veins

58
Q

MOA:

Sequential blockade of dihydropteroate synthase (sulfamethoxazole) and dihydrofolate reductase (trimethroprim)

A

Co-trimoxazole

Sulfadiazine-Pyrimethamine

59
Q

This drug is an antimalira and a tetracycline antibiotic as well

A

Doxycycline

60
Q

Antiprotozoal drug that causes thrombocytopenia, Leukopenia, Seizures

A

Eflornithine

61
Q

Causes Mazzotti reaction

A

Ivermectin

DEC

62
Q

Causes acute hemolysis in G6PD deficiency, assume cross-hypersensitivity, SJS, toxic epidermal necrolysis

A

Co-trimoxazole

63
Q

Antiprotozal, aminoglycoside
MOA: inhibits protein synthesis
Binds to 16S ribosomal subunit
Luminal amebicide

A

Paromomycin

64
Q

Tx for glaucoma

MOA: ciliary muscle contraction opening of trabecular meshwork, increased outflow

A

Pilocarpine, Physostigmine - cholinomimetics

65
Q

Antimalarial

MOA: forms toxic free radicals in malarial food vacuole

A

Artemisinin

66
Q

Anithelminthic that causes agranulocytosis

A

Mebendazole

67
Q

Antimalaria drug
MOA:
______ disrupts mitochondrial electron transport
______ inhibits folate synthesis

A

Atovaquone-

Proguanil

68
Q

This drug should not be taken with milk because it will decrease the absorption

A

Doxycycline

69
Q

DOC for whipworm infections

A

Mebendazole

70
Q

Antihelminthic that increases membrane permeabilty to calcium leading to paralysis, vacuolization and death

A

Praziquantel

71
Q

Malaria chemoprophylaxis

For P. Vivax and P. Ovale

A

Primaquine

72
Q

Used to treat Advanced West African Sleeping Sickness (DOC)

A

Eflornithine

73
Q

Antimalaria

MOA: forms electron-transferring redox compounds that act as cellular oxidants

A

Primaquine

74
Q

P. Vivax and P. Ovale

A

Chloroquine then primaquine

75
Q

This antimalaria drug causes folic acid deficiency

A

Pyrimethamine

76
Q

MOA: complexes with DNA to prevent strand separation

Blocks DNA replication and transcription

A

Quinine

77
Q

DOC: Cryptosporidium

A

Paromycin

Azithromycin

78
Q

Chloroquine-sensitive P. Falciparum

A

Chloroquine

79
Q

An antimaliarial drug that is also used for DMARDs - disease modifying anti-rheumatic drug

MOA:prevents polymerization of heme into Hemozoin

A

Chloroquine

80
Q

Anti-malarial drug that causes Cinchonism (headache, tinnitus, vertigo)

A

Quinine

81
Q

DOC for strongyloidiasis

A

Ivermectin

82
Q

Antihelminthic

MOA: uncouples oxidative phosphorylation or by acting ATPases

A

Niclosamide

Pharma PLE | Des (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions