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on track Flashcards

1
Q

What is fidaxomicin used for ?

A

used to treat c.difficile

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2
Q

Describe most likely interaction between tricyclics and opioids?

A

sedation

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3
Q

Why Beta 2 agonists must be used with caution in patients with diabetes, especially intravenous salbutamol ?

A

Can cause ketoacidosis

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4
Q

What is interaction between statins and daptomycin ?

A

increase the risk of rhabdomyolysis

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5
Q

Which drug can cause hallucinations from the list below?

  • paracetamol
  • dantrolene
  • baclofen
  • benfroflumethiazide
  • metformin
A

BACLOFEN

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6
Q

Interaction between warfarin and cranberry juice?

A

cranberry juice is enzyme inhibitor, increase warfarin concentrations

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7
Q

Which drug from the list below can cause dyspepsia?

  • atenolol
  • bendro
  • lisinopril
  • nifedipine
  • valsartan
A

-Nifedipine
Calcium antagonists, nitrates, theophyllines, bisphosphonates, corticosteroids and nonsteroidal anti-inflammatory drugs can cause dyspepsia.

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8
Q

According to SPC can lisinopril cause hypokalaemia or hyperkalaemia ?

A

hyperkalaemia

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9
Q

When would it be the legal obligation to report female genital mutilation ?

A

“All pharmacy professionals now have a legal duty to report, orally or in writing, to the police if: they observe physical signs that female genital mutilation (FGM) may have taken place in a girl under the age of 18, or a child or young person tells them that they have had FGM.”

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10
Q

Can penicilin V be given for breastfeeding women ?

A

Penicillin V is considered compatible for breastfeeding but the infant should be monitored for adverse effects.

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11
Q

biphasic insulin aspart 30/70 is long acting or short acting ?

A

short acting

Insulin can be kept outside the fridge once opened

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12
Q

An elderly woman presents in the pharmacy on a Friday morning complaining of a bothersome headache.
Which one of the following symptom clusters require you to make an urgent referral to the doctor?
-Bilateral generalised headache
-Bilateral headache with symptoms that worsen as the day progresses
-Unilateral frontal headache which worsens on bending down
-Unilateral headache with associated nausea
-Unilateral headache with malaise

A

Unilateral headache with associated nausea suggests migraine; bilateral generalised headache and bilateral headache with symptoms that worse as the day progresses suggests tension-type headache; unilateral frontal headache which worsens on bending down suggests sinusitis; unilateral headache with malaise could be temporal arteritis.

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13
Q

What side effect can tibolone cause to breasts?

A

nipple pain

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14
Q

What is osteomyelitis and what is the treatment ?

A

flucloxacillin

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15
Q

What does MDRD stand for ?

A

modification of diet in renal disease : MDRD is used to measure. eGFR of a patient

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16
Q

Patients who had a splenectomy should have which vaccine:

  • hepatitis B
  • hepatitis A
  • pneumococcal vaccine
  • rabies vaccine
  • typhoid vaccine
A

pneumococcal vaccine because if they had a splenectomy they are at increased risk of pneumococcal infection.

17
Q

Orlistat may reduce the absorption of which vitamins ?

A

ADEK: fat soluble

18
Q

What electrolyte disturbance mirtazapine can cause ?

A

hyponatraemia

19
Q

Which ONE of the following is most likely to cause dry mouth ?

  • salbutamol
  • salmeterol
  • ipratropium
  • terbutaline
  • theophylline
A

ipratropium is antimuscarinic drug and therefore can cause dry mouth

20
Q

Mr G is a 78-year-old retired school teacher. He has arthritis and is experiencing severe discomfort in his movements.
Which one of the following allied healthcare professionals is the most suitable to assess and support Mr G with his discomfort and could provide the patient with the support aids to assist him?
-dietitian
-occupational therapist
-orthotist
-support worker

A

ORTHOTIST: provide support to correct problems or deformities in peoples nerves, muscles or bones. Examples include splints, braces and special footwear

21
Q

Clenbuterol is part of which schedule ?

A

schedule 4 part 2

22
Q

Mrs R is a patient who has AIDS. She has been diagnosed with mild pneumocystis pneumonia. She is unable to tolerate trimethoprim.Which single medication is the most likely treatment option for her pneumonia?

  • atovaquone
  • co-trimoxazole
  • hydrocortisone
  • pentamidine isetionate
  • prednisolone
A

Atovaquone is licensed for the treatment of mild to moderate pneumocystis infection in patients who cannot tolerate co-trimoxazole (co-trimoxazole is made up of sulfamethoxazole and trimethoprim - Note that Mrs R can not tolerate trimethoprim). The other options are suitable for severe pneumocystis infection.

23
Q

Mr K is a 21-year-old student who comes to your pharmacy with a new prescription for himself. You look at the prescription and advise Mr K to report immediately any sore throat, fever, infection, unexplained bleeding and bruising, purpura, mouth ulcers or rashes to their doctor.
Which of the following drugs is this counselling advice most suitable for?
-bezafibrate
-glucosamine
-loperamide
-penicillamine
-sumatriptan

A

Penicillamine has been associated with blood disorders. Therefore, patients should be counselled to report these signs immediately to their doctor, if and when they develop.

24
Q

Mrs H is a 82-year-old retired pilot. She has chronic kidney disease (CKD) with the following reported values: eGFR: 25 ml/min/1.73 m2, ACR: 17 mg/mmol.
Which one of the following drugs is LEAST suitable for use in Mrs H?
-allopurinol
-atenolol
-metformin
-paracetamol
-simvastatin

A

metformin: avoid if eGFR is less than 30 ml/min

25
Q

Which medicines can only be prescribed on FP10PCD form ?

A

this form should be used for CD 2 and 3, then original sent to NHS agency.
FP10PCD IS FOR PRIVATE PRESCRIPTION

26
Q

You are the on duty pharmacist in a community pharmacy. Miss JA, who is 17 years old, presents in your pharmacy enquiring about a rash she has developed. You note from her patient medication record that you recently dispensed amoxicillin capsules for her. She tells you that this was for tonsillitis. Her patient medication record suggests she has received amoxicillin before but she states that she has never had a rash like this before now.
What is the most suitable course of action?
-REFER TO GP FOR FURTHER INVESTIGATION
-REFER TO GP URGENTLY
-SELL LOZENGE
-SEND TO A&E

A

REFER TO GP FOR FURTHER INVESTIGATION AND TREATMENT
Miss JA’s symptoms suggest she may have glandular fever and the GP should investigate this further. Patients with glandular fever may experience a rash when given amoxicillin.

27
Q

How long until DMARD start to have effect ?

A

Conventional DMARDs have a slow onset of action and can take 2-3 months to take effect.

28
Q

Which antifungal tablets are indicated for tinea corporis ?

A

terbinafine tablets

29
Q

What are the risk factors for CHD ?

A
  • diabetes
  • dyslipidemia
  • hypertension
  • lack of exercise
30
Q

Amphetamines belong to which schedule of controlled drugs?

A

schedule 2

31
Q

is lorazepam allowed on repeats ?

A

yes because it is schedule 4

32
Q

Which foods contain large amount of vitamin K ?

A

liver, broccoli, brussels sprouts, green leafy vegetables

33
Q

You receive a supply order for diamorphine from a registered midwife.
Which one of the following is NOT required to be on the supply order?
-address of the midwife
-name of midwife
-name of patient
-occupation of midwife
-purpose for which the diamoprhine is required

A

The address of the midwife is not required on a supply order.

34
Q

A doctor asks for advice regarding dyspepsia. A patient is complaining of worsening dyspepsia.
Which of the following will NOT exacerbate symptoms of dyspepsia?
-bisphosphonates
-calcium supplements
-doxycycline
-excess alcohol
-prednisolone

A

Calcium supplements will not exacerbate symptoms of dyspepsia. The rest of these will and should be avoided where possible to reduce worsening dyspepsia.

35
Q

Which one of the following is a reason for Mrs K to stop her HRT immediately?

  • alopecia
  • exfoliative dermatitis
  • nausea
  • severe stomach pain
  • severe unexplained sore throat, fever or malaise
A

Hormone replacement therapy should be stopped (pending investigation and treatment), if severe stomach pains occur.

36
Q

Which of the following classifications require no licence to import or export the controlled drug?

  • schedule 2
  • schedule 3
  • schedule 4 part 1
  • schedule 4 part 2
  • schedule 5
A

Schedule 5 Controlled Drugs require no special license for either exportation or importation.

Exam questions (2 decks)

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