OME FC's

Question 1

Infant male w/sinopulmonary infections:
? Dx
? Lab findings

Answer 1

X-linked Agammaglobulinemia (Bruton’s)

Lab: Zero Ig’s + BTK gene

Question 2

Teen with sinopulm (sinusitis, otitis, pna) infections and zero Ig’s?

Answer 2

CVID (common variable immunideficiency)

Question 3

Anaphylaxis post transfusion

Answer 3

IgA deficiency

Question 4

Low IgA, IgG

High IgM

Answer 4

Hyper IgM syndrome

Question 5

? Ppx, tx and f/u for DiGeorges?

Answer 5

Ppx: TMP-SMX
Tx: IVIG –> tymic transplant
F/u: hypocalcemia (tetany and seizures)

Question 6

Boy with eczema
Low plt
Normal infections

Answer 6

Wiskott-Aldrich

Question 7

Ataxia
Telangiectasias

Pt is at risk for what?

Answer 7

Ataxia-telangiectasia

Risk of leuk/lymphoma

Question 8

Infant w/”AIDS”

Tx

Answer 8

SCID

Tx: bone marrow transplant

Question 9

Staph abscesses

?Dx and Test

Answer 9

CGD

Nitro blue is NEGATIVE

Question 10

Fever
Elevated WBC
NO PUS
Delayed cord separation

Answer 10

LAD

Tx: BMT

Question 11

Giant granules in neutrophiles

Answer 11

Chediak-Higashi

Question 12

Non drug related angioedema

Answer 12

C1 esterase

Question 13

Neisseria infections

Answer 13

C5-C9 deficiency

Question 14

Mneumonic for causes of secondary HTN?

Answer 14

Tripple HART(P) CO.

Hyper aldo
Hyper Ca
Hyper thyroid
Aorta - coarctation
Renal
(T) Pheo
Cuhings
OSA

Question 15

Who must be on a statin?

Which statins should they be on?

Answer 15

1. Vascular dz
2. LDL > 190
3. DM (and age 40-75)
4. • Calculated risk

EVERYONE should be on HIGH intensity (unless CI)
Atorvastatin 40, 80
Rosuvastain 20, 40

CI - intolerance, age > 75, Liver or Renal Dz

Question 16

Symptoms of Serotonin Syndrome:

Answer 16

Agitation, AMS
Ataxia
Diaphoresis
Diarrhea
Hyperreflexia
Myoclonus
Tremor
Shivering
Hyperthermia

(*did not recently start a neuroleptic med)

Question 17

Lights criteria that indicates an exudate on plural effusion:

Answer 17

LDHf > 2/3 ULN (OR)

LDHf:LDHs >0.6 (OR)

TPf:TPs >0.5

Question 18

When do you not tap a plural effusion?

Answer 18

Too small < 1cm
its CHF
Its Loculated

Question 19

Low blood cell counts
Joint pain
Splenomegaly

Answer 19

Felty’s Syndrome (autoimmune do)

• RA
• neutropenia
• splenomegaly