Olfactory Nerve Flashcards

1
Q

What kind of nerve is the Olfactory Nerve?

A

SSA - Special Sensory Afferent

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2
Q

Where does Olfaction begin?

A

Olfactory Epithelium

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3
Q

Where is the Olfactory Epithelium located?

A

Roof of the nasal cavity, and extends into the superior nasal conchae and nasal septum

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4
Q

What allows scent molecules to by captured and dissolved?

A

Nasal mucosa keeping the area moist

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5
Q

What do olfactory epithelia have in the mucosal layer?

A

Small ciliary processes

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6
Q

What do ciliary r/c transmit?

A

Sensory input into the bipolar olfactory epithelium

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7
Q

Where does sensory information transmit after the bipolar olfactory epithelium?

A

Though the cribriform plate into the olfactory bulb

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8
Q

When does olfactory transduction begin?

A

Olfactant binding to r/c on ciliary processes

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9
Q

What happens when olfactant binds to ciliary processes?

A

G-protein activation results in inc in intracellular cAMP, creating graded r/c potential

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10
Q

What allows for discrimination of up to 10,000 different smells?

A

Variations in r/c protein coupled with CNS integration.

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11
Q

What is the olfactory bulb?

A

A 5 layered area at the rostral enlargement of the olfactory tract

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12
Q

How are the olfactory tracts related to embryonic development?

A

The olfactory tracts are telencephalic outpouchings

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13
Q

What does the olfactory area house?

A

second order neurons

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14
Q

Where do nerve fibers project?

A

From the mucosal layer to the 2nd layer of the bulb

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15
Q

What is the 2nd layer of the olfactory bulb called?

A

The Glomerular layer

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16
Q

What are Glomerular neurons?

A

Interneurons between the ascending neuroepithelial nerve fibers from layer 1 and the descending fibers from the mitral cells in layer 4

17
Q

What do Glomerular neurons also integrate with?

A

Tufted cells from layer 3.

18
Q

What is the 3rd layer of the olfactory bulb called?

A

External Plexiform Layer

19
Q

What interneuron cell group is in the 5th layer of the olfactory bulb?

A

Granular cells

20
Q

Describe the 5 layers of the Olfactory Bulb

A
  1. Nerve Fiber Layer
  2. Glomerular Layer
  3. Tufted Cell Layer
  4. Mitral Cell Layer
  5. Granule Cell Layer
21
Q

What composes the olfactory tract?

A

The projections of the mitral and tufted cell layers

22
Q

What does the olfactory tract divide into?

A

Medial and Lateral Olfactory Stria

23
Q

Where is the division of the olfactory tract?

A

In the olfactory trigone, anterior to the perforated substance

24
Q

Which division carries the majority of olfactory information.

A

Lateral Stria

25
Q

Where does the Lateral Stria take information to?

A

Lateral Primary Olfactory Area

26
Q

What does the olfactory area consist of?

A

Uncut
Entorhinal area
Insula
Amygdaloid Body

27
Q

Where does the medial olfactory stria project to?

A

Medial olfactory area

28
Q

Where is the medial olfactory area located?

A

Medial surface of the frontal lobe

29
Q

What functional system is the medial surface of the frontal closely associated with?

A

Limbic System

30
Q

What is the Primary Olfactory Cx also known as?

A

Piriform and Periamygdaloid Cx