Oncological pharmacology

Question 1

What are tyrosine kinase inhib?

Answer 1

Block tyrosine kinase associated w BCR-ABL defect which causes CML?

Question 2

Before starting chemo what do you need to screen?

Answer 2

Echo
PFTs
BBV

Question 3

What are some consequences of radiotherapy?

Answer 3

Fertility issues
Localised skin lesions
Other cancers
Ischaemic heart disease
(damage the organs by the places there RT is
used)
Fatigue from radiation
FIbrosis and shrinking of breast tissue
Long term skin colour changes - usually darker

Question 4

What are some general SEs of chemo?

Answer 4

Stunted growth in children
Immunodef
Neurotoxicity
Infertility
Secondary malignancy
Cardiotoxicity

Question 5

What is the main SE of TKI?

Answer 5

Dilated cardiomyopathy
Herception - heartceptin

Question 6

Draw the chemotoxicity man please

Answer 6

Answers on iPad

Question 7

How long does it take for RT to have its benefit?

Answer 7

2 weeks, can make things worse first

Question 8

What are the SEs of immunotherapy?

Answer 8

Dermatitis
Colitis
Pneumonitis