Older persons medicine Flashcards

1
Q

Osteoporosis

A

Presence of bone mineral density of less than 2.5 standard deviations below the young adult mean density

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2
Q

Osteoporosis risk factors

A

Age

Female gender

Corticosteroid use

Smoking

Alcohol

Low BMI

Family history

Medications - SSRIs, antiepileptics, PPIs, glitazones, long term heparin therapy, aromatase inhibitors

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3
Q

FRAX score

A

Estimates 10-year risk of fragility fracture

Valid for patients aged 40-90

Assesses the following factors - age, sex, weight, height, previous fracture, parental fracture, current smoking, glucocorticoids, RA, secondary osteoporosis, alcohol intake

DEXA scan if FRAX shows intermediate result

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4
Q

QFracture

A

Estimates the 10 year risk of fragility fracture

Can be used for patients aged 30-99 years

Larger group of risk factors

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5
Q

Results of FRAX

A

If FRAX was done without BMD, results are as follows:

  • low risk: reassure & lifestyle advice
  • intermediate risk: offer BMD test
  • high risk: offer bone protection treatment

If FRAX done with BMD, results → reassure, consider treatment or strongly recommended treatment

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6
Q

Assessing patients following a fragility fracture

A

Patients ≥ 75 years of age:

  • should be started on oral bisphosphonate without need for DEXA scan

Patients < 75 years of age:

  • DEXA scan arranged → enter into FRAX score which will determine risk
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7
Q

DEXA scan results

A

> -1 = normal

-1 to -2.5 = osteopenia

< -2.5 = osteoporosis

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8
Q

Osteoporosis mx

A

Vitamin D and calcium supplementation

Alendronate is first line

25% cannot tolerate alendronate (upper GI SEs) → offer risedronate/etidronate

If cannot tolerate bisphosphonates → strontium ranelate & raloxifene

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9
Q

Pressure ulcers

A

Develop in patients who are unable to move parts of their body due to illness, paralysis or advancing age

Typically happen over bony prominences e.g. sacrum or heel

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10
Q

Pressure ulcers risk factors

A

Malnourishment

Incontinence - urinary & faecal

Lack of mobility

Pain

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11
Q

Waterlow score

A

Widely used to screen for patients who are at risk of developing pressure areas

Includes a number of factors - BMI, nutritional status, skin type, mobility & continence

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12
Q

Grading of pressure ulcers

A

European pressure ulcer advisory panel classification system

Grade 1 - non-blanchable erythema of intact skin

Grade 2 - partial thickness skin loss involving epidermis/dermis/both. Ulcer is superficial & presents clinically as an abrasion or blister

Grade 3 - full thickness skin loss involving damage to/necrosis of subcutaneous tissue that may extended down to (not through) underlying fascia

Grade 4 - extensive destruction, tissue necrosis, damage to muscle, bone or supporting structures with/without full thickness skin loss

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13
Q

Pressure ulcers mx

A

Moist wound environment encourages ulcer healing → hydrocolloid dressings & hydrogels; use of soap discouraged

Wound swabs not done routinely

Referral to tissue viability nurse

Surgical debridement for selected wounds

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14
Q

Gait and falling

A

Normal gait involves:

  • neurological system: basal ganglia & cortical basal ganglia loop
  • MSK system
  • effective processing of the senses eg. sight, sound, sensation

Older → more likely to experience medical problems affecting these systems

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15
Q

Falls risk factors

A

Fallen previously

Lower limb muscle weakness

Vision problems

Balance/gait disturbances

Polypharmacy

Incontinence

Depression

Postural hypotension

Arthritis in lower limbs

Psychoactive drugs

Cognitive impairment

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16
Q

Falls hx

A

Where, when?

Did anyone else see the fall?

What happened? Any associated features?

Why?

Fallen before?

Systems review?

PMHx

SHx

17
Q

Medications that cause postural hypotension

A

Nitrates

Diuretics

Anticholinergic medications

Antidepressants

Beta-blockers

L-DOPA

ACE inhibitors

18
Q

Medications associated with falls due to other mechanisms

A

Benzodiazepines

Antipsychotics

Opiates

Anticonvulsants

Codeine

Digoxin

Other sedative agents

19
Q

Falls ix

A

Bedside - obs, BP, BM, urine dip, ECG

Bloods - FBC, U&Es, LFTs, bone profile

Imaging - XR chest/injured limbs, CT head & cardiac echo

20
Q

Falls mx

A

Offer MDT assessment by a qualified clinician to all patients > 65:

  • > 2 falls in last 12 months
  • fall requires medical treatment
  • poor performance/failure to complete ‘turn 180 test’ or ‘timed up and go test’
21
Q

Urinary incontinence risk factors

A

Advancing age

Previous pregnancy & childbirth

High BMI

Hysterectomy

Family history

22
Q

Urinary incontinence classification

A

Overactive bladder/urge incontinence - due to detrusor overactivity

  • urge to urinate is quickly followed by uncontrollable leakage ranging from a few drops to complete bladder emptying

Stress incontinence - leaking small amounts when coughing/laughing

Mixed incontinence - both urge & stress

Overflow incontinence - due to bladder outlet obstruction

  • prostate enlargement

Functional incontinence - comorbid physical conditions impair the patient’s ability to get to a bathroom in time

  • dementia, sedating meds, injury/illness resulting in decreased ambulation
23
Q

Urinary incontinence ix

A

Bladder diaries

Vaginal examination to exclude pelvic organ prolapse

Urine dipstick & culture

Urodynamic studies

24
Q

Urge incontinence management

A

Bladder retraining - lasts for a min 6 weeks

Bladder stabilising drugs - antimuscarinics

  • oxybutynin (immediate release), tolterodine (IR) or darifenacin (once daily preparation)
  • IR oxybutynin - avoid in ‘frail older women’

Mirabegron (B3 agonist) if concern about anticholinergic SEs in frail elderly patients

25
Q

Stress incontinence management

A

Pelvic floor muscle training - min. 3 months

Surgical procedures

Duloxetine - women who decline surgical procedures