Onco: Treatment Complied Flashcards
Chemotherapy associated N and V for High risk chemotherapy regimens
Neurokinin 1 receptor antagonist +
Sertonin antagnosis (5HT3) +
Dexamethasone
Chemotherapy associated N and V with Moderate risk chemo regimens
Sertonin antagnosis (5HT3) + Dexamethasone
Chemotherapy associated N and V With low risk chemo regimens
Single agent
Neurokinin 1 receptor antagonist or
Sertonin antagnosis (5HT3) or
Dexamethasone
Mucositis
Palifermin
Kertainocyte growth factor- preventive
Diarrhea secondary to chemo
Loperamide
Octerotide- non responsive
Alopecia
Chemo caps
Acneiform rash seen with EGFR directed small molecules
Topical clindamycin gels
Low potency GCs
The ff are recommended for Hypertension secondary to anti VEGFR/VEGF except A.Lisinopril B.Amlodipine C.Clonidine D. Metoprolol
D
The rest are recommended
SVC syndrome
Primary tx: radiotherapy Relievers: Diuretics Low salt diet Head elevation O2
SVC syndrome (Only if lymphoma)
Glucocorticoids
Pericardial effusion/ tamponade
Pericardiocentesis Sclerotherapy Peridacardial window Complete pericardial stripping Cardiac irradiation Systemic chemo
Intestinal obstruction
Initial : Surgical evaluation
Self expanding metallic stents
Nasogastric decompression
Percutaneous endoscopic or surgical gastrsotomy
Urinary obstruction (associated with flank pain, sepis , or fistula)
Immediate palliative urinary diversion:
Internal ureteral stents
Percutaneous nephrostomy
Bladder outlet obstruction due to malignancy
Suprapubic cystostomy
Malignant biliary obstruction
Palliative stenting for disabling pruritus resistant to medical treatment, severe mal abosorption, infection
Malignant spinal cord compression
Dexamethasone (6 mg IV q 6hrs)
Radiation + GC
Increased intra cranial pressure- Initial management
Dexamethasone
Stereotactic radiosurgery
Increased intra cranial pressure (Multiple mets)
WBRT (Whole brain RT)
Increased ICP: Single mass
SIngle: surgical excision followed by WBRT
Increased ICP: With 1-4 lesions with stable systemic disease and have failed WBRT
Sterotactic surgery
Neoplastic meningitis
Intrathecal chemotherapy (Methotreaxate, cytarabine, thiotepa)
Seizures
Phenytoin or Levetiracetam
Prevention of TLS
Allopurinol
Urinary alkalinization
Aggressive hydration
Recombinant urate oxidase given in allopurinol failure on the background if renal failure
Rasburicase
Prevention of Human antibody infusion reaction
Diphenhydramine
Hydrocortisone
Acetaminophen
HUS
No optimal tx.
Rituximab (?)
Typhilitis
Broad spectrum antibiotic coverage
Nasogastric suction
Surgery
Hemorrhagic cystitis
MESNA
Irrigate with formalin or NAC or Prostaglandins
Hepatic candidiasis
Amphotericin B
