Oncological Screening Flashcards
what is similar ab the number 1 type of cancer in men and women
both are areas that are very affected by hormones
men - prostate
women - breast
how do the most prevalent types of cancer compare between women and men
most common 2-5 are the same
2. lung and bronchus
3. colon and rectum
4. urinary bladder / uterine corpus
5. melanoma of skin
what type of cancer has the highest mortality rate
lung and bronchus
what are the 3 basic rules of cancer screening
- review PMH
- clinical presentation
- associated s/sx
what are 4 components of a risk factor assessment
age >50yo
ethnicity
family hx
environmental and lifestyle
what age range has the highest incidence of cancer and cancer mortalities
> 65yo
what 4 types of cancer have inc incidence in older adults
colon/rectum
ovarian
prostate
chronic leukemia
what 2 types of cancer have inc incidence in a younger population
testicular
breast
what are 3 known childhood cancers
acute leukemia
retinoblastoma
sarcoma
what ethnicity has an inc risk? describe what that risk entails
African Americans
10x greater incidence than white
30% higher mortality
less responsive to cancer tx
how does a hispanic ethnicity impact the risk
lower incidence of the more common cancers
inc incidence of cancers w infectious etiology
- stomach
- liver
- uterine
- cervical
- gallbladder
how do you do a screen for a family hx
connected to 1st gen family members
- immediate family
what cancers is a family hx important bc of their mutated gene etiology
breast
colon
ovarian
how does a family hx of cancer impact the screening process
colonoscopy and mammograms screenings start at 50yo
- if known family hx, will come in to start screening 10yr prior to when family member was dx
what are 5 risks for hereditary cancer syndrome
cancer in >2 family members
cancer in family <50yo
same type of cancer in family
different CA in 1 person in family
rare cancer in >1 family member
what are modifiable risk factors that are linked to 80-90% of cancer cases (6)
obesity
diet
sedentary lifestyle
sexual practices
tobacco/alcohol/drug use
sun exposure / tanning beds
what are occupational risk factors
ionizing radiation
agent orange
chemical agents
what cancers have low survival rates (4)
pancreatic cancer
lung/bronchus
liver and intrahepatic duct
esophageal
what are PT warning signs (3)
idiopathic prox weakness
- trendelenburg gait
- SOB
- STS and stair climbing
DTR changes
pain & night pain (intense &/or constant)
how is DTR linked to cancer
DTR related to carcinomatous meningitis
- cancer cells to meninges of brain or SC resulting in neuromyopathy
will see DTRs and prox ms weakness
what are 7 warning signs
C hanges in bowel/bladder habits
A sore doesn’t heal in 5wks
U nusual bleeding/discharge
T thickening lump in breast or other
I ndigestion or difficulty swallowing
O bvious changes in wart or mole
N agging cough or hoarseness
what are 3 general types of cancer
carcinoma (85%) - epithelial
sarcoma - connective
bloodborne - blood and lymph
what are ex of carcinomas (4)
skin
intestines
breast
lung
what are ex of sarcomas (3)
bone
cartilage
ms
what are ex of bloodborne (3)
leukemia
multiple myeloma
lymphoma
what are the most common sites for metastatic cancer (5)
integ
pulm
neuro
msk (often bones)
hepatic