on track Flashcards
What is fidaxomicin used for ?
used to treat c.difficile
Describe most likely interaction between tricyclics and opioids?
sedation
Why Beta 2 agonists must be used with caution in patients with diabetes, especially intravenous salbutamol ?
Can cause ketoacidosis
What is interaction between statins and daptomycin ?
increase the risk of rhabdomyolysis
Which drug can cause hallucinations from the list below?
- paracetamol
- dantrolene
- baclofen
- benfroflumethiazide
- metformin
BACLOFEN
Interaction between warfarin and cranberry juice?
cranberry juice is enzyme inhibitor, increase warfarin concentrations
Which drug from the list below can cause dyspepsia?
- atenolol
- bendro
- lisinopril
- nifedipine
- valsartan
-Nifedipine
Calcium antagonists, nitrates, theophyllines, bisphosphonates, corticosteroids and nonsteroidal anti-inflammatory drugs can cause dyspepsia.
According to SPC can lisinopril cause hypokalaemia or hyperkalaemia ?
hyperkalaemia
When would it be the legal obligation to report female genital mutilation ?
“All pharmacy professionals now have a legal duty to report, orally or in writing, to the police if: they observe physical signs that female genital mutilation (FGM) may have taken place in a girl under the age of 18, or a child or young person tells them that they have had FGM.”
Can penicilin V be given for breastfeeding women ?
Penicillin V is considered compatible for breastfeeding but the infant should be monitored for adverse effects.
biphasic insulin aspart 30/70 is long acting or short acting ?
short acting
Insulin can be kept outside the fridge once opened
An elderly woman presents in the pharmacy on a Friday morning complaining of a bothersome headache.
Which one of the following symptom clusters require you to make an urgent referral to the doctor?
-Bilateral generalised headache
-Bilateral headache with symptoms that worsen as the day progresses
-Unilateral frontal headache which worsens on bending down
-Unilateral headache with associated nausea
-Unilateral headache with malaise
Unilateral headache with associated nausea suggests migraine; bilateral generalised headache and bilateral headache with symptoms that worse as the day progresses suggests tension-type headache; unilateral frontal headache which worsens on bending down suggests sinusitis; unilateral headache with malaise could be temporal arteritis.
What side effect can tibolone cause to breasts?
nipple pain
What is osteomyelitis and what is the treatment ?
flucloxacillin
What does MDRD stand for ?
modification of diet in renal disease : MDRD is used to measure. eGFR of a patient
Patients who had a splenectomy should have which vaccine:
- hepatitis B
- hepatitis A
- pneumococcal vaccine
- rabies vaccine
- typhoid vaccine
pneumococcal vaccine because if they had a splenectomy they are at increased risk of pneumococcal infection.
Orlistat may reduce the absorption of which vitamins ?
ADEK: fat soluble
What electrolyte disturbance mirtazapine can cause ?
hyponatraemia
Which ONE of the following is most likely to cause dry mouth ?
- salbutamol
- salmeterol
- ipratropium
- terbutaline
- theophylline
ipratropium is antimuscarinic drug and therefore can cause dry mouth
Mr G is a 78-year-old retired school teacher. He has arthritis and is experiencing severe discomfort in his movements.
Which one of the following allied healthcare professionals is the most suitable to assess and support Mr G with his discomfort and could provide the patient with the support aids to assist him?
-dietitian
-occupational therapist
-orthotist
-support worker
ORTHOTIST: provide support to correct problems or deformities in peoples nerves, muscles or bones. Examples include splints, braces and special footwear
Clenbuterol is part of which schedule ?
schedule 4 part 2
Mrs R is a patient who has AIDS. She has been diagnosed with mild pneumocystis pneumonia. She is unable to tolerate trimethoprim.Which single medication is the most likely treatment option for her pneumonia?
- atovaquone
- co-trimoxazole
- hydrocortisone
- pentamidine isetionate
- prednisolone
Atovaquone is licensed for the treatment of mild to moderate pneumocystis infection in patients who cannot tolerate co-trimoxazole (co-trimoxazole is made up of sulfamethoxazole and trimethoprim - Note that Mrs R can not tolerate trimethoprim). The other options are suitable for severe pneumocystis infection.
Mr K is a 21-year-old student who comes to your pharmacy with a new prescription for himself. You look at the prescription and advise Mr K to report immediately any sore throat, fever, infection, unexplained bleeding and bruising, purpura, mouth ulcers or rashes to their doctor.
Which of the following drugs is this counselling advice most suitable for?
-bezafibrate
-glucosamine
-loperamide
-penicillamine
-sumatriptan
Penicillamine has been associated with blood disorders. Therefore, patients should be counselled to report these signs immediately to their doctor, if and when they develop.
Mrs H is a 82-year-old retired pilot. She has chronic kidney disease (CKD) with the following reported values: eGFR: 25 ml/min/1.73 m2, ACR: 17 mg/mmol.
Which one of the following drugs is LEAST suitable for use in Mrs H?
-allopurinol
-atenolol
-metformin
-paracetamol
-simvastatin
metformin: avoid if eGFR is less than 30 ml/min
