Onco: Treatment Complied

Question 1

Chemotherapy associated N and V for High risk chemotherapy regimens

Answer 1

Neurokinin 1 receptor antagonist +
Sertonin antagnosis (5HT3) +
Dexamethasone

Question 2

Chemotherapy associated N and V with Moderate risk chemo regimens

Answer 2

Sertonin antagnosis (5HT3) +
Dexamethasone

Question 3

Chemotherapy associated N and V With low risk chemo regimens

Answer 3

Single agent
Neurokinin 1 receptor antagonist or
Sertonin antagnosis (5HT3) or
Dexamethasone

Question 4

Mucositis

Answer 4

Palifermin

Kertainocyte growth factor- preventive

Question 5

Diarrhea secondary to chemo

Answer 5

Loperamide

Octerotide- non responsive

Question 6

Alopecia

Answer 6

Chemo caps

Question 7

Acneiform rash seen with EGFR directed small molecules

Answer 7

Topical clindamycin gels

Low potency GCs

Question 8

The ff are recommended for Hypertension secondary to anti VEGFR/VEGF except
A.Lisinopril
B.Amlodipine
C.Clonidine
D. Metoprolol

Answer 8

D

The rest are recommended

Question 9

SVC syndrome

Answer 9

Primary tx: radiotherapy
Relievers:
Diuretics
Low salt diet
Head elevation
O2

Question 10

SVC syndrome (Only if lymphoma)

Answer 10

Glucocorticoids

Question 11

Pericardial effusion/ tamponade

Answer 11

Pericardiocentesis
Sclerotherapy
Peridacardial window
Complete pericardial stripping
Cardiac irradiation
Systemic chemo

Question 12

Intestinal obstruction

Answer 12

Initial : Surgical evaluation
Self expanding metallic stents
Nasogastric decompression
Percutaneous endoscopic or surgical gastrsotomy

Question 13

Urinary obstruction (associated with flank pain, sepis , or fistula)

Answer 13

Immediate palliative urinary diversion:
Internal ureteral stents
Percutaneous nephrostomy

Question 14

Bladder outlet obstruction due to malignancy

Answer 14

Suprapubic cystostomy

Question 15

Malignant biliary obstruction

Answer 15

Palliative stenting for disabling pruritus resistant to medical treatment, severe mal abosorption, infection

Question 16

Malignant spinal cord compression

Answer 16

Dexamethasone (6 mg IV q 6hrs)

Radiation + GC

Question 17

Increased intra cranial pressure- Initial management

Answer 17

Dexamethasone

Stereotactic radiosurgery

Question 18

Increased intra cranial pressure (Multiple mets)

Answer 18

WBRT (Whole brain RT)

Question 19

Increased ICP: Single mass

Answer 19

SIngle: surgical excision followed by WBRT

Question 20

Increased ICP: With 1-4 lesions with stable systemic disease and have failed WBRT

Answer 20

Sterotactic surgery

Question 21

Neoplastic meningitis

Answer 21

Intrathecal chemotherapy (Methotreaxate, cytarabine, thiotepa)

Question 22

Seizures

Answer 22

Phenytoin or Levetiracetam

Question 23

Prevention of TLS

Answer 23

Allopurinol
Urinary alkalinization
Aggressive hydration

Question 24

Recombinant urate oxidase given in allopurinol failure on the background if renal failure

Answer 24

Rasburicase

Question 25

Prevention of Human antibody infusion reaction

Answer 25

Diphenhydramine
Hydrocortisone
Acetaminophen

Question 26

HUS

Answer 26

No optimal tx.

Rituximab (?)

Question 27

Typhilitis

Answer 27

Broad spectrum antibiotic coverage
Nasogastric suction
Surgery

Question 28

Hemorrhagic cystitis

Answer 28

MESNA

Irrigate with formalin or NAC or Prostaglandins

Question 29

Hepatic candidiasis

Answer 29

Amphotericin B