Oncology Pharm (anti-emetics) Flashcards
1
Q
what is the MOA for Gravol (diminhydrinate)
A
anticholinergic
2
Q
what are uses for Gravol
A
mild N+V
3
Q
what are AEs of Gravol
A
DROWSINESS, dizziness, blurred vision, dry mouth, paranoia, agitation, HTN
4
Q
what are cautions with Gravol?
A
potential for abuse, watch for drowsiness/dizziness in older adults
5
Q
What is the MOA for Zofran?
A
serotonin antagonist
6
Q
what are uses for Zofran
A
high emetogenic agents (N+V)
7
Q
what are AEs of Zofran
A
constipation, prolonged QTc
8
Q
what are cautions when using Zofran
A
may cause severe constipation, consider stool softeners
can cause dysrhythmias in people with long QT syndrome
9
Q
When should anti-emetic therapy be started in regards to chemo infusion
A
start before - better at prevention than suppression
