Oncology Flashcards
Cancer definition (5 categories)
- rapid cell production
- uncontrolled cell growth
- involves any body tissue
- does not go through apoptosis
- ability to metastasize
Metastasis is
invasive, increased tumor growth
What are the 3 stages of cancer development
- Initiation
- Promotion
- Progression
What is the initiation phase?
The phase in which the cancer is stimulated.
What are the causes of cancer (6)
- Viruses
- Hormones
- Radiation
- Chemicals
- Genetics factors
- Unk factors
What is the promotion phase of cancer?
Cells abnormally dividing
What is the progression phase of cancer?
Evidence of metastasis
Tumors are classified by the
- site
- grade
- stage
Clinical staging classifications 0-4
0: Cancer in site; tumor has not gone anywhere and is less than 3mm
1: tumor still tiny and barely grown
2: Limited local spread; mild growth
3: Extensive local and regional spread; ex- started in tonsil and is now in esophagus
4: Another organ is involved
Cancer is diagnosed by
- symptoms
- Dx tests
- Pathology
Hormonal receptor cancer
hormones drive the cancer; meds are usually given to stop the hormone growth
Dx test; carcinoembryonic antigen (CEA)
blood test; helps evaluate if cancer is improving or worsening
Alph-fetoprotein test assesses
malignant liver cells
genetic testing assesses
if the patient has a known genetic mutation
Cancer prevention (5)
- Avoid/reduce exposure
- Eat a balanced diet
- Exercise regularly
- Rest
- regular exams
7 warning signs of cancer
C: change in bowel/bladder habits A: a sore throat that doesnt heal U: unusual bleeding/discharge from any orifice T: thickening of skin or a lump I: indigestion or difficulty swallowing O: obvious change in a wart or mole N: nagging cough/hoarseness
Treatment goals
- cure
- control rate
- pain
Cancer Tx methods (5)
- surgery
- radiation
- chemo
- hormonal therapy
- bio therapies (only targets cancer specific cells)
chemotherapy is a ____ therapy
systemic
Chemo can be administered
IV, PO, IM, SQ, topical
chemo is most effective in tumors with
long cell cycles
chemotherapy can slow
cancer
chemo is most effective in _____ _____ tumors
slow growing
chemotherapy complication- vesicant due to extravasation
IV chemo does not go into vein but around the vein and kills/blister surrounding tissues