Oncology

Question 1

Type of drug, use, and side effect of doxorubicin

Answer 1

Anthracycline, lymphoma, and cardiomyopathy

Question 2

Give an example of an alkylating agent and its side effects

Answer 2

Cyclophosphamide - haemorrhagic cystitis, myelosuppression, transitional cell carcinoma

Question 3

Side effects of vincristine

Answer 3

Peripheral neuropathy, paralytic ileus

Question 4

Side effects of cisplatin

Answer 4

Ototoxic, peripheral neuropathy, hypomagnesaemia

Question 5

Which thyroid tumour secretes calcitonin and from which cells do these tumours arise?

Answer 5

MEDULLARY CA and parafollicular cells

Question 6

What are the signs of bone mets?

Answer 6

Pain, pathological fractures, hyperglycaemia, and raised ALP

Question 7

First and second line for chemo induced nausea and Vomiting

Answer 7

1st - domperidone

2nd - ondansetron or metoclopramide +/- dexamethasone

Question 8

What type of drugs are metoclopramide and ondansetron?

Answer 8

5-HT3 antagonist