Oncogenes Flashcards

1
Q

abl

A

CML

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2
Q

c-myc

A

Burkitt’s lymphoma

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3
Q

bcl-2

A

follicular and undifferentiated lymphoma

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4
Q

HER2-neu

A

Breast, ovarian, and gastric carcinoma

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5
Q

ras

A

Colon cancer

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6
Q

most common oncogene

A

ras

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7
Q

L-myc

A

Lung tumor

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8
Q

N-myc

A

neuroblastoma

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9
Q

ret

A

MEN 2A and 2B

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10
Q

c-kit

A

Gastrointestinal stromal tumor

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11
Q

tyrosine kinases

A

abl, HER2, ret

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12
Q

Transcription factor

A

c-myc, l-myc, n-myc

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13
Q

anti-apoptotic molecule

A

bcl-2

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14
Q

GTPase

A

ras

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15
Q

cytokine receptor

A

c-kit

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16
Q

BRAF

A

melanoma