Oncology Flashcards

1
Q

AFP

A

Liver cancers and germ cell

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2
Q

b-hCG

A

Choriacarcinoma

Germ cell

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3
Q

BRCA1 and 2

A

Ovarian cancer

Breast cancer

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4
Q

BCR-ABL and alternative name

A

CML!!, AML, ALL

Philidelphia chromosome

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5
Q

CA15

A

Breast cancer

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6
Q

CA19

A

Pancreatic, gallbladder, bile duct, gastric

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7
Q

CA125

A

Ovarian

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8
Q

Calcitonin

A

Medullary thyroid

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9
Q

CEA

A

Colorectal

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10
Q

CD20

A

NHL

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11
Q

EGFR mutation analysis

A

NSCLC

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12
Q

Oestrogen/Progesterone receptor

A

Breast

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13
Q

Fibrin/fibrinogen

A

Bladder

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14
Q

HE4

A

Ovarian

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15
Q

HER2

A

Breast
Gastric
GO junction adenocarcinoma

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16
Q

Immunoglobulins

A

MM

17
Q

KRAS mutation analysis

A

Colorectal

NSCLC

18
Q

LDH

A
Lymphoma
Leukaemia
Melanoma
Germ cell
Neuroblastoma
19
Q

PSA

A

Prostate

20
Q

Thyroglobulin

A

Thyroid

21
Q

Philadelphia chromosome

A

t9:22, which results in fusion gene BCR-ABL

22
Q

Rituximab

A

Anti-CD20 monoclonal antibody, B-cell lymphoma

23
Q

Trastuzumab alternative name and use

A

Herceptin, monoclonal antibody that prevents her2 function, biologic used in Breast Ca

24
Q

Tamoxifen

A

Hormonal anti-oestrogen used in oestrogen receptor positive breast cancer

25
Q

Two main immunotherapy drugs

A

Interferon

Interleukin

26
Q

Two main delivery modes in radiotherapy

A

Teletherapy

Bracytherapy

27
Q

3 preferred opioids in CKD

A

Fentanyl
Buprenorphine
Alfentanil

28
Q

Chemo drug lung fibrosis is most serious side effect

A

Bleomycin

29
Q

Two chemo drugs often cause peripheral neuropathy

A

Vincristine

Cisplatin

30
Q

Chemo drug haemorrhagic cystitis

A

Cyclophosphamide

31
Q

Earliest and most common syx of MSCC

A

Back pain

32
Q

What is a PET scan measuring

A

Glucose uptake

33
Q

Chemo drug cardiomyopathy

A

Doxyrubacin

34
Q

5 key bony mets

A
Breast
Bronchus
Thyroid
Kidney
Prostate
35
Q

4 tumours which commonly metastasise to lung FIRST

A

Breast
Bronchus
Thyroid
Kidney