Online Med Ed Wrongs Flashcards
Barretts esophagus histologically changes from normal tissue of the esophagus to tissue in the duodenum. What tissue will be seen histologically?
columnar epithelium
What are the “alarm” sx of GERD?
weight loss, emesis, dysphagia
What test do you skip to if the patient presents with alarm sx?
EGD
What is the treatment for someone with long time GERD and Barretts that has ANY amount of dysplasia?
Endoscopic destruction of the lesion
Which type of antihypertensive drugs can cause hypokalemia?
thiazide diuretics (and loop)
What type of anticoagulation do you use to prevent stroke in someone with AFIB?
warfarin
What are you wanting to increase in someone with right sided infarct? (II, V, avF)?
preload (give IV fluids)
Which drugs cause hypokalemia (and can be useful in patients with hyperkalemia)?
- beta agonists (albuterol)
- increases K+ uptake by cells
- Insulin
- enhances Na/K/ATPase pump with glucose
- loop diuretics (furosemide)
- inhibits Na/K/Cl pump in Loop of Henle
- intestinal cation exchange resins
- alkalinaizing agents (sodium bicarbonate)
- increases serum pH causing potassium, shift into cells
What is the most common cause of secondary nephrotic syndrome?
DM
What is the most likely complication of nephrotic syndrome?
venous thrombosis
(due to hypercoagulable state)
Why do you get edema with nephrotic syndrome?
proteins (albumin) are lost in the urine and the oncotic pressure is decreased in the CV system–>edema
How is nephrotic syndrome defined?
>3.5 grams collected in a 24 hour urine protein collection
What are 5 complications of nephrotic syndrome?
- protein malnutrition
- hypovolemia
- acute kidney injury
- infection
- thromboembolism
Unilateral, complete hemi-facial paralysis (including forehead muscles) is due to what?
peripheral facial nerve palsy: characterized by dysfunction of the lower motor neuron of CN VII
Unilateral paralysis in the lower face (can still wrinkle forehead) is caused by what?
central facial nerve palsy: characterized by dysfunction of the upper motor neuron of CN VII (at a level in the brain above the pons)
What are the signs of peritonsilar abscess?
trismus (inability to open mouth), dysphagia, ear pain, fever, red, enlarged, medially displaced tonsil with uvular deviation away from the affected side
What is pemphigoid gestationis?
pregnancy-associated auto-immune disease; pruritis with papules and plaques which progress to become vessicles and bullae
What will a biopsy positive for pemphigoid gestationis show?
subepidermal bliasteing with eosinophil predominant infiltrate at the dermal-epidermal junction.
Direct immunofluorescence is positive for deposition of C3 and/or IgG along the basement membrane.
“salt split” technique shows deposition along the floor of the lesion
What does a positive “salt split” technique for a bullous pemphigoid show?
deposition along the roof of the blister
What is the treatment of corneal abraision in non-contact wearers?
polymyxin B/trimethoprim eye drops
What is the treatment of corneal abraision in contact wearers?
fluoroquinolones (ciprofloxacin) or aminoglycosides
What are the screening tests for dysplasia of the hip?
Barlow=hip flexed 90 degrees, and b/l hips adducted with posterior pressure directed at the knee
Ortolani=hip flexed at 90 degrees and b/l hips abducted and push forward on the head of the femur to push back into acetabulum
+ test=clunking sensation felt
Next step in a infant with both + Barlow and Ortolani tests?
refer to ortho
Next step in infant with - Bartlow and + Ortlani?
ortho
Next step in infant with + Bartlow only?
monitor/observe patient and repeat exam at a later date
Child with new onset, conductive hearing loss with intact TM with invaginaitons, granulation tissue, and small white mass beyond TM would indicate what?
cholesteatoma
What are the sx of avascular necrosis?
groin pain that is worse with bearing weight
What are risk factors for avascular nevrosis?
chronic use of corticosteroids and heavy alcohol use
What is senn on imaging in avascular necrosis?
“crescent sign”; a subchondral crescent-shaped radiolucent area representing an area of necrotic bone.
Who is at risk for avascular necrosis?
sickle cell, femoral neck fx, SLE, smokers
how does an anal fissure present?
sharp tearing pain with bloody bowel movements
Pt presents with b/l leg pain, aching, cramping that is worse with exertion and is relieved by rest. Dx?
intermittent claudication (angina of the legs)
*eitiology linked to peripheral artery disease and secondary atherosclerosis
what is minimal change disease?
the most common cause of nephrotic syndrome in children less than 10, gets better with corticosteroids
painless , gross/frank hematuria in males 10-20 within days of a viral infection (URI) or pharyngitis and HTN (no edema)?
IgA nephropathy
hematuria with RBC casts, edema, and HTN, associated with group A strep or URI weeks prior?
post strep/infectious glomerulonephritis
unexplained hyperthyroidism?
struma ovarii; look for elevated levothyroxine (T4)
Why are people with crohns more likely to get calcium oxalate kidney stones?
decreased intestinal absorption of bile salts and fatty acids
Pts with PCOS have increased risk for what type of cancer?
endometrial
name important P450 inhibitors:
erythromycin, cimetidine, ketoconazole, itraconozole
What additional vaccine are children with sickle cell supposed to get at 2 years old?
23-valent pneumococcal polysaccharide vaccine (PPSV-23)
neonatal foot deformity: midline deviation of all metatarsal bones
metatarsus adductus
neonatal foot deformity: “up and out” appearance of the foot/feet
calcaneovalgus
neonatal foot deformity: “rocker bottom feet”
congenital vertical talus; “reversed arch”