ON 2 Flashcards
T/F: Optic Nerve Hypoplasia is a unilateral condition
Eh, actually it can be both lol
Unilateral: likely strab & APD
T/F: ON Hypoplasia is congenital
TRUE (not progressive)
Potential causes for OH Hypoplasia
- Toxicity
- Infection
- Ischemia
- Idiopathic
Expected VA for ON Hypoplasia
20/20 to NLP (just varies 🤷🏻♀️)
Describe the nerve fiber layer in ONE Hypoplasia
LESS fibers (thinned retina)
Double pigment ring sign
Yellow-white peripapillary halo, absence of RPE (represents size of normal ONH)
How do retinal vessels appear in ON Hypoplasia?
Appears larger and enters disc centrally, may be tortuous
Septo Optic Dysplasia
Rare congenital defect during embryological development
Triad for SOD
- ON Hypoplasia
- Absence (partial or complete) of septum pellucidum/corpus colluscum
- Hypopituitarism
T/F: Optic Atrophy is hereditary
TRUE
Which OA exhibits the best VA?
Juvenile AD OA
Expected vision in Congenital AR OA?
Worse than 20/200
TX for Congenital AR OA?
Genetic counseling and low vision/rehab
Juvenile AD OA exhibits pallor in which quadrant?
Temporal
What VF defect in Juvenile AD OA?
Cecocentral scotoma
Describe the vision loss in Juvenile AD OA
Gradual 4-12 yo
Juvenile AD OA involves a defect on Chromosome ___
3
TX for Juvenile AD OA
Low vision devices, cochlear implants, genetic counseling, and routine f/u
note: neuro-imaging require to rule out other causes
Genetic transmission of Leber’s
X-linked recessive
(Mitochondrial mutation in DNA)
What defect precedes atrophy in Juvenile AD OA?
Blue yellow color defect
Systemic deficits also exhibited in Juvenile AD OA
Hearing loss and ataxia
Main ocular symptom of Leber’s
Severe vision loss (worse than 20/200)
VF defect in Leber’s
Central and cecocentral scotoma
Triad of Leber’s
- Circumpapillary telangiectasia of BV
- Pseudoedema
- Absense of leakage on FA
ON Glioma arise from _____ of the ON and visual pathway
Astrocytes
Typical ON Glioma pt
Female < 20 yo
