oncology part 1 Flashcards
phase 1 of investigation drug trials
maximum dose acceptable
phase 2 of investigation drug trials
response to dose ; how s body reacting
phase 3 of investigation drug trials
narrow the effectiveness of routes down
things that point to cancer
mass and swellings pale loss of energy frequent bruising persistent pain eye problems that are sudden illnesses that don't go away or keeps getting sick rapid weight loss
when is cancer found in kids
they go in for something unrelated and something gets pick up
leukemia
Unrestricted proliferation of immature WBCS that take up all the resources and can’t make rbc, platelets leading to risk of anemia, infection risk , more bruises & bleeding
Acute lymphoblastic leukemia
Age?
Most common cancer in children
3-5 years old
Acute Myelongenous Leukemia
age?
Who is at risk?
Peaks in adolescent age
Genetic disorders like down syndrome are at risk
Main focused treatments of leukemia
Bone marrow dysfunction
Hyper-metabolic state
CNS
Reiculoendothelial
CNS
increased IOP
cranial nerves involvement
Reiculoendothelial effects
Hepatic and spleen enlargement
lymph node enlarges
How many types of Biotherapy for cancer are there?
List them
3 main types-
Immunotherapy or biologic response modification
Antibodies or segments of genes to target cancer
Targeted therapies
Immunotherapy or biologic response modification Biotherapy
Stimulate immune system to act against the cancer cells itself
Antibodies or segments Biotherapy
Use of genes to target those cancer cells
Targeted therapies Biotherapy
Interfere with specific molecules involved in tumor growth
